Alessandro Paiardini

Pubblicazioni

Titolo Pubblicato in Anno
Identification of the pyridoxal 5′‐phosphate allosteric site in human pyridox(am)ine 5′‐phosphate oxidase PROTEIN SCIENCE 2024
A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression CANCER GENE THERAPY 2023
AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation LIFE SCIENCE ALLIANCE 2023
Revisiting degron motifs in human AURKA required for its targeting by APC/CFZR1 LIFE SCIENCE ALLIANCE 2023
Centaurea triumfetii essential oil chemical composition, comparative analysis, and antimicrobial activity of selected compounds SCIENTIFIC REPORTS 2023
Fatty Acids Abolish Shigella Virulence by Inhibiting Its Master Regulator, VirF MICROBIOLOGY SPECTRUM 2023
Bivalent binding of staphylococcal superantigens to the TCR and CD28 triggers inflammatory signals independently of antigen presenting cells FRONTIERS IN IMMUNOLOGY 2023
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8 JOURNAL OF MEDICINAL CHEMISTRY 2023
When Just One Phosphate Is One Too Many: The Multifaceted Interplay between Myc and Kinases INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
Diffusible signal factors (DSFs) bind and repress VirF, the leading virulence activator of Shigella flexneri SCIENTIFIC REPORTS 2023
Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa. MICROBIOLOGICAL RESEARCH 2023
Exploring Innovative Approaches to Isolate a One-Component c-di-GMP Transducer: A Pilot Study ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 2023
A deep neural network for G-quadruplexes binding proteins classification Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2023
PyPCN: protein contact networks in PyMOL BIOINFORMATICS 2023
The phosphodiesterase RmcA contributes to the adaptation of Pseudomonas putida to l-arginine FEMS MICROBIOLOGY LETTERS 2023
A conserved scaffold with heterogeneous metal ion binding site: the multifaceted example of HD-GYP proteins COORDINATION CHEMISTRY REVIEWS 2022
Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex THE FEBS JOURNAL 2022
Prediction and modeling of protein–protein interactions using “Spotted” peptides with a template-based approach BIOMOLECULES 2022
Nutrient sensing and biofilm modulation: the example of L-arginine in Pseudomonas INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
A Novel Hypothesis on Choroideremia-Manifesting Female Carriers: Could CHM In-Frame Variants Exert a Dominant Negative Effect? A Case Report GENES 2022

ERC

  • LS1
  • LS1_8
  • LS1_12
  • LS1_14
  • LS2_11

KET

  • Big data & computing
  • Life-science technologies & biotechnologies

Interessi di ricerca

Bioinformatics, Computational Biology, Medicinal Chemistry, Drug Design, Protein Structure Prediction, Deep Learning, GUI programming, Python, Cancer, Kinases

Gruppi di ricerca

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