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gabriele.ruffolo@uniroma1.it
Gabriele Ruffolo
Ricercatore
Struttura:
DIPARTIMENTO DI FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER"
E-mail:
gabriele.ruffolo@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Impaired GABAergic regulation and developmental immaturity in interneurons derived from the medial ganglionic eminence in the tuberous sclerosis complex
ACTA NEUROPATHOLOGICA
2024
Membranes and Synaptosomes Used to Investigate Synaptic GABAergic Currents in Epileptic Patients
MEMBRANES
2024
Selective modulation of epileptic tissue by an adenosine A3 receptor-activating drug
BRITISH JOURNAL OF PHARMACOLOGY
2024
WONOEP appraisal: The role of glial cells in focal malformations associated with early onset epilepsies
EPILEPSIA
2024
Intranasal administration of KYCCSRK peptide rescues brain insulin signaling activation and reduces Alzheimer’s disease-like neuropathology in a mouse model for Down syndrome
ANTIOXIDANTS
2023
Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models
INFLAMMATION AND REGENERATION
2023
Traditional and Innovative Anti-seizure Medications Targeting Key Physiopathological Mechanisms: Focus on Neurodevelopment and Neurodegeneration
CURRENT NEUROPHARMACOLOGY
2023
Plasma biomarker profile and clinical correlations in adult patients with tuberous sclerosis complex
NEUROLOGY
2023
Olfactory impairment in autoimmune encephalitis: another piece of the puzzle
JOURNAL OF NEUROLOGY
2022
A systems-level analysis highlights microglial activation as a modifying factor in common epilepsies
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
2022
Lipid mediator n-3 docosapentaenoic acid-derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G-protein-coupled receptor
THE FASEB JOURNAL
2022
Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity
BIOMEDICINES
2022
Classical and Unexpected Effects of Ultra-Micronized {PEA} in Neuromuscular Function
BIOMOLECULES
2022
Unexpected Effect of IL-1beta on the Function of GABAA Receptors in Pediatric Focal Cortical Dysplasia
BRAIN SCIENCES
2022
Effects of 3,4-diaminopyridine on myasthenia gravis: Preliminary results of an open-label study
FRONTIERS IN PHARMACOLOGY
2022
GABAA receptor function is enhanced by Interleukin-10 in human epileptogenic gangliogliomas and its effect is counteracted by Interleukin-1β
SCIENTIFIC REPORTS
2022
Late-onset seizures and epilepsy: Electroclinical features suggestive of autoimmune etiology.
FRONTIERS IN NEUROLOGY
2022
GABAergic neurotransmission in human tissues is modulated by cannabidiol
LIFE
2022
Dissecting the molecular determinants of GABAA receptors current rundown, a hallmark of refractory human epilepsy
BRAIN SCIENCES
2021
Functional Gastrointestinal Disorders in Patients With Epilepsy: Reciprocal Influence and Impact on Seizure Occurrence
FRONTIERS IN NEUROLOGY
2021
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Progetti di Ricerca
Citochine come modulatori della neurotrasmissione: studio dell' effetto dell' interleuchina-10
Alterazioni funzionali della trasmissione sinaptica nelle mTORopatie rare.
Varianti patologiche della trasmissione GABAergica e glutammatergica nelle patologie dello sviluppo cerebrale: elementi comuni come prospettive terapeutiche future.
Studio delle alterazioni della neurotrasmissione come meccanismo patogenetico e bersaglio terapeutico nella sindrome di Dravet.
Gruppi di ricerca
Gruppo di ricerca sulla sclerosi laterale amiotrofica
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