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Dante.Rotili@uniroma1.it
Dante Rotili
Professore Associato
Struttura:
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
E-mail:
Dante.Rotili@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53
JOURNAL OF MEDICINAL CHEMISTRY
2021
JQ1, inibitore delle proteine BET, riduce i fattori di virulenza e la patogenicità di Aspergillus fumigatus.
13° Congresso Nazionale della Società Italiana di Microbiologia Farmaceutica Obiettivi e Sfide della Microbiologia Moderna per la Difesa della Salute
2021
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions
CHEMICAL COMMUNICATIONS
2021
Emerging Therapeutic Potential of SIRT6 Modulators
JOURNAL OF MEDICINAL CHEMISTRY
2021
Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression
GASTROENTEROLOGY
2021
Tranylcypromine-based LSD1 inhibitors: structure-activity relationships, antiproliferative effects in leukemia, and gene target modulation
CHEMMEDCHEM
2020
Sirtuin modulators: where are we now? A review of patents from 2015 to 2019
EXPERT OPINION ON THERAPEUTIC PATENTS
2020
Radioguided surgery with β− radiation in pancreatic Neuroendocrine tumors: a feasibility study
SCIENTIFIC REPORTS
2020
From parp1 to tnks2 Inhibition: a structure-based approach
ACS MEDICINAL CHEMISTRY LETTERS
2020
Identification of Inhibitors to trypanosoma cruzi sirtuins based on compounds developed to human enzymes
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
The pan-sirtuin inhibitor MC2494 regulates mitochondrial function in a leukemia cell line
FRONTIERS IN ONCOLOGY
2020
Sirt4: a multifaceted enzyme at the crossroads of mitochondrial metabolism and cancer
FRONTIERS IN ONCOLOGY
2020
Targeting histone acetylation/deacetylation in parasites: an update (2017–2020)
CURRENT OPINION IN CHEMICAL BIOLOGY
2020
Characterization of water-soluble esters of nitrobenzoxadiazole-based GSTP1-1 inhibitors for cancer treatment
BIOCHEMICAL PHARMACOLOGY
2020
Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni
PLOS NEGLECTED TROPICAL DISEASES
2020
CDK9 as a valuable target in cancer: from natural compounds inhibitors to current treatment in pediatric soft tissue sarcomas
FRONTIERS IN PHARMACOLOGY
2020
Recent advances in epigenetic proteolysis targeting chimeras (Epi-PROTACs)
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2020
HAT inhibitors in cancer therapy
Histone Modifications in Therapy
2020
Lysine Acetyltransferase Inhibitors From Natural Sources
FRONTIERS IN PHARMACOLOGY
2020
Identification of novel quinazoline derivatives as potent antiplasmodial agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2019
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Progetti di Ricerca
Modulators of epigenetic targets for the treatment of parasitic diseases.
Development of novel LSD1 inhibitors as potential new generation anticancer agents.
Development of glucose-based pure beta minus radiotracers potentially suitable for tumor radioguided surgery.
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