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dante.rotili@uniroma1.it
Dante Rotili
Professore Associato
Struttura:
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
E-mail:
dante.rotili@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa.
MICROBIOLOGICAL RESEARCH
2023
The role of structural biology in the design of sirtuin activators
CURRENT OPINION IN STRUCTURAL BIOLOGY
2023
State of the art of carbonic anhydrase activators
FUTURE MEDICINAL CHEMISTRY
2023
Hydroxamate-based compounds are potent inhibitors of Toxoplasma gondii HDAC biological activity
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2023
SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells
INFLAMMATION
2023
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase
ACS CHEMICAL BIOLOGY
2023
BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress
ANTIOXIDANTS
2023
HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
2023
Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3
CANCER COMMUNICATIONS
2023
BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress
ANTIOXIDANTS
2023
Hydrophilic gold nanoparticles as Anti-PD-L1 antibody carriers. Synthesis and interface properties
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
2022
Multimodal evaluation of 19F-BPA internalization in pancreatic cancer cells for boron capture and proton therapy potential applications
PHYSICA MEDICA
2022
Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription
NUCLEIC ACIDS RESEARCH
2022
The Nitrobenzoxadiazole Derivative NBDHEX Behaves as Plasmodium falciparum Gametocyte Selective Inhibitor with Malaria Parasite Transmission Blocking Activity
PHARMACEUTICALS
2022
A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
2022
Neuroprotective effects of PARP inhibitors in Drosophila models of Alzheimer’s disease
CELLS
2022
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2022
Sirtuin modulators: past, present, and future perspectives
FUTURE MEDICINAL CHEMISTRY
2022
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni
ACS INFECTIOUS DISEASES
2022
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Progetti di Ricerca
Modulators of epigenetic targets for the treatment of parasitic diseases.
Development of novel LSD1 inhibitors as potential new generation anticancer agents.
Development of glucose-based pure beta minus radiotracers potentially suitable for tumor radioguided surgery.
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