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dante.rotili@uniroma1.it
Dante Rotili
Professore Associato
Struttura:
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
E-mail:
dante.rotili@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
2023
Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3
CANCER COMMUNICATIONS
2023
BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress
ANTIOXIDANTS
2023
Hydrophilic gold nanoparticles as Anti-PD-L1 antibody carriers. Synthesis and interface properties
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
2022
Multimodal evaluation of 19F-BPA internalization in pancreatic cancer cells for boron capture and proton therapy potential applications
PHYSICA MEDICA
2022
Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription
NUCLEIC ACIDS RESEARCH
2022
The Nitrobenzoxadiazole Derivative NBDHEX Behaves as Plasmodium falciparum Gametocyte Selective Inhibitor with Malaria Parasite Transmission Blocking Activity
PHARMACEUTICALS
2022
A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
2022
Neuroprotective effects of PARP inhibitors in Drosophila models of Alzheimer’s disease
CELLS
2022
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2022
Sirtuin modulators: past, present, and future perspectives
FUTURE MEDICINAL CHEMISTRY
2022
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni
ACS INFECTIOUS DISEASES
2022
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5
JOURNAL OF MEDICINAL CHEMISTRY
2022
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells
CANCER GENE THERAPY
2022
Chemically Diverse S. mansoni HDAC8 Inhibitors Reduced Viability in Worm Larval and Adult Stages
CHEMMEDCHEM
2022
Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics
MOLECULAR METABOLISM
2022
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells
CANCER GENE THERAPY
2022
Modulation of virulence-associated traits in Aspergillus fumigatus by BET Inhibitor JQ1
MICROORGANISMS
2022
Regulatory interplay between mir-181a-5p and estrogen receptor signaling cascade in breast cancer
CANCERS
2021
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Progetti di Ricerca
Modulators of epigenetic targets for the treatment of parasitic diseases.
Development of novel LSD1 inhibitors as potential new generation anticancer agents.
Development of glucose-based pure beta minus radiotracers potentially suitable for tumor radioguided surgery.
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