Pubblicazioni

Interfering with the Ubiquitin-Mediated Regulation of Akt as a Strategy for Cancer Treatment

2023 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Paccosi, E.; Balzerano, A.; Proietti-De-Santis, L.

The Exosome-Mediated PI3K/Akt/mTOR Signaling Pathway in Neurological Diseases

2023 - PHARMACEUTICS

Iranpanah, Amin; Kooshki, Leila; Zachariah Moradi, Seyed; Saso, Luciano; Fakhri, Sajad; Khan, Haroon

Hydroxytyrosol Counteracts Triple Negative Breast Cancer Cell Dissemination via Its Copper Complexing Properties

2023 - BIOLOGY

Perta, Nunzio; Torrieri Di Tullio, Laura; Cugini, Elisa; Fattibene, Paola; Rapanotti, Maria Cristina; Borromeo, Ilaria; Forni, Cinzia; Malaspina, Patrizia; Cacciamani, Tiziana; Di Marino, Daniele; Rossi, Luisa; De Luca, Anastasia

Hyperactive Akt1 Signaling Increases Tumor Progression and DNA Repair in Embryonal Rhabdomyosarcoma RD Line and Confers Susceptibility to Glycolysis and Mevalonate Pathway Inhibitors

2022 - CELLS

Codenotti, Silvia; Zizioli, Daniela; Mignani, Luca; Rezzola, Sara; Tabellini, Giovanna; Parolini, Silvia; Giacomini, Arianna; Asperti, Michela; Poli, Maura; Mandracchia, Delia; Vezzoli, Marika; Bernardi, Simona; Russo, Domenico; Mitola, Stefania; Monti, Eugenio; Triggiani, Luca; Tomasini, Davide; Gastaldello, Stefano; Cassandri, Matteo; Rota, Rossella; Marampon, Francesco; Fanzani, Alessandro

Survival pathways are differently affected by microgravity in normal and cancerous breast cells

2021 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Monti, N.; Masiello, M. G.; Proietti, S.; Catizone, A.; Ricci, G.; Harrath, A. H.; Alwasel, S. H.; Cucina, A.; Bizzarri, M.

The PI3K pathway induced by Î±MSH exerts a negative feedback on melanogenesis and contributes to the release of pigment

2021 - PIGMENT CELL & MELANOMA RESEARCH

Mosca, S.; Cardinali, G.; Flori, E.; Briganti, S.; Bottillo, I.; Mileo, A. M.; Maresca, V.

CircVAMP3: A circRNA with a role in alveolar rhabdomyosarcoma cell cycle progression

2021 - GENES

Rossi, Francesca; Alvaro, CentrÃ³n-Broco; Dattilo, Dario; Di Timoteo, Gaia; Guarnacci, Marco; Colantoni, Alessio; Beltran Nebot, Manuel; Bozzoni, Irene

Î²-arrestin 2 is required for dopamine receptor type 2 inhibitory effects on AKT phosphorylation and cell proliferation in pituitary tumors.

2020 - NEUROENDOCRINOLOGY

Mangili, Federica; Giardino, Elena; Treppiedi, Donatella; Barbieri, Anna Maria; Catalano, Rosa; Locatelli, Marco; Lania, Andrea Gerardo; Spada, Anna; Arosio, Maura; Mantovani, Giovanna; Peverelli, Erika

Autocrine bradykinin release promotes ischemic preconditioning-induced cytoprotection in bovine aortic endothelial cells

2020 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bellis, A.; Sorriento, D.; Fiordelisi, A.; Izzo, R.; Sadoshima, J.; Mauro, C.; Cerasuolo, F.; Mancusi, C.; Barbato, E.; Pilato, E.; Trimarco, B.; Morisco, C.

Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease

2019 - NEUROBIOLOGY OF DISEASE

Sharma, Nidhi; Tramutola, Antonella; Lanzillotta, Chiara; Arena, Andrea; Blarzino, Carla; Cassano, Tommaso; Butterfield, D. Allan; Di Domenico, Fabio; Perluigi, Marzia; Barone, Eugenio

Novel kinase inhibitors afuresertib and pim447 are active in a predictive myeloma in vivo model, and a crispr genome-wide screening approach identifies biomarkers determining susceptibility

2018 - HEMASPHERE

Keane, N.; Sharik, M.; Natoni, A.; Chesi, M.; Bergsagel, L.; Michael, O.

Thyroid hormone regulates fibronectin expression through the activation of the hypoxia inducible factor 1

2017 - BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Taglieri, Ludovica; Nardo, Tiziana; Vicinanza, Roberto; Ross, Jaime M.; Scarpa, Susanna; Coppotelli, Giuseppe

Polyfunctional Melan-A-specific tumor-reactive CD8+ T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS

2016 - ONCOIMMUNOLOGY

Ornella, Franzesea; Belinda, Palermobc; Cosmo Di, Donnac; Isabella, Sperdutid; Virginia, Ferraresie; Stabile, MARIA HELENA; Gismondi, Angela; Santoni, Angela

Trop-2 induces tumor growth through AKT and determines sensitivity to AKT inhibitors

2016 - CLINICAL CANCER RESEARCH

Guerra, Emanuela; Trerotola, Marco; Tripaldi, Romina; Aloisi, Anna Laura; Simeone, Pasquale; Sacchetti, Andrea; Relli, Valeria; D'AMORE, ANTONELLA; Sorda, Rossana La; Lattanzio, Rossano; Piantelli, Mauro; Alberti, Saverio

Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells.

2015 - ONCOSCIENCE

Amantini, C; Morelli, MARIA BEATRICE; Santoni, M; Soriani, Alessandra; Cardinali, Claudio; Farfariello, Valerio; Eleuteri, Am; Bonfili, L; Mozzicafreddo, M; Nabissi, M; Cascinu, S; Santoni, G.

Structure and Validity of Affect Knowledge Test (AKT) in a Sample of Italian Preschoolers

2015 - THE JOURNAL OF GENETIC PSYCHOLOGY

Sette, Stefania; Bassett, Hideko H.; Baumgartner, Emma; Denham, Susanne A.

Concurrent Inhibition of Pim and Akt Pathways with Pim447 and Afuresertib Activates FOXO3a and Depletes c-Myc to Induce Synergistic Cell Death in Multiple Myeloma

2015 - BLOOD

Keane, N; Reidy, M; Natoni, A; O'Dwyer, M