Pubblicazioni

Safety of the oral factor XIa inhibitor asundexian compared with apixaban in patients with atrial fibrillation (PACIFIC-AF). a multicentre, randomised, double-blind, double-dummy, dose-finding phase 2 study

2022 - THE LANCET

Piccini, J. P.; Caso, V.; Connolly, S. J.; Fox, K. A. A.; Oldgren, J.; Jones, W. S.; Gorog, D. A.; Durdil, V.; Viethen, T.; Neumann, C.; Mundl, H.; Patel, M. R.; Auer, J.; Hubauer, M.; Pandzic, S.; Preishuber, E.; Primus-Grabscheit, C.; Reitgruber, D.; Schmalzer, F.; Adlbrecht, C.; Schober, A.; Hajos, J.; Keil, C.; Schratter, A.; Frick, M.; Benda, M. A.; Machler, M.; Mutschlechner, B.; Saely, C.; Sprenger, L.; Lichtenauer, M.; Eber, M.; Hoppe, U.; Kolbitsch, T.; Jirak, P. M.; Mirna, M.; Schonbauer, R.; Bergler-Klein, J.; Hengstenberg, C.; Stojkovic, S.; Scherr, D.; Manninger-Wunscher, M.; Rohrer, U.; Stuhlinger, M.; Schgoer, W.; Schwarzl, J.; Purerfellner, H.; Derndorfer, M.; Ebner, C.; Eder, V.; Kollias, G.; Sturmberger, T.; Sieghartsleitner, S.; Vijgen, J.; Koopman, P.; Dujardin, K.; Anne, W.; De Ceuninck, M.; Tavernier, R.; Duytschaever, M.; Knecht, S.; Missault, L.; Vandekerckhove, Y.; Rossenbacker, T.; Ector, B.; Charlier, F.; Debruyne, P.; Dewilde, W.; Janssens, L.; Roosen, J.; Vankelecom, B.; Heidbuchel, H.; Delesie, M.; Vervoort, G.; Rombouts, H.; Vanassche, T.; Engelen, M.; Verhamme, P.; Willems, R.; Constance, C.; Pranno, N.; Cox, J.; Bata, I.; Macle, L.; Aguilar, M.; Tourigny, J. C.; Dubuc, M.; Dyrda, K.; Guerra, P.; Khairy, P.; Mondesert, B.; Rivard, L.; Roy, D.; Tadros, R.; Talajic, M.; Thibault, B.; Nault, I.; Blier, L.; Champagne, J.; Molin, F.; O'Hara, G.; Philippon, F.; Plourde, B.; Sarrazin, J. -F.; Steinberg, C.; Coufal, Z.; Balazsik, D.; Mikulica, M.; Zapeca, J.; Cermak, O.; Drasnar, T.; Falc, M.; Hornof, J.; Racz, B.; Weissova, D.; Linkova, H.; Paskova, E.; Petr, R.; Sirakova, A.; Kettner, J.; Benak, A.; Holek, M.; Podpera, I.; Podperova, M.; Vancura, V.; Jandik, T.; Smid, J.; Dedek, V.; Banik, J.; Durdil, V.; Hnat, T.; Lellouche, N.; Rouffiac, S.; Taldir, G.; Bridonneau, V.; Couffon, P.; Daudin, M.; Hamon, C.; Lacaze, J.; Quentin, A.; Thebault, C.; Boiffard, E.; Billon, O.; Miette, F.; Pouliquen, H.; Turlotte, G.; Gorka, H.; Albert, F.; Bayle, S.; Bensaid, R.; Dasoveanu, M.; Demichili, T.; Dutoiu, T.; Khalil, C.; Loghin, C.; Range, G.; Roussel, L.; Socie, P.; Thuaire, C.; Extramiana, F.; Algalarrondo, V.; Boughanmi, H.; El Mansour, N.; Mohammad, U.; Sellier, R.; Elbaz, M.; Laperche, C.; Maury, P.; Kiss, R.; Borsanyi, T.; Gingl, Z.; Polgar, B.; Benczur, B.; Bodor, A.; Hepp, T.; Malati, E.; Nagy, L.; Erdei, N.; Kapus, J.; Kapus, K.; Toth, B.; Matoltsy, A.; Kiss, T.; Merkely, B.; Herczeg, S.; Kiss, O.; Sallo, Z.; Toth, K.; Habon, T.; Rabai, M.; Totsimon, K.; Zilahi, Z.; Bencze, G.; Santa, J.; Aradi, D.; Kelemen, B.; Bolognese, L.; Nesti, M.; Notarstefano, P. G.; D'Orazio, S.; Cosmi, F.; Becattini, C.; Agnelli, G.; Broccatelli, B.; Mosconi, M. G.; Paciaroni, M.; Urbini, C.; Parato, V. M.; Notaristefani, C.; Scarano, M.; Ameri, P.; Ghigliotti, G.; Guglielmi, G.; Lotti, R.; Merlo, A. C.; Muiesan, M. L.; Abondio, A.; Berasi, C.; Mattiuzzo, E.; Mutti, C.; Salvetti, M.; Pignatelli, P.; Menichelli, D.; Pastori, D.; Tamiya, E.; Matsumoto, T.; Takabe, T.; Yamamoto, S.; Yamashita, H.; Higashiue, S.; Furuya, O.; Hiramatsu, N.; Kasuga, K.; Kojima, S.; Komooka, M.; Kuroyanagi, S.; Matsuura, M.; Takemoto, T.; Yamamoto, S.; Saito, K.; Abe, T.; Ishida, I.; Iwanami, Y.; Kataoka, S.; Moriyama, T.; Murohashi, A.; Sasaki, A.; Nakamura, Y.; Ueno, T.; Shimane, A.; Hamana, T.; Ichibori, H.; Inoue, T.; Itoh, M.; Iwane, S.; Kawai, H.; Kokawa, T.; Masumoto, A.; Matsuo, K.; Miyata, T.; Nakano, S.; Oishi, S.; Onishi, T.; Sawada, T.; Saito, T.; Shoda, M.; Takahashi, N.; Takaya, T.; Taniguchi, Y.; Tsukamoto, S.; Tsukishiro, Y.; Tsukiyama, Y.; Tsunamoto, H.; Uzu, K.; Yamamoto, H.; Yamamoto, T.; Yokoi, K.; Yoshida, C.; Watanabe, N.; Betsuyaku, T.; Adachi, K.; Awane, K.; Goto, D.; Sakakibara, M.; Watanabe, M.; Ueno, H.; Hiroe, Y.; Matsuo, K.; Ayata, K.; Fukuda, K.; Hata, Y.; Hashimoto, K.; Matsumi, H.; Nikaido, A.; Okamoto, S.; Sime, I.; Stirna, V.; Reinholde, I.; Hansone, S.; Kozlovska, A.; Romanova, J.; Klincare, D.; Pontaga, N.; Dirmans,

"Low dose apixaban as secondary prophylaxis of venous thromboembolism in cancer patients-30 months follow-up": Comment from Serrao et al

2022 - JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Serrao, Alessandra; Assanto, Giovanni Manfredi; Malfona, Francesco; Chavez Orellana, Gabriela; Chistolini, Antonio

Chimeric stimuli-responsive liposomes as nanocarriers for the delivery of the anti-glioma agent TRAM-34

2021 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Naziris, N.; Pippa, N.; Sereti, E.; Chrysostomou, V.; Kedzierska, M.; Kajdanek, J.; Ionov, M.; Milowska, K.; Balcerzak, L.; Garofalo, S.; Limatola, C.; Pispas, S.; Dimas, K.; Bryszewska, M.; Demetzos, C.

Sex-specific behavioural deficits induced at early life by prenatal exposure to the cannabinoid receptor agonist WIN55, 212-2 depend on mGlu5 receptor signalling

2020 - BRITISH JOURNAL OF PHARMACOLOGY

Manduca, Antonia; Servadio, Michela; Melancia, Francesca; Schiavi, Sara; Manzoni, Olivier J; Trezza, Viviana

Optimization by response surface methodology of a dispersive magnetic solid phase extraction exploiting magnetic graphene nanocomposite coupled with UHPLC-PDA for simultaneous determination of new oral anticoagulants (NAOs) in human plasma

2020 - JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Ferrone, V.; Todaro, S.; Carlucci, M.; Fontana, A.; Ventrella, A.; Carlucci, G.; Milanetti, E.

Persistence on apixaban in atrial fibrillation patients. a retrospective multicentre study

2019 - JOURNAL OF CARDIOVASCULAR MEDICINE

Verdecchia, Paolo; D'Onofrio, Antonio; Russo, Vincenzo; Fedele, Francesco; Adamo, Francesco; Benedetti, Giulia; Ferrante, Fabio; Lodigiani, Corrado; Paciullo, Francesco; Aita, Adolfo; Bartolini, Claudia; Molini, Maria Gabriella; Di Lenarda, Andrea; Mazzone, Carmine; Scotti, Lorenza; Lanati, Elena Paola; Iorio, Arianna

Real-world efficacy and safety of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation

2019 - INTERNAL AND EMERGENCY MEDICINE

Violi, F.; Pastori, D.

Functional estrogen receptors of red blood cells. Do they influence intracellular signaling?

2019 - CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Vona, R.; Gambardella, L.; Ortona, E.; Santulli, M.; Malorni, W.; Care, A.; Pietraforte, D.; Straface, E.

Apixaban interacts with haemoglobin: effects on its plasma levels

2018 - THROMBOSIS AND HAEMOSTASIS

Sacco, Monica; Lancellotti, Stefano; Berruti, Federico; Arcovito, Alessandro; Bellelli, Andrea; Ricciardelli, Tiziana; Autiero, Ida; Cavallo, Luigi; Oliva, Romina; De Cristofaro, Raimondo

Enhancing activity and selectivity in a series of pyrrol-1-yl-1-hydroxypyrazole-based aldose reductase inhibitors: the case of trifluoroacetylation

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Papastavrou, Nikolaos; Chatzopoulou, Maria; Ballekova, Jana; Cappiello, Mario; Moschini, Roberta; Balestri, Francesco; Patsilinakos, Alexandros; Ragno, Rino; Stefek, Milan; Nicolaou, Ioannis

Italian intersociety consensus on DOAC use in internal medicine

2017 - INTERNAL AND EMERGENCY MEDICINE

Prisco, D.; Ageno, W.; Becattini, C.; D'Angelo, A.; Davi, G.; De Cristofaro, R.; Dentali, F.; Di Minno, G.; Falanga, A.; Gussoni, G.; Masotti, L.; Palareti, G.; Pignatelli, P.; Santi, R. M.; Santilli, F.; Silingardi, M.; Tufano, A.; Violi, F.

Desymmetrization of cyclopentenediones via organocatalytic cross-dehydrogenative coupling

2017 - ADVANCED SYNTHESIS & CATALYSIS

Vetica, Fabrizio; Bailey, Stephen; Chauhan, Pankaj; Turberg, Mathias; Ghaur, Adjmal; Raabe, Gerhard; Enders, Dieter

Eltrombopag versus placebo for low-risk myelodysplastic syndromes with thrombocytopenia (EQoL-MDS): phase 1 results of a single-blind, randomised, controlled, phase 2 superiority trial

2017 - THE LANCET. HAEMATOLOGY

Oliva, Esther N; Alati, Caterina; Santini, Valeria; Poloni, Antonella; Molteni, Alfredo; Niscola, Pasquale; Salvi, Flavia; Sanpaolo, Grazia; Balleari, Enrico; Germing, Ulrich; Fenaux, Pierre; Stamatoullas, Aspasia; Palumbo, Giuseppe A; Salutari, Prassede; Impera, Stefana; Avanzini, Paolo; Cortelezzi, Agostino; Liberati, Anna Marina; Carluccio, Paola; Buccisano, Francesco; Voso, Maria Teresa; Mancini, Stefano; Kulasekararaj, Austin; Morabito, Fortunato; Bocchia, Monica; Cufari, Patrizia; Spiriti, Maria Antonietta Aloe; Santacaterina, Irene; D'Errigo, Maria Grazia; Bova, Irene; Zini, Gina; Latagliata, Roberto

The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases

2016 - BIOCHEMICAL PHARMACOLOGY

Van Den Bosch, Thea; Boichenko, Alexander; Leus, Niek G. J.; Ourailidou, Maria E.; Wapenaar, Hannah; Rotili, Dante; Mai, Antonello; Imhof, Axel; Bischoff, Rainer; Haisma, Hidde J.; Dekker, Frank J.

Antidotes to non-vitamin K oral anticoagulants: Necessary or not?

2015 - EXPERT OPINION ON PHARMACOTHERAPY

Proietti, Marco; Lip, Gregory Y. H.

Ibrutinib as initial therapy for patients with chronic lymphocytic leukemia

2015 - NEW ENGLAND JOURNAL OF MEDICINE

Burger, Ja; Tedeschi, A; Barr, Pm; Robak, T; Owen, C; Ghia, P; Bairey, O; Hillmen, P; Bartlett, Nl; Li, J; Simpson, D; Grosicki, S; Devereux, S; Mccarthy, H; Coutre, S; Quach, H; Gaidano, G; Maslyak, Z; Stevens, Da; Janssens, A; Offner, F; Mayer, J; O'Dwyer, M; Hellmann, A; Schuh, A; Siddiqi, T; Polliack, A; Tam, Cs; Keating, M; Kipps, Tj; Jen, J; Jindra, P; SimkoviÄ, M; Braester, A; Ruchlemer, R; Foa, Roberto; Semenzato, G; Hawkins, T; Atanasio, Cm; Demirkan, F; Kaynar, L; Pylypenko, H; Fox, C; Thirman, M; Campbell, P; Coughlin, P; Harrup, R; Kuss, B; Turner, P; Wu, Kl; Larratt, L; Fineman, R; Marasca, R; Zinzani, Pl; Corbett, G; Abrisqueta, P; Delgado, J; GonzÃ¡lez Barca, E; de Oteyza, Jp; Arsland, O; Kaplan, P; Oliynyk, H; Hamblin, M; Atkins, J; Barrientos, J; Gasic, S; Hou, Jz; Kingsley, E; Shadman, M; Badoux, X; Gill, D; Opat, S; Bron, D; Van Den Neste, E; Jing, H; Zhu, J; Vandenberghe, E; Tadmor, T; Cortelezzi, A; Ganly, P; Weinkove, R; Pluta, A; Pristupa, A; GarcÃa Marco, Ja; Vural, F; YaÄci, M; Kasych, M; Duncombe, A; Fegan, C; Quackenbush, R; Tirumali, N.

Widespread renal polycystosis induced by crizotinib

2015 - TUMORI

DI GIROLAMO, Marco; Paris, Ida; Carbonetti, Francesco; Onesti, Elisa Concetta; Socciarelli, Fabio; Marchetti, Paolo

Change of right heart size and function by long-term therapy with riociguat in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension

2015 - INTERNATIONAL JOURNAL OF CARDIOLOGY

Marra, ALBERTO MARIA; Egenlauf, Benjamin; Ehlken, Nicola; Fischer, Christine; Eichstaedt, Christina; Nagel, Christian; Bossone, Eduardo; Cittadini, Antonio; Halank, Michael; Gall, Henning; Olsson, Karen M; Lange, Tobias J; GrÃ¼nig, Ekkehard

Eruptive squamous cell carcinomas with keratoacanthoma-like features in a patient treated with ruxolitinib

2015 - BRITISH JOURNAL OF DERMATOLOGY

Fabiano, A.; Calzavara-Pinton, P.; Monari, P.; Moggio, E.; Pellacani, G.; Manganoni, A. M.; Gualdi, G.

Economic assessment of eltrombopag in the treatment of thrombocytopenia

2015 - EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH

Romano, F.; Ruggeri, M.; Coretti, S.; Giannini, E. G.; Sacchini, D.; Annichiarico, B. E.; Marchetti, M.; Rodeghiero, F.; Lidonnici, D.