Pubblicazioni

Human estrogen receptor Î± antagonists, part 2: Synthesis driven by rational design, in vitro antiproliferative, and in vivo anticancer evaluation of innovative coumarin-related antiestrogens as breast cancer suppressants

2022 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Kurtanovic, N.; Tomasevic, N.; Matic, S.; Mitrovic, M. M.; Kostic, D. A.; Sabatino, M.; Antonini, L.; Ragno, R.; Mladenovic, M.

6-Fluorophenylbenzohydrazides inhibit Mycobacterium tuberculosis growth through alteration of tryptophan biosynthesis

2021 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Consalvi, S.; Venditti, G.; Zhu, J.; Boshoff, H. I.; Arora, K.; De Logu, A.; Ioerger, T. R.; Rubin, E. J.; Biava, M.; Poce, G.

Efficient synthesis and first regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold and their evaluation in H2O2-induced oxidative stress

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Loubidi, Mohammed; Jouha, Jabrane; Tber, Zahira; Khouili, Mostafa; Suzenet, Franck; Akssira, Mohamed; Erdogan, MÃ¼min Alper; KÃ¶se, Fadime AydÄ±n; DagcÄ±, Taner; Armagan, GÃ¼liz; Saso, Luciano; Guillaumet, GÃ©rald

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Talapatra, Sandeep K.; Tham, Chuin Lean; Guglielmi, Paolo; Cirilli, Roberto; Chandrasekaran, Balakumar; Karpoormath, Rajshekhar; Carradori, Simone; Kozielski, Frank

Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: evaluation of antimicrobial, cytotoxic and hemolytic activities

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Merlino, Francesco; Carotenuto, Alfonso; Casciaro, Bruno; Martora, Francesca; Loffredo, MARIA ROSA; DI GRAZIA, Antonio; Yousif, Ali M.; Brancaccio, Diego; Palomba, Luciana; Novellino, Ettore; Galdiero, Massimiliano; Iovene, Maria Rosaria; Mangoni, Maria Luisa; Grieco, Paolo

Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the Î±3Î²4 nicotinic acetylcholine receptor subtype

2016 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Matera, Carlo; Quadri, Marta; Sciaccaluga, Miriam; PomÃ¨, Diego Yuri; Fasoli, Francesca; De Amici, Marco; Fucile, Sergio; Gotti, Cecilia; Dallanoce, Clelia; Grazioso, Giovanni

Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions

2016 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Drinkwater, Nyssa; Vinh, Natalie B.; Mistry, Shailesh N.; Bamert, Rebecca S.; Ruggeri, Chiara; Holleran, John P.; Loganathan, Sasdekumar; Paiardini, Alessandro; Charman, Susan A.; Powell, Andrew K.; Avery, Vicky M.; Mcgowan, Sheena; Scammells, Peter J.

Enzyme kinetics and inhibition of histone acetyltransferase KAT8

2015 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Wapenaar, Hannah; van der Wouden, Petra E; Groves, Matthew R; Rotili, Dante; Mai, Antonello; Dekker, Frank J.