Pubblicazioni

Glucocorticoids rescue cell surface trafficking of R451C Neuroligin3 and enhance synapse formation

2024 - TRAFFIC

Diamanti, T.; Trobiani, L.; Mautone, L.; Serafini, F.; Gioia, R.; Ferrucci, L.; Lauro, C.; Bianchi, S.; Perfetto, C.; Guglielmo, S.; Sollazzo, R.; Giorda, E.; Setini, A.; Ragozzino, D.; Miranda, E.; Comoletti, D.; Di Angelantonio, S.; Cacci, E.; De Jaco, A.

The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells

2022 - BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Arena, A.; Romeo, M. A.; Benedetti, R.; Gilardini Montani, M. S.; Cirone, M.

The disturbance of protein synthesis/degradation homeostasis is a common trait of age-related neurodegenerative disorders

2022 - ADVANCES IN PROTEIN CHEMISTRY AND STRUCTURAL BIOLOGY

DI DOMENICO, Fabio; Di Domenico, F; Lanzillotta, C

Broad kinase inhibition mitigates early neuronal dysfunction in tauopathy

2021 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Koren, Shon A; Hamm, Matthew J; Cloyd, Ryan; Fontaine, Sarah N; Chishti, Emad; Lanzillotta, Chiara; Rodriguez-Rivera, Jennifer; Ingram, Alexandria; Bell, Michelle; Galvis-Escobar, Sara M; Zulia, Nicholas; Di Domenico, Fabio; Duong, Duc; Seyfried, Nicholas T; Powell, David; Vandsburger, Moriel; Frolinger, Tal; Hartz, Anika M S; Koren, John; Axten, Jeffrey M; Laping, Nicholas J; Abisambra, Jose F

Stress responses in down syndrome neurodegeneration: State of the art and therapeutic molecules

2021 - BIOMOLECULES

Lanzillotta, C.; Di Domenico, F.

Oncogenic pathways activated by pro-inflammatory cytokines promote mutant p53 stability: clue for novel anticancer therapies

2021 - CELLULAR AND MOLECULAR LIFE SCIENCES

D'Orazi, G.; Cordani, M.; Cirone, M.

The unfolded protein response in amyotrophic later sclerosis. results of a phase 2 trial

2021 - BRAIN

Bella, Eleonora Dalla; Bersano, Enrica; Antonini, Giovanni; Borghero, Giuseppe; Capasso, Margherita; Caponnetto, Claudia; ChiÃ², Adriano; Corbo, Massimo; Filosto, Massimiliano; Giannini, Fabio; Spataro, Rossella; Lunetta, Christian; Mandrioli, Jessica; Messina, Sonia; MonsurrÃ², Maria Rosaria; Mora, Gabriele; Riva, Nilo; Rizzi, Romana; Siciliano, Gabriele; Silani, Vincenzo; Simone, Isabella; SorarÃ¹, Gianni; Tugnoli, Valeria; Verriello, Lorenzo; Volanti, Paolo; Furlan, Roberto; Nolan, John M; Abgueguen, Emmanuelle; Tramacere, Irene; Lauria, Giuseppe

Chronic perk induction promotes alzheimer-like neuropathology in down syndrome: Insights for therapeutic intervention

2020 - PROGRESS IN NEUROBIOLOGY

Lanzillotta, C.; Zuliani, I.; Tramutola, A.; Barone, E.; Blarzino, C.; Folgiero, V.; Caforio, M.; Valentini, D.; Villani, A.; Locatelli, F.; Butterfield, D. A.; Head, E.; Perluigi, M.; Abisambra, J. F.; Di Domenico, F.

Proteomics study of peripheral blood mononuclear cells in down syndrome children

2020 - ANTIOXIDANTS

Lanzillotta, C.; Greco, V.; Valentini, D.; Villani, A.; Folgiero, V.; Caforio, M.; Locatelli, F.; Pagnotta, S.; Barone, E.; Urbani, A.; Domenico, F. D.; Perluigi, M.

Autophagy manipulation as a strategy for efficient anticancer therapies: possible consequences

2019 - JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cirone, M.; Gilardini Montani, M. S.; Granato, M.; Garufi, A.; Faggioni, A.; D'Orazi, G.

Early and selective activation and subsequent alterations to the unfolded protein response in down syndrome mouse models

2018 - JOURNAL OF ALZHEIMER'S DISEASE

Lanzillotta, Chiara; Tramutola, Antonella; Meier, Shelby; Schmitt, Frederick; Barone, Eugenio; Perluigi, Marzia; Di Domenico, Fabio; Abisambra, Jose F

UPR activation specifically modulates glutamate neurotransmission in the cerebellum of a mouse model of autism

2018 - NEUROBIOLOGY OF DISEASE

Trobiani, L.; Favaloro, Fl.; Di Castro, Ma.; Di Mattia, M.; Cariello, M.; Miranda, E.; Canterini, S.; De Stefano, Me.; Comoletti, D.; Limatola, C.; De Jaco, A.

Endothelial cells, endoplasmic reticulum stress and oxysterols

2017 - REDOX BIOLOGY

Luchetti, F; Crinelli, R.; Cesarini, E.; Canonico, B.; Guidi, L.; Zerbinati, C.; Di Sario, G.; Zamai, L.; Magnani, M.; Papa, S.; Iuliano, Luigi

Protein misfolding, amyotrophic lateral sclerosis and guanabenz. Protocol for a phase II RCT with futility design (ProMISe trial)

2017 - BMJ OPEN

Bella, Eleonora Dalla; Tramacere, Irene; Antonini, Giovanni; Borghero, Giuseppe; Capasso, Margherita; Caponnetto, Claudia; ChiÃ², Adriano; Corbo, Massimo; Eleopra, Roberto; Filosto, Massimiliano; Giannini, Fabio; Granieri, Enrico; Bella, Vincenzo La; Lunetta, Christian; Mandrioli, Jessica; Mazzini, Letizia; Messina, Sonia; MonsurrÃ², Maria Rosaria; Mora, Gabriele; Riva, Nilo; Rizzi, Romana; Siciliano, Gabriele; Silani, Vincenzo; Simone, Isabella; SorarÃ¹, Gianni; Volanti, Paolo; Lauria, Giuseppe

Endoplasmic reticulum stress, unfolded protein response, and cancer cell fate

2017 - FRONTIERS IN ONCOLOGY

Corazzari, M.; Gagliardi, M.; Fimia, G. M.; Piacentini, M.

Autism-associated R451C mutation in neuroligin3 leads to activation of the unfolded protein response in a PC12 Tet-On inducible system

2016 - BIOCHEMICAL JOURNAL

Ulbrich, Lisa; Favaloro, FLORES LIETTA; Trobiani, Laura; Marchetti, Valentina; Patel, Vruti; Pascucci, Tiziana; Comoletti, Davide; Marciniak, Stefan J.; DE JACO, Antonella

OSAS-Related inflammatory mechanisms of liver injury in nonalcoholic fatty liver disease

2015 - MEDIATORS OF INFLAMMATION

Paschetta, E; Belci, P; Alisi, A; Liccardo, D; Cutrera, R; Musso, G; Nobili, V.

Targeting BAG-1: a novel strategy to increase drug efficacy in acute myeloid leukemia

2015 - EXPERIMENTAL HEMATOLOGY

Aveic, S.; Viola, G.; Accordi, B.; Micalizzi, C.; Santoro, N.; Masetti, R.; Locatelli, F.; Basso, G.; Pigazzi, M.