Pubblicazioni

Azidothymidine "clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors

2020 - JOURNAL OF MEDICINAL CHEMISTRY
Berrino, E.; Angeli, A.; Zhdanov, D. D.; Kiryukhina, A. P.; Milaneschi, A.; De Luca, A.; Bozdag, M.; Carradori, S.; Selleri, S.; Bartolucci, G.; Peat, T. S.; Ferraroni, M.; Supuran, C. T.; Carta, F.

1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors

2020 - JOURNAL OF MEDICINAL CHEMISTRY
D'Ascenzio, M.; Secci, D.; Carradori, S.; Zara, S.; Guglielmi, P.; Cirilli, R.; Pierini, M.; Poli, G.; Tuccinardi, T.; Angeli, A.; Supuran, C. T.

Phenyl(thio)phosphon(amid)ate benzenesulfonamides as potent and selective inhibitors of human carbonic anhydrases II and VII counteract allodynia in a mouse model of oxaliplatin-induced neuropathy

2020 - JOURNAL OF MEDICINAL CHEMISTRY
Nocentini, A.; Alterio, V.; Bua, S.; Micheli, L.; Esposito, D.; Buonanno, M.; Bartolucci, G.; Osman, S. M.; ALOthman, Z. A.; Cirilli, R.; Pierini, M.; Monti, S. M.; Di Cesare Mannelli, L.; Gratteri, P.; Ghelardini, C.; De Simone, G.; Supuran, C. T.

Insights into pparγphosphorylation and its inhibition mechanism

2020 - JOURNAL OF MEDICINAL CHEMISTRY
Montanari, R.; Capelli, D.; Yamamoto, K.; Awaishima, H.; Nishikata, K.; Barendregt, A.; Heck, A. J. R.; Loiodice, F.; Altieri, F.; Paiardini, A.; Grottesi, A.; Pirone, L.; Pedone, E.; Peiretti, F.; Brunel, J. M.; Itoh, T.; Pochetti, G.

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

2020 - JOURNAL OF MEDICINAL CHEMISTRY
Viayna, Elisabet; Coquelle, Nicolas; Cieslikiewicz-Bouet, Monika; Cisternas, Pedro; Oliva, Carolina A.; Sánchez-López, Elena; Ettcheto, Miren; Bartolini, Manuela; De Simone, Angela; Ricchini, Mattia; Rendina, Marisa; Pons, Mégane; Firuzi, Omidreza; Pérez, Belén; Saso, Luciano; Andrisano, Vincenza; Nachon, Florian; Brazzolotto, Xavier; García, Maria Luisa; Camins, Antoni; Silman, Israel; Jean, Ludovic; Inestrosa, Nibaldo C.; Colletier, Jacques-Philippe; Renard, Pierre-Yves; Muñoz-Torrero, Diego

Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent α4β2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the α3β4 Subtype

2020 - JOURNAL OF MEDICINAL CHEMISTRY
Bavo, Francesco; Pallavicini, Marco; Gotti, Cecilia; Appiani, Rebecca; Moretti, Milena; Colombo, Sara Francesca; Pucci, Susanna; Viani, Paola; Budriesi, Roberta; Renzi, Massimiliano; Fucile, Sergio; Bolchi, Cristiano

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