Indeterminate thyroid nodules (TIR3A/TIR3B) according to the new Italian Reporting System for Thyroid Cytology: a cytomorphological study
OBJECTIVE:
The Italian reporting system for thyroid cytology classifies indeterminate lesions as TIR3A (low-risk) or TIR3B (high-risk) and is meant to provide practical guidance rather than a detailed consideration of morphological features. We aimed to assess which cytological features have the most diagnostic value and whether they are effective in classifying nodules as either TIR3A or TIR3B and in predicting histological outcomes.