Speranza Donatella Rubattu

Pubblicazioni

Titolo Pubblicato in Anno
The role of genetic testing in suspected fulminant myocarditis: A case report MOLECULAR GENETICS AND METABOLISM REPORTS 2023
Polymorphic variants at NDUFC2, encoding a mitochondrial complex I subunit, associate with cardiac hypertrophy in human hypertension MOLECULAR MEDICINE 2023
Effects of two-month treatment with a mixture of natural activators of autophagy on oxidative stress and arterial stiffness in patients with essential hypertension: A pilot study NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES 2023
MST1 mediates doxorubicin-induced cardiomyopathy by SIRT3 downregulation CELLULAR AND MOLECULAR LIFE SCIENCES 2023
Abnormal expression of sphingolipid-metabolizing enzymes in the heart of spontaneously hypertensive rat models BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 2023
BNP/NT-proBNP levels are sensitive markers of impaired prognosis in patients without heart failure JACC. ADVANCES 2023
The natriuretic peptides for hypertension treatment HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION 2022
The impact of autophagy modulation on phenotype and survival of cardiac stromal cells under metabolic stress CELL DEATH DISCOVERY 2022
Role of Uncoupling Protein 2 Gene Polymorphisms on the Risk of Ischemic Stroke in a Sardinian Population LIFE 2022
Editorial: Natriuretic Peptides in Cardiovascular Pathophysiology FRONTIERS IN PHYSIOLOGY 2022
Impact of a NDUFC2 Variant on the Occurrence of Acute Coronary Syndromes FRONTIERS IN CARDIOVASCULAR MEDICINE 2022
Angiotensin Receptor Blockers in the Management of Hypertension: A Real-World Perspective and Current Recommendations VASCULAR HEALTH AND RISK MANAGEMENT 2022
Natural Activators of Autophagy Increase Maximal Walking Distance and Reduce Oxidative Stress in Patients with Peripheral Artery Disease: A Pilot Study ANTIOXIDANTS 2022
Endocrine functions of the heart: from bench to bedside EUROPEAN HEART JOURNAL 2022
Circulating NT-proANP level is a predictor of mortality for systemic sclerosis: a retrospective study of an Italian cohort EXPERT REVIEW OF CLINICAL IMMUNOLOGY 2021
TNNI3 and KCNQ1 co-inherited variants in a family with hypertrophic cardiomyopathy and long QT phenotypes: A case report MOLECULAR GENETICS AND METABOLISM REPORTS 2021
Beneficial effects of a combination of natural product activators of autophagy on endothelial cells and platelets BRITISH JOURNAL OF PHARMACOLOGY 2021
Strategies to improve blood pressure control: A step forward to winning the battle INTERNATIONAL JOURNAL OF CARDIOLOGY. HYPERTENSION 2021
Uncoupling Protein 2 as a pathogenic determinant and therapeutic target in cardiovascular and metabolic diseases CURRENT NEUROPHARMACOLOGY 2021
Differential Expression of Sphingolipid Metabolizing Enzymes in Spontaneously Hypertensive Rats: A Possible Substrate for Susceptibility to Brain and Kidney Damage INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021

ERC

  • LS4_10

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

Renin-angiotensin-aldosterone system: systemic and tissue systems and their role in arterial hypertension.

Characterization of an animal model of arterial hypertension and target organ damage (the stroke-prone spontaneously hypertensive rat).

Molecular-genetic bases of target organ damage in hypertension (stroke, cardiac hypertrophy, renal damage) in an animal model and in humans.

Characterization of atrial natriuretic factor as a risk factor for cardiovascular diseases in the animal model and in humans.

Analysis of mitochondrial dysfunction as a molecular mechanism of hypertensive organ damage in an animal model and in humans.

Role of autophagy and mitophagy in cardiovascular diseases.

 

Keywords

cardiovascular diseases
molecular mechanisms
animal models
mitochondria
natriuretic peptides
oxidative stress
genetics
autophagy
mitophagy

Gruppi di ricerca

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