Speranza Donatella Rubattu


Titolo Pubblicato in Anno
Beneficial effects of a combination of natural product activators of autophagy on endothelial cells and platelets BRITISH JOURNAL OF PHARMACOLOGY 2021
Strategies to improve blood pressure control: A step forward to winning the battle INTERNATIONAL JOURNAL OF CARDIOLOGY. HYPERTENSION 2021
Uncoupling Protein 2 as a pathogenic determinant and therapeutic target in cardiovascular and metabolic diseases CURRENT NEUROPHARMACOLOGY 2021
Differential Expression of Sphingolipid Metabolizing Enzymes in Spontaneously Hypertensive Rats: A Possible Substrate for Susceptibility to Brain and Kidney Damage INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
The ATP synthase glycine zipper of the c subunits: from the structural to the functional role in mitochondrial biology of cardiovascular diseases BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 2021
A Contemporary View of Natriuretic Peptides in the SARS-CoV-2 Era FRONTIERS IN PHYSIOLOGY 2021
Trehalose, a natural disaccharide, reduces stroke occurrence in the stroke-prone spontaneously hypertensive rat PHARMACOLOGICAL RESEARCH 2021
Novel Imaging and Genetic Risk Markers in Takotsubo Syndrome FRONTIERS IN CARDIOVASCULAR MEDICINE 2021
An interplay between UCP2 and ROS protects cells from high-salt-induced injury through autophagy stimulation CELL DEATH & DISEASE 2021
Relevance of stromal interaction molecule 1 (STIM1) in experimental and human stroke PFLÜGERS ARCHIV 2021
Novel ANP (Atrial Natriuretic Peptide) based therapy for hypertension: the promising role of a disease mechanism targeted approach HYPERTENSION 2021
Targeting cyclic guanylate monophosphate in resistant hypertension and heart failure. Are sacubitril/valsartan and vericiguat synergistic and effective in both conditions? HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION 2021
[Prevention Italy 2021 - An update of the 2018 Consensus document and recommendations for the prevention of cardiovascular disease in Italy] GIORNALE ITALIANO DI CARDIOLOGIA 2021
BNP level and post-transcatheter aortic valve replacement outcome: an intriguing J-shaped relationship EUROPEAN HEART JOURNAL 2020
Pathogenesis of ischemic stroke: role of epigenetic mechanisms GENES 2020
Functional Role of Natriuretic Peptides in Risk Assessment and Prognosis of Patients with Mitral Regurgitation JOURNAL OF CLINICAL MEDICINE 2020
Risk stratification in hypertrophic cardiomyopathy. Insights from genetic analysis and cardiopulmonary exercise testing JOURNAL OF CLINICAL MEDICINE 2020
Vascular ageing in hypertension. focus on mitochondria MECHANISMS OF AGEING AND DEVELOPMENT 2020
The role of mitochondrial dynamics in cardiovascular diseases BRITISH JOURNAL OF PHARMACOLOGY 2020
Epigenetic control of natriuretic peptides: implications for health and disease CELLULAR AND MOLECULAR LIFE SCIENCES 2020


  • LS4_10


  • Life-science technologies & biotechnologies

Interessi di ricerca

Renin-angiotensin-aldosterone system: systemic and tissue systems and their role in arterial hypertension.

Characterization of an animal model of arterial hypertension and target organ damage (the stroke-prone spontaneously hypertensive rat).

Molecular-genetic bases of target organ damage in hypertension (stroke, cardiac hypertrophy, renal damage) in an animal model and in humans.

Characterization of atrial natriuretic factor as a risk factor for cardiovascular diseases in the animal model and in humans.

Analysis of mitochondrial dysfunction as a molecular mechanism of hypertensive organ damage in an animal model and in humans.

Role of autophagy and mitophagy in cardiovascular diseases.



cardiovascular diseases
molecular mechanisms
animal models
natriuretic peptides
oxidative stress

Gruppi di ricerca

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