Speranza Donatella Rubattu


Titolo Pubblicato in Anno
Brain overexpression of uncoupling protein-2 (UCP2) delays renal damage and stroke occurrence in stroke-prone spontaneously hypertensive rats INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Blockade of the neurohormonal systems in heart failure with preserved ejection fraction. A contemporary meta-analysis INTERNATIONAL JOURNAL OF CARDIOLOGY 2020
Natriuretic Peptides, Cognitive Impairment and Dementia. An Intriguing Pathogenic Link with Implications in Hypertension JOURNAL OF CLINICAL MEDICINE 2020
Recommendations for Cardiovascular Prevention During the Sars-Cov-2 Pandemic. An Executive Document by the Board of the Italian Society of Cardiovascular Prevention HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION 2020
Role of DAMPs and of Leukocytes Infiltration in Ischemic Stroke: Insights from Animal Models and Translation to the Human Disease CELLULAR AND MOLECULAR NEUROBIOLOGY 2020
Sacubitril/Valsartan: Potential Impact of ARNi "Beyond the Wall" of ACE2 on Treatment and Prognosis of Heart Failure Patients With Coronavirus Disease-19 FRONTIERS IN CARDIOVASCULAR MEDICINE 2020
T2238C atrial natriuretic peptide gene variant and cardiovascular events in patients with atrial fibrillation: A substudy from the ATHERO-AF cohort INTERNATIONAL JOURNAL OF CARDIOLOGY 2020
A novel promising frontier for human health: The beneficial effects of nutraceuticals in cardiovascular diseases INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Inhibition of miR-155 Attenuates Detrimental Vascular Effects of Tobacco Cigarette Smoking JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE 2020
Molecular Implications of natriuretic peptides in the protection from hypertension and target organ damage development INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019
The reduction of NDUFC2 expression is associated with mitochondrial impairment in circulating mononuclear cells of patients with acute coronary syndrome INTERNATIONAL JOURNAL OF CARDIOLOGY 2019
Mitochondrial complex I deficiency and cardiovascular diseases. current evidence and future directions JOURNAL OF MOLECULAR MEDICINE 2019
Molecular and clinical implications of natriuretic peptides in aortic valve stenosis JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 2019
Hypertension in the elderly. Which are the blood pressure threshold values? EUROPEAN HEART JOURNAL SUPPLEMENTS 2019
ARNi: A Novel Approach to Counteract Cardiovascular Diseases INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019
Natriuretic Peptides in the Cardiovascular System. Multifaceted Roles in Physiology, Pathology and Therapeutics INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019
Atrial natriuretic peptide predicts disease progression and digital ulcers development in systemic sclerosis patients JOURNAL OF CARDIOVASCULAR MEDICINE 2019
Circulating leukocytes and oxidative Stress in cardiovascular diseases. a state of the art OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 2019
Pharmacological restoration of autophagy reduces hypertension-related stroke occurrence AUTOPHAGY 2019
The T2238C human atrial natriuretic peptide molecular variant and the risk of cardiovascular diseases INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2018


  • LS4_10


  • Life-science technologies & biotechnologies

Interessi di ricerca

Renin-angiotensin-aldosterone system: systemic and tissue systems and their role in arterial hypertension.

Characterization of an animal model of arterial hypertension and target organ damage (the stroke-prone spontaneously hypertensive rat).

Molecular-genetic bases of target organ damage in hypertension (stroke, cardiac hypertrophy, renal damage) in an animal model and in humans.

Characterization of atrial natriuretic factor as a risk factor for cardiovascular diseases in the animal model and in humans.

Analysis of mitochondrial dysfunction as a molecular mechanism of hypertensive organ damage in an animal model and in humans.

Role of autophagy and mitophagy in cardiovascular diseases.



cardiovascular diseases
molecular mechanisms
animal models
natriuretic peptides
oxidative stress

Gruppi di ricerca

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma