Speranza Donatella Rubattu | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Targeting cyclic guanylate monophosphate in resistant hypertension and heart failure. Are sacubitril/valsartan and vericiguat synergistic and effective in both conditions?	HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION	2021
[Prevention Italy 2021 - An update of the 2018 Consensus document and recommendations for the prevention of cardiovascular disease in Italy]	GIORNALE ITALIANO DI CARDIOLOGIA	2021
BNP level and post-transcatheter aortic valve replacement outcome: an intriguing J-shaped relationship	EUROPEAN HEART JOURNAL	2020
Pathogenesis of ischemic stroke: role of epigenetic mechanisms	GENES	2020
Functional Role of Natriuretic Peptides in Risk Assessment and Prognosis of Patients with Mitral Regurgitation	JOURNAL OF CLINICAL MEDICINE	2020
Risk stratification in hypertrophic cardiomyopathy. Insights from genetic analysis and cardiopulmonary exercise testing	JOURNAL OF CLINICAL MEDICINE	2020
Vascular ageing in hypertension. focus on mitochondria	MECHANISMS OF AGEING AND DEVELOPMENT	2020
The role of mitochondrial dynamics in cardiovascular diseases	BRITISH JOURNAL OF PHARMACOLOGY	2020
Epigenetic control of natriuretic peptides: implications for health and disease	CELLULAR AND MOLECULAR LIFE SCIENCES	2020
Brain overexpression of uncoupling protein-2 (UCP2) delays renal damage and stroke occurrence in stroke-prone spontaneously hypertensive rats	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2020
Blockade of the neurohormonal systems in heart failure with preserved ejection fraction. A contemporary meta-analysis	INTERNATIONAL JOURNAL OF CARDIOLOGY	2020
Natriuretic Peptides, Cognitive Impairment and Dementia. An Intriguing Pathogenic Link with Implications in Hypertension	JOURNAL OF CLINICAL MEDICINE	2020
Recommendations for Cardiovascular Prevention During the Sars-Cov-2 Pandemic. An Executive Document by the Board of the Italian Society of Cardiovascular Prevention	HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION	2020
Role of DAMPs and of Leukocytes Infiltration in Ischemic Stroke: Insights from Animal Models and Translation to the Human Disease	CELLULAR AND MOLECULAR NEUROBIOLOGY	2020
Sacubitril/Valsartan: Potential Impact of ARNi "Beyond the Wall" of ACE2 on Treatment and Prognosis of Heart Failure Patients With Coronavirus Disease-19	FRONTIERS IN CARDIOVASCULAR MEDICINE	2020
T2238C atrial natriuretic peptide gene variant and cardiovascular events in patients with atrial fibrillation: A substudy from the ATHERO-AF cohort	INTERNATIONAL JOURNAL OF CARDIOLOGY	2020
A novel promising frontier for human health: The beneficial effects of nutraceuticals in cardiovascular diseases	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2020
Inhibition of miR-155 Attenuates Detrimental Vascular Effects of Tobacco Cigarette Smoking	JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE	2020
Molecular Implications of natriuretic peptides in the protection from hypertension and target organ damage development	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2019
The reduction of NDUFC2 expression is associated with mitochondrial impairment in circulating mononuclear cells of patients with acute coronary syndrome	INTERNATIONAL JOURNAL OF CARDIOLOGY	2019

ERC

LS4_10

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Renin-angiotensin-aldosterone system: systemic and tissue systems and their role in arterial hypertension.

Characterization of an animal model of arterial hypertension and target organ damage (the stroke-prone spontaneously hypertensive rat).

Molecular-genetic bases of target organ damage in hypertension (stroke, cardiac hypertrophy, renal damage) in an animal model and in humans.

Characterization of atrial natriuretic factor as a risk factor for cardiovascular diseases in the animal model and in humans.

Analysis of mitochondrial dysfunction as a molecular mechanism of hypertensive organ damage in an animal model and in humans.

Role of autophagy and mitophagy in cardiovascular diseases.

Keywords

cardiovascular diseases

molecular mechanisms

animal models

mitochondria

natriuretic peptides

oxidative stress

genetics

autophagy

mitophagy

Progetti di Ricerca

Gruppi di ricerca

Disregolazione neurormonale nelle malattie cardiovascolari

Disfunzione mitocondriale e stress ossidativo nelle malattie cardiovascolari