Speranza Donatella Rubattu | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
The natriuretic peptides for hypertension treatment	HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION	2022
The impact of autophagy modulation on phenotype and survival of cardiac stromal cells under metabolic stress	CELL DEATH DISCOVERY	2022
Role of Uncoupling Protein 2 Gene Polymorphisms on the Risk of Ischemic Stroke in a Sardinian Population	LIFE	2022
Editorial: Natriuretic Peptides in Cardiovascular Pathophysiology	FRONTIERS IN PHYSIOLOGY	2022
Impact of a NDUFC2 Variant on the Occurrence of Acute Coronary Syndromes	FRONTIERS IN CARDIOVASCULAR MEDICINE	2022
Angiotensin Receptor Blockers in the Management of Hypertension: A Real-World Perspective and Current Recommendations	VASCULAR HEALTH AND RISK MANAGEMENT	2022
Natural Activators of Autophagy Increase Maximal Walking Distance and Reduce Oxidative Stress in Patients with Peripheral Artery Disease: A Pilot Study	ANTIOXIDANTS	2022
Endocrine functions of the heart: from bench to bedside	EUROPEAN HEART JOURNAL	2022
Circulating NT-proANP level is a predictor of mortality for systemic sclerosis: a retrospective study of an Italian cohort	EXPERT REVIEW OF CLINICAL IMMUNOLOGY	2021
TNNI3 and KCNQ1 co-inherited variants in a family with hypertrophic cardiomyopathy and long QT phenotypes: A case report	MOLECULAR GENETICS AND METABOLISM REPORTS	2021
Beneficial effects of a combination of natural product activators of autophagy on endothelial cells and platelets	BRITISH JOURNAL OF PHARMACOLOGY	2021
Strategies to improve blood pressure control: A step forward to winning the battle	INTERNATIONAL JOURNAL OF CARDIOLOGY. HYPERTENSION	2021
Uncoupling Protein 2 as a pathogenic determinant and therapeutic target in cardiovascular and metabolic diseases	CURRENT NEUROPHARMACOLOGY	2021
Differential Expression of Sphingolipid Metabolizing Enzymes in Spontaneously Hypertensive Rats: A Possible Substrate for Susceptibility to Brain and Kidney Damage	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2021
The ATP synthase glycine zipper of the c subunits: from the structural to the functional role in mitochondrial biology of cardiovascular diseases	BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH	2021
A Contemporary View of Natriuretic Peptides in the SARS-CoV-2 Era	FRONTIERS IN PHYSIOLOGY	2021
Trehalose, a natural disaccharide, reduces stroke occurrence in the stroke-prone spontaneously hypertensive rat	PHARMACOLOGICAL RESEARCH	2021
Novel Imaging and Genetic Risk Markers in Takotsubo Syndrome	FRONTIERS IN CARDIOVASCULAR MEDICINE	2021
An interplay between UCP2 and ROS protects cells from high-salt-induced injury through autophagy stimulation	CELL DEATH & DISEASE	2021
Relevance of stromal interaction molecule 1 (STIM1) in experimental and human stroke	PFLÜGERS ARCHIV	2021

ERC

LS4_10

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Renin-angiotensin-aldosterone system: systemic and tissue systems and their role in arterial hypertension.

Characterization of an animal model of arterial hypertension and target organ damage (the stroke-prone spontaneously hypertensive rat).

Molecular-genetic bases of target organ damage in hypertension (stroke, cardiac hypertrophy, renal damage) in an animal model and in humans.

Characterization of atrial natriuretic factor as a risk factor for cardiovascular diseases in the animal model and in humans.

Analysis of mitochondrial dysfunction as a molecular mechanism of hypertensive organ damage in an animal model and in humans.

Role of autophagy and mitophagy in cardiovascular diseases.

Keywords

cardiovascular diseases

molecular mechanisms

animal models

mitochondria

natriuretic peptides

oxidative stress

genetics

autophagy

mitophagy

Progetti di Ricerca

Gruppi di ricerca

Disregolazione neurormonale nelle malattie cardiovascolari

Disfunzione mitocondriale e stress ossidativo nelle malattie cardiovascolari

Laboratori di ricerca

laboratorio di biochimica e genomica