Speranza Donatella Rubattu


Titolo Pubblicato in Anno
The natriuretic peptides for hypertension treatment HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION 2022
The impact of autophagy modulation on phenotype and survival of cardiac stromal cells under metabolic stress CELL DEATH DISCOVERY 2022
Role of Uncoupling Protein 2 Gene Polymorphisms on the Risk of Ischemic Stroke in a Sardinian Population LIFE 2022
Editorial: Natriuretic Peptides in Cardiovascular Pathophysiology FRONTIERS IN PHYSIOLOGY 2022
Impact of a NDUFC2 Variant on the Occurrence of Acute Coronary Syndromes FRONTIERS IN CARDIOVASCULAR MEDICINE 2022
Angiotensin Receptor Blockers in the Management of Hypertension: A Real-World Perspective and Current Recommendations VASCULAR HEALTH AND RISK MANAGEMENT 2022
Natural Activators of Autophagy Increase Maximal Walking Distance and Reduce Oxidative Stress in Patients with Peripheral Artery Disease: A Pilot Study ANTIOXIDANTS 2022
Endocrine functions of the heart: from bench to bedside EUROPEAN HEART JOURNAL 2022
Circulating NT-proANP level is a predictor of mortality for systemic sclerosis: a retrospective study of an Italian cohort EXPERT REVIEW OF CLINICAL IMMUNOLOGY 2021
TNNI3 and KCNQ1 co-inherited variants in a family with hypertrophic cardiomyopathy and long QT phenotypes: A case report MOLECULAR GENETICS AND METABOLISM REPORTS 2021
Beneficial effects of a combination of natural product activators of autophagy on endothelial cells and platelets BRITISH JOURNAL OF PHARMACOLOGY 2021
Strategies to improve blood pressure control: A step forward to winning the battle INTERNATIONAL JOURNAL OF CARDIOLOGY. HYPERTENSION 2021
Uncoupling Protein 2 as a pathogenic determinant and therapeutic target in cardiovascular and metabolic diseases CURRENT NEUROPHARMACOLOGY 2021
Differential Expression of Sphingolipid Metabolizing Enzymes in Spontaneously Hypertensive Rats: A Possible Substrate for Susceptibility to Brain and Kidney Damage INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
The ATP synthase glycine zipper of the c subunits: from the structural to the functional role in mitochondrial biology of cardiovascular diseases BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 2021
A Contemporary View of Natriuretic Peptides in the SARS-CoV-2 Era FRONTIERS IN PHYSIOLOGY 2021
Trehalose, a natural disaccharide, reduces stroke occurrence in the stroke-prone spontaneously hypertensive rat PHARMACOLOGICAL RESEARCH 2021
Novel Imaging and Genetic Risk Markers in Takotsubo Syndrome FRONTIERS IN CARDIOVASCULAR MEDICINE 2021
An interplay between UCP2 and ROS protects cells from high-salt-induced injury through autophagy stimulation CELL DEATH & DISEASE 2021
Relevance of stromal interaction molecule 1 (STIM1) in experimental and human stroke PFLÜGERS ARCHIV 2021


  • LS4_10


  • Life-science technologies & biotechnologies

Interessi di ricerca

Renin-angiotensin-aldosterone system: systemic and tissue systems and their role in arterial hypertension.

Characterization of an animal model of arterial hypertension and target organ damage (the stroke-prone spontaneously hypertensive rat).

Molecular-genetic bases of target organ damage in hypertension (stroke, cardiac hypertrophy, renal damage) in an animal model and in humans.

Characterization of atrial natriuretic factor as a risk factor for cardiovascular diseases in the animal model and in humans.

Analysis of mitochondrial dysfunction as a molecular mechanism of hypertensive organ damage in an animal model and in humans.

Role of autophagy and mitophagy in cardiovascular diseases.



cardiovascular diseases
molecular mechanisms
animal models
natriuretic peptides
oxidative stress

Gruppi di ricerca

Laboratori di ricerca

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