Pubblicazioni

Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma

2017 - CANCER CELL

Veschi, Veronica; Liu, Zhihui; Voss, Ty C.; Ozbun, Laurent; Gryder, Berkley; Yan, Chunhua; Hu, Ying; Ma, Anqi; Jin, Jian; Mazur, Sharlyn J.; Lam, Norris; Souza, Barbara K.; Giannini, Giuseppe; Hager, Gordon L.; Arrowsmith, Cheryl H.; Khan, Javed; Appella, Ettore; Thiele, Carol J.

Discovery of a PCAF bromodomain chemical probe

2017 - ANGEWANDTE CHEMIE. INTERNATIONAL EDITION

Moustakim, Moses; Clark, Peter G. K.; Trulli, Laura; Fuentes de Arriba, Angel L.; Ehebauer, Matthias T.; Chaikuad, Apirat; Murphy, Emma J.; Mendez Johnson, Jacqui; Daniels, Danette; Hou, Chun Feng D.; Lin, Yu Hui; Walker, John R.; Hui, Raymond; Yang, Hongbing; Dorrell, Lucy; Rogers, Catherine M.; Monteiro, Octovia P.; Fedorov, Oleg; Huber, Kilian V. M.; Knapp, Stefan; Heer, Jag; Dixon, Darren J; Brennan, Paul E.

Coordinated actions of microRNAs with other epigenetic factors regulate skeletal muscle development and adaptation

2017 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bianchi, Marzia; Renzini, Alessandra; Adamo, Sergio; Moresi, Viviana

A novel epigenetic AML1-ETO/THAP10/miR-383 mini-circuitry contributes to t(8;21) leukaemogenesis

2017 - EMBO MOLECULAR MEDICINE

Li, Yonghui; Ning, Qiaoyang; Shi, Jinlong; Chen, Yang; Jiang, Mengmeng; Gao, Li; Huang, Wenrong; Jing, Yu; Huang, Sai; Liu, Anqi; Hu, Zhirui; Liu, Daihong; Wang, Lili; Nervi, Clara; Dai, Yun; Zhang, Michael Q; Yu, Li

Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy

2017 - CLINICAL EPIGENETICS

Mazzone, Roberta; Zwergel, Clemens; Mai, Antonello; Valente, Sergio

EZH2 inhibitors: a patent review (2014-2016)

2017 - EXPERT OPINION ON THERAPEUTIC PATENTS

Stazi, Giulia; Zwergel, Clemens; Mai, Antonello; Valente, Sergio

Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival

2017 - NATURE COMMUNICATIONS

Segatto, Marco; Fittipaldi, Raffaella; Pin, Fabrizio; Sartori, Roberta; Dae Ko, Kyung; Zare, Hossein; Fenizia, Claudio; Zanchettin, Gianpietro; Pierobon, Elisa Sefora; Hatakeyama, Shinji; Sperti, Cosimo; Merigliano, Stefano; Sandri, Marco; Filippakopoulos, Panagis; Costelli, Paola; Sartorelli, Vittorio; Caretti, Giuseppina

Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity

2017 - EUROPEAN HEART JOURNAL

Costantino, Sarah; Paneni, Francesco; Virdis, Agostino; Hussain, Shafaat; Mohammed, Shafeeq Ahmed; Capretti, Giuliana; Akhmedov, Alexander; Dalgaard, Kevin; Chiandotto, Sergio; Pospisilik, J Andrew; Jenuwein, Thomas; Giorgio, Marco; Volpe, Massimo; Taddei, Stefano; LÃ¼scher, Thomas F; Cosentino, Francesco

Epigenetic targets in the treatment of cancer

2017 - NOVEL APPROACHES IN DRUG DESIGNING & DEVELOPMENT

CODACCI PISANELLI, Giovanni

Alpha-lipoic acid downregulates IL-1Î² and IL-6 by DNA hypermethylation in SK-N-BE neuroblastoma cells

2017 - ANTIOXIDANTS

Dinicola, S.; Proietti, S.; Cucina, A.; Bizzarri, M.; Fuso, A.

DNA methylation profiles of selected pro-inflammatory cytokines in Alzheimer disease

2017 - JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Nicolia, V.; Cavallaro, R. A.; Lopez-Gonzalez, I.; Maccarrone, M.; Scarpa, S.; Ferrer, I.; Fuso, A.

Genome-wide identification of direct HBx genomic targets

2017 - BMC GENOMICS

Guerrieri, F.; Belloni, L.; D'Andrea, D.; Pediconi, N.; Le Pera, L.; Testoni, B.; Scisciani, C.; Floriot, O.; Zoulim, F.; Tramontano, A.; Levrero, M.

Early-life experiences and the development of adult diseases with a focus on mental illness. The Human Birth Theory

2017 - NEUROSCIENCE

Maccari, Stefania; Polese, Daniela; Reynaert, Marie Line; Amici, Tiziana; Morley Fletcher, Sara; Fagioli, Francesca

Alpha-lipoic acid represses IL-1B and IL-6 through DNA methylation in ovarian cells

2017 - PHARMANUTRITION

Dinicola, Simona; Santiago-Reyes, Myselis; Canipari, Rita; Cucina, Alessandra; Bizzarri, Mariano; Fuso, Andrea

Age-dependent increase of oxidative stress regulates microRNA-29 family preserving cardiac health

2017 - SCIENTIFIC REPORTS

Heid, Johanna; Cencioni, Chiara; Ripa, Roberto; Baumgart, Mario; Atlante, Sandra; Milano, Giuseppina; Scopece, Alessandro; Kuenne, Carsten; Guenther, Stefan; Azzimato, Valerio; Farsetti, Antonella; Rossi, Giacomo; Braun, Thomas; Pompilio, Giulio; Martelli, Fabio; M Zeiher, Andreas; Cellerino, Alessandro; Gaetano, Carlo; Spallotta, Francesco

The double life of cardiac mesenchymal cells: epimetabolic sensors and therapeutic assets for heart regeneration

2017 - PHARMACOLOGY & THERAPEUTICS

Cencioni, Chiara; Atlante, Sandra; Savoia, Matteo; Martelli, Fabio; Farsetti, Antonella; C Capogrossi, Maurizio; M Zeiher, Andreas; Gaetano, Carlo; Spallotta, Francesco

High-SETD8 inactivates p53 in neuroblastoma

2017 - ONCOSCIENCE

Veschi, Veronica; J Thiele, Carol