Pubblicazioni

Understanding retinal tau pathology through functionalÂ 2D and 3D iPSC-derived in vitroÂ retinal models

2025 - ACTA NEUROPATHOLOGICA COMMUNICATIONS

Mautone, L.; Cordella, F.; Soloperto, A.; Ghirga, S.; Di Gennaro, G.; Gigante, Y.; Di Angelantonio, S.

Ferritin nanocage-enabled detection of pathological tau in living human retinal cells

2024 - SCIENTIFIC REPORTS

Barolo, Lorenzo; Gigante, Ylenia; Mautone, Lorenza; Ghirga, Silvia; Soloperto, Alessandro; Giorgi, Alessandra; Ghirga, Francesca; Pitea, Martina; Incocciati, Alessio; Mura, Francesco; Ruocco, Giancarlo; Boffi, Alberto; Baiocco, Paola; Di Angelantonio, Silvia

HuD impairs neuromuscular junctions and induces apoptosis in human iPSC and Drosophila ALS models

2024 - NATURE COMMUNICATIONS

Silvestri, Beatrice; Mochi, Michela; Mawrie, Darilang; DE TURRIS, Valeria; Colantoni, Alessio; Borhy, Beatrice; Medici, Margherita; Nathaniel Anderson, Eric; Giovanna Garone, Maria; Patrick Zammerilla, Christopher; Simula, Marco; Ballarino, Monica; Bhan Pandey &, Udai; Rosa, Alessandro

Integrative CUT&Tag-RNA-Seq analysis of histone variant macroH2A1-dependent orchestration of human induced pluripotent stem cell reprogramming

2023 - EPIGENOMICS

Liorni, N.; Napoli, A.; Castellana, S.; Giallongo, S.; Rehakova, D.; Re, O. L.; Koutna, I.; Mazza, T.; Vinciguerra, M.

Botulinum Toxin Treatment of Adult Muscle Stem Cells from Children with Cerebral Palsy and hiPSC-Derived Neuromuscular Junctions

2023 - CELLS

Costamagna, Domiziana; Bastianini, Valeria; Corvelyn, Marlies; Duelen, Robin; Deschrevel, Jorieke; De Beukelaer, Nathalie; De Houwer, Hannah; Sampaolesi, Maurilio; Gayan-Ramirez, Ghislaine; Campenhout, Anja Van; Desloovere, Kaat

Human iPSC model reveals a central role for NOX4 and oxidative stress in Duchenne cardiomyopathy

2022 - STEM CELL REPORTS

Duelen, R.; Costamagna, D.; Gilbert, G.; Waele, L. D.; Goemans, N.; Desloovere, K.; Verfaillie, C. M.; Sipido, K. R.; Buyse, G. M.; Sampaolesi, M.

Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity

2022 - BIOMEDICINES

Scalise, Stefania; Zannino, Clara; Lucchino, Valeria; Lo Conte, Michela; Scaramuzzino, Luana; Cifelli, Pierangelo; D'Andrea, Tiziano; Martinello, Katiuscia; Fucile, Sergio; Palma, Eleonora; Gambardella, Antonio; Ruffolo, Gabriele; Cuda, Giovanni; Immacolata Parrotta, Elvira

Culture of Human iPSC-Derived Motoneurons in Compartmentalized Microfluidic Devices and Quantitative Assays for Studying Axonal Phenotypes

2022 - Methods in Molecular Biology

Garone, M. G.; D'Antoni, C.; Rosa, A.

Transport of cationic liposomes in a human blood brain barrier model: Role of the stereochemistry of the gemini amphiphile on liposome biological features

2022 - JOURNAL OF COLLOID AND INTERFACE SCIENCE

Simonis, Beatrice; Vignone, Domenico; Gonzalez Paz, Odalys; Donati, Enrica; Falchetti, Maria Laura; Bombelli, Cecilia; Cellucci, Antonella; Auciello, Giulio; Fini, Ivan; Galantini, Luciano; Syeda, Rudaba Zaman; Mazzonna, Marco; Mongiardi, Maria Patrizia; Buonocore, Francesco; Ceccacci, Francesca; Di Marco, Annalise; Mancini, Giovanna

Long-term culture of patient-derived cardiac organoids recapitulated Duchenne muscular dystrophy cardiomyopathy and disease progression

2022 - FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Marini, Vittoria; Marino, Fabiola; Aliberti, Flaminia; Giarratana, Nefele; Pozzo, Enrico; Duelen, Robin; CortÃ©s Calabuig, Ãlvaro; La Rovere, Rita; Vervliet, Tim; Torella, Daniele; Bultynck, Geert; Sampaolesi, Maurilio; Chai, Yoke Chin

Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition

2021 - STEM CELL REPORTS

Stoklund Dittlau, K.; Krasnow, E. N.; Fumagalli, L.; Vandoorne, T.; Baatsen, P.; Kerstens, A.; Giacomazzi, G.; Pavie, B.; Rossaert, E.; Beckers, J.; Sampaolesi, M.; Van Damme, P.; Van Den Bosch, L.

Generation of human motor units with functional neuromuscular junctions in microfluidic devices

2021 - JOURNAL OF VISUALIZED EXPERIMENTS

Dittlau, K. S.; Krasnow, E. N.; Fumagalli, L.; Vandoorne, T.; Baatsen, P.; Kerstens, A.; Giacomazzi, G.; Pavie, B.; Rossaert, E.; Beckers, J.; Sampaolesi, M.; Van Damme, P.; Van Den Bosch, L.

Generation and characterization of the human induced pluripotent stem cell (hiPSC) line NCUFi001-A from a patient carrying KCNQ1 G314S mutation

2021 - STEM CELL RESEARCH

Lavra, L.; Magi, F.; Ulivieri, A.; Morgante, A.; Paulis, M.; Sala, L.; Pedrazzini, M.; Polisca, P.; Rocchetti, M.; Calo, L.; Sciacchitano, S.; Salehi, L. B.

Extracellular Vesicles from Skeletal Muscle Cells Efficiently Promote Myogenesis in Induced Pluripotent Stem Cells

2020 - CELLS

Baci, D.; Chirivi, M.; Pace, V.; Maiullari, F.; Milan, M.; Rampin, A.; Somma, P.; Presutti, D.; Garavelli, S.; Bruno, A.; Cannata, S.; Lanzuolo, C.; Gargioli, C.; Rizzi, R.; Bearzi, C.

Construction of 3D in vitro models by bioprinting human pluripotent stem cells: Challenges and opportunities

2019 - BRAIN RESEARCH

Salaris, Federico; Rosa, Alessandro

Influence of substrate stiffness on human induced pluripotent stem cells: Preliminary results

2019 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

Iberite, F.; Salerno, M.; Canale, C.; Rosa, A.; Ricotti, L.

Dystrophin deficiency leads to dysfunctional glutamate clearance in iPSC derived astrocytes

2019 - TRANSLATIONAL PSYCHIATRY

Patel, A. M.; Wierda, K.; Thorrez, L.; van Putten, M.; De Smedt, J.; Ribeiro, L.; Tricot, T.; Gajjar, M.; Duelen, R.; Van Damme, P.; De Waele, L.; Goemans, N.; Tanganyika-de Winter, C.; Costamagna, D.; Aartsma-Rus, A.; van Duyvenvoorde, H.; Sampaolesi, M.; Buyse, G. M.; Verfaillie, C. M.

Direct conversion of human pluripotent stem cells into cranial motor neurons using a piggyBac vector

2018 - STEM CELL RESEARCH

De Santis, Riccardo; Garone, Maria Giovanna; Pagani, Francesca; de Turris, Valeria; Di Angelantonio, Silvia; Rosa, Alessandro

Investigation of new morpholino oligomers to increase survival motor neuron protein levels in spinal muscular atrophy

2018 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ramirez, Agnese; Crisafulli, Sebastiano G; Rizzuti, Mafalda; Bresolin, Nereo; Comi, Giacomo P; Corti, Stefania; Nizzardo, Monica

Potential of stem cell-based therapy for ischemic stroke

2018 - FRONTIERS IN NEUROLOGY

Marei, H. E.; Hasan, A.; Rizzi, R.; Althani, A.; Afifi, N.; Cenciarelli, C.; Caceci, T.; Shuaib, A.

FUS mutant human motoneurons display altered transcriptome and microRNA pathways with implications for ALS pathogenesis

2017 - STEM CELL REPORTS

DE SANTIS, Riccardo; Santini, Laura; Colantoni, Alessio; Peruzzi, Giovanna; DE TURRIS, Valeria; Alfano, Vincenzo; Bozzoni, Irene; Rosa, Alessandro

Differentiation of control and ALS mutant human iPSCs into functional skeletal muscle cells, a tool for the study of neuromuscolar diseases

2016 - STEM CELL RESEARCH

Lenzi, Jessica; Pagani, Francesca; DE SANTIS, Riccardo; Limatola, Cristina; Bozzoni, Irene; DI ANGELANTONIO, Silvia; Rosa, Alessandro

Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle

2015 - THE JOURNAL OF CLINICAL INVESTIGATION

Quattrocelli, Mattia; Swinnen, Melissa; Giacomazzi, Giorgia; Camps, Jordi; BarthÃ©lemy, Ines; Ceccarelli, Gabriele; CaluwÃ©, Ellen; Grosemans, Hanne; Thorrez, Lieven; Pelizzo, Gloria; Muijtjens, Manja; Verfaillie, Catherine M; Blot, Stephane; Janssens, Stefan; Sampaolesi, Maurilio