Pubblicazioni

Superinfections in patients treated with Teicoplanin as anti-SARS-CoV-2 agent

2021 - EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Ceccarelli, G.; Alessandri, F.; Oliva, A.; Dell'Isola, S.; Rocco, M.; Ruberto, F.; Pugliese, F.; d'Ettorre, G.; Venditti, M.

Analysis of type I IFN response and T cell activation in severe COVID-19/HIV-1 coinfection. A case report

2020 - MEDICINE

d'Ettorre, G.; Recchia, G.; Ridolfi, M.; Siccardi, G.; Pinacchio, C.; Innocenti, G. P.; Santinelli, L.; Frasca, F.; Bitossi, C.; Ceccarelli, G.; Borrazzo, C.; Antonelli, G.; Scagnolari, C.; Mastroianni, C. M.

Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis

2019 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Di Paolo, V.; Fulci, C.; Rotili, D.; Sciarretta, F.; Lucidi, A.; Morozzo della Rocca, B.; De Luca, A.; Rosato, A.; Quintieri, L.; Caccuri, A. M.

Nintedanib for systemic sclerosis-associated interstitial lung disease

2019 - NEW ENGLAND JOURNAL OF MEDICINE

Distler, O.; Highland, K. B.; Gahlemann, M.; Azuma, A.; Fischer, A.; Mayes, M. D.; Raghu, G.; Sauter, W.; Girard, M.; Alves, M.; Clerisme-Beaty, E.; Stowasser, S.; Tetzlaff, K.; Kuwana, M.; Maher, T. M.; Riccieri, V

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Talapatra, Sandeep K.; Tham, Chuin Lean; Guglielmi, Paolo; Cirilli, Roberto; Chandrasekaran, Balakumar; Karpoormath, Rajshekhar; Carradori, Simone; Kozielski, Frank

Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases

2017 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Evain Bana, Emilie; Schiavo, Lucie; Bour, Christophe; Lanfranchi, Don Antoine; Berardozzi, Simone; Ghirga, Francesca; Bagrel, Denyse; Botta, Bruno; Hanquet, Gilles; Mori, Mattia

New insights emerging from recent investigations on Human Group II pyridoxal 5'-phosphate decarboxylases

2017 - CURRENT MEDICINAL CHEMISTRY

Paiardini, Alessandro; Giardina, Giorgio; Rossignoli, Giada; Voltattorni, Carla Borri; Bertoldi, Mariarita

Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors

2016 - NUCLEIC ACIDS RESEARCH

Schneider, Anna; Corona, Angela; SpÃ£Â¶ring, Imke; Jordan, Mareike; Buchholz, Bernd; Maccioni, Elias; Di Santo, Roberto; Bodem, Jochen; Tramontano, Enzo; WÃ£Â¶hrl, Birgitta M.

Enzyme kinetics and inhibition of histone acetyltransferase KAT8

2015 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Wapenaar, Hannah; van der Wouden, Petra E; Groves, Matthew R; Rotili, Dante; Mai, Antonello; Dekker, Frank J.

A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach

2015 - JOURNAL OF MEDICINAL CHEMISTRY

Milite, Ciro; Feoli, Alessandra; Sasaki, Kazuki; La Pietra, Valeria; Balzano, Amodio Luca; Marinelli, Luciana; Mai, Antonello; Novellino, Ettore; Castellano, Sabrina; Tosco, Alessandra; Sbardella, Gianluca

A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts

2015 - ONCOTARGET

De Luca, Anastasia; ROTILI, Dante; Carpanese, Debora; Lenoci, Alessia; Calderan, Laura; Scimeca, Manuel; MAI, Antonello; Bonanno, Elena; Rosato, Antonio; Geroni, Cristina; Quintieri, Luigi; Caccuri, Anna Maria

New insights on the mechanism of quinoline-based DNA methyltransferase inhibitors

2015 - THE JOURNAL OF BIOLOGICAL CHEMISTRY

Gros, Christina; Fleury, Laurence; Nahoum, Virginie; Faux, CÃ©line; Valente, Sergio; Labella, Donatella; Cantagrel, FrÃ©dÃ©ric; Rilova, Elodie; Bouhlel, Mohamed Amine; David Cordonnier, Marie HÃ©lÃ¨ne; Dufau, Isabelle; Ausseil, FrÃ©dÃ©ric; Mai, Antonello; Mourey, Lionel; Lacroix, Laurent; Arimondo, Paola B.

Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF

2015 - CHEMMEDCHEM

Castellano, Sabrina; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Mai, Antonello; Novellino, Ettore; Tosco, Alessandra; Sbardella, Gianluca