Pubblicazioni

Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma

2024 - IMMUNITY

De Leo, Alessandra; Ugolini, Alessio; Yu, Xiaoqing; Scirocchi, Fabio; Scocozza, Delia; Peixoto, Barbara; Pace, Angelica; DâAngelo, Luca; Liu, James K. C.; Etame, Arnold B.; Rughetti, Aurelia; Nuti, Marianna; Santoro, Antonio; Vogelbaum, Michael A.; Conejo-Garcia, Jose R.; Rodriguez, Paulo C.; Veglia, Filippo

The role of glycolysis in tumorigenesis: From biological aspects to therapeutic opportunities

2024 - NEOPLASIA

Cordani, Marco; Michetti, Federica; Zarrabi, Ali; Zarepour, Atefeh; Rumio, Cristiano; Strippoli, Raffaele; Marcucci, Fabrizio

Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability

2023 - CANCERS

Caballero-Ruiz, BegoÃ±a; Gkotsi, Danai S; Ollerton, Hattie; Morales-Alcala, Cintli C; Bordone, Rosa; Jenkins, Georgia M L; Di Magno, Laura; Canettieri, Gianluca; Riobo-Del Galdo, Natalia A

Effects of Triheptanoin on Mitochondrial Respiration and Glycolysis in Cultured Fibroblasts from Neutral Lipid Storage Disease Type M (NLSD-M) Patients

2023 - BIOMOLECULES

Noguera, Nelida InÃ©s; Tavian, Daniela; Angelini, Corrado; Cortese, Francesca; Filosto, Massimiliano; Garibaldi, Matteo; Missaglia, Sara; Smigliani, Ariela; Zaza, Alessandra; Pennisi, Elena Maria

Ascorbate plus buformin in AML. A metabolic targeted treatment

2022 - CANCERS

Banella, Cristina; Catalano, Gianfranco; Travaglini, Serena; Pelosi, Elvira; Ottone, Tiziana; Zaza, Alessandra; Guerrera, Gisella; Angelini, Daniela Francesca; Niscola, Pasquale; Divona, Mariadomenica; Battistini, Luca; Screnci, Maria; Ammatuna, Emanuele; Testa, Ugo; Nervi, Clara; Voso, Maria Teresa; Noguera, Nelida Ines

Inhibition of Glycolysis Impairs Retinoic Acid-Inducible Gene I-Mediated Antiviral Responses in Primary Human Dendritic Cells

2022 - FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

Zevini, Alessandra; Palermo, Enrico; Di Carlo, Daniele; Alexandridi, Magdalini; Rinaldo, Serena; Paone, Alessio; Cutruzzola, Francesca; Etna, Marilena P; Coccia, Eliana M; Olagnier, David; Hiscott, John

Discovery of novel human lactate dehydrogenase inhibitors: Structure-based virtual screening studies and biological assessment

2022 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Di Magno, L; Coluccia, A; Bufano, M; Ripa, S; La Regina, G; Nalli, M; Di Pastena, F; Canettieri, G; Silvestri, R; Frati, L

Total metabolic tumor volume as a survival predictor for patients with diffuse large B-cell lymphoma in the GOYA study

2022 - HAEMATOLOGICA

Kostakoglu, Lale; Mattiello, Federico; Martelli, Maurizio; Sehn, Laurie H; Belada, David; Ghiggi, Chiara; Chua, Neil; GonzÃ¡lez-Barca, Eva; Hong, Xiaonan; Pinto, Antonio; Shi, Yuankai; Tatsumi, Yoichi; Bolen, Christopher; Knapp, Andrea; Sellam, Gila; Nielsen, Tina; Sahin, Deniz; Vitolo, Umberto; TrnÄnÃ½, Marek

Ascorbate plus buformin in AML: a metabolic targeted treatment

2022 - CANCERS

Normalizing hif-1Î± signaling improves cellular glucose metabolism and blocks the pathological pathways of hyperglycemic damage

2021 - BIOMEDICINES

Iacobini, C.; Vitale, M.; Pugliese, G.; Menini, S.

Disruption of redox homeostasis for combinatorial drug eefficacy in K-Ras tumors as revealed by metabolic connectivity proling

2020 - CANCER & METABOLISM

Gaglio, Daniela; Bonanomi, Marcella; Valtorta, Silvia; Bharat, Rohit; Ripamonti, Marilena; Conte, Federica; Fiscon, Giulia; Righi, Nicole; Napodano, Elisabetta; Papa, Federico; Raccagni, Isabella; Parker, Seth J.; Cifola, Ingrid; Camboni, Tania; Paci, Paola; Maria Colangelo, Anna; Vanoni, Marco; Metallo, Christian M.; Maria Moresco, Rosa; Alberghina, Lilia

Fatty acid metabolism complements glycolysis in th selective regulatory t cell expansion during tumor growth

2018 - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pacella, I; Procaccini, C; Focaccetti, C; Miacci, S; Timperi, E; Faicchia, D; Severa, M; Rizzo, F; Coccia, Em; Bonacina, F; Mitro, N; Norata, Gd; Rossetti, G; Ranzani, V; Pagani, M; Giorda, E; Wei, Y; Matarese, G; Barnaba, V; Piconese, S.

Immunometabolic profiling of T cells from patients with relapsing-remitting multiple sclerosis reveals an impairment in glycolysis and mitochondrial respiration

2017 - METABOLISM, CLINICAL AND EXPERIMENTAL

La Rocca, Claudia; Carbone, Fortunata; De Rosa, Veronica; Colamatteo, Alessandra; Galgani, Mario; Perna, Francesco; Lanzillo, Roberta; Brescia Morra, Vincenzo; Orefice, Giuseppe; Cerillo, Ilaria; Florio, Ciro; Maniscalco, Giorgia Teresa; Salvetti, Marco; Centonze, Diego; Uccelli, Antonio; Longobardi, Salvatore; Visconti, Andrea; Matarese, Giuseppe

Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3'-end processing

2016 - ELIFE

La Rosa, Piergiorgio; Bielli, Pamela; Compagnucci, Claudia; Cesari, Eleonora; Volpe, Elisabetta; Farioli Vecchioli, Stefano; Sette, Claudio

Transglutaminase 2 ablation leads to mitophagy impairment associated with a metabolic shift towards aerobic glycolysis

2015 - CELL DEATH AND DIFFERENTIATION

Rossin, F; D'Eletto, M; Falasca, L; Sepe, S; Cocco, S; FIMIA, Gian Maria; Campanella, M; Mastroberardino, P. G; Farrace, M. G; Piacentini, M.