Pubblicazioni

Cyclophosphamide alters the tumor cell secretome to potentiate the anti-myeloma activity of daratumumab through augmentation of macrophage-mediated antibody dependent cellular phagocytosis

2021 - ONCOIMMUNOLOGY

Naicker, Serika D; Feerick, Claire L; Lynch, Kevin; Swan, Dawn; Mcellistrim, Cian; Henderson, Robert; Leonard, Niamh A; Treacy, Oliver; Natoni, Alessandro; Rigalou, Athina; Cabral, Joana; Chiu, Christopher; Sasser, Kate; Ritter, Thomas; O'Dwyer, Michael; Ryan, Aideen E

Evaluating the role of FAMIly history of cancer and diagnosis of multiple neoplasms in cancer patients receiving PD-1/PD-L1 checkpoint inhibitors: the multicenter FAMI-L1 study

2020 - ONCOIMMUNOLOGY

Cortellini, A.; Buti, S.; Bersanelli, M.; Giusti, R.; Perrone, F.; Di Marino, P.; Tinari, N.; De Tursi, M.; Grassadonia, A.; Cannita, K.; Tessitore, A.; Zoratto, F.; Veltri, E.; Malorgio, F.; Russano, M.; Anesi, C.; Zeppola, T.; Filetti, M.; Marchetti, P.; Botticelli, A.; Cappellini, G. C. A.; De Galitiis, F.; Vitale, M. G.; Rastelli, F.; Pergolesi, F.; Berardi, R.; Rinaldi, S.; Tudini, M.; Silva, R. R.; Pireddu, A.; Atzori, F.; Iacono, D.; Migliorino, M. R.; Gelibter, A.; Occhipinti, M. A.; Martella, F.; Inno, A.; Gori, S.; Bracarda, S.; Zannori, C.; Mosillo, C.; Parisi, A.; Porzio, G.; Mallardo, D.; Fargnoli, M. C.; Tiseo, M.; Santini, D.; Ascierto, P. A.; Ficorella, C.

Evaluating the role of FAMIly history of cancer and diagnosis of multiple neoplasms in cancer patients receiving PD-1/PD-L1 checkpoint inhibitors. the multicenter FAMI-L1 study

2020 - ONCOIMMUNOLOGY

Cortellini, A.; Buti, S.; Bersanelli, M.; Giusti, R.; Perrone, F.; Di Marino, P.; Tinari, N.; De Tursi, M.; Grassadonia, A.; Cannita, K.; Tessitore, A.; Zoratto, F.; Veltri, E.; Malorgio, F.; Russano, M.; Anesi, C.; Zeppola, T.; Filetti, M.; Marchetti, P.; Botticelli, A.; Cappellini, G. C. A.; De Galitiis, F.; Vitale, M. G.; Rastelli, F.; Pergolesi, F.; Berardi, R.; Rinaldi, S.; Tudini, M.; Silva, R. R.; Pireddu, A.; Atzori, F.; Iacono, D.; Migliorino, M. R.; Gelibter, A.; Occhipinti, M.; Martella, F.; Inno, A.; Gori, S.; Bracarda, S.; Zannori, C.; Mosillo, C.; Parisi, A.; Porzio, G.; Mallardo, D.; Fargnoli, M. C.; Tiseo, M.; Santini, D.; Ascierto, P. A.; Ficorella, C.

Tailoring CD19xCD3-DART exposure enhances T-cells to eradication of B-cell neoplasms.

2018 - ONCOIMMUNOLOGY

Circosta, P; Elia, Ar; Landra, I; Machiorlatti, R; Todaro, M; Aliberti, S; Brusa, D; Deaglio, S; Chiaretti, S; Bruna, R; Gottardi, D; Massaia, M; Giacomo, Fd; Guarini, Ar; FoÃ , R; Kyriakides, Pw; Bareja, R; Elemento, O; Chichili, Gr; Monteleone, E; Moore, Pa; Johnson, S; Bonvini, E; Cignetti, A; Inghirami, G.

Choice of costimulatory domains and of cytokines determines CAR T-cell activity in neuroblastoma

2018 - ONCOIMMUNOLOGY

Quintarelli, Concetta; Orlando, Domenico; Boffa, Iolanda; Guercio, Marika; Polito, Vinicia Assunta; Petretto, Andrea; Lavarello, Chiara; Sinibaldi, Matilde; Weber, Gerrit; Del Bufalo, Francesca; Giorda, Ezio; Scarsella, Marco; Petrini, Stefania; Pagliara, Daria; Locatelli, Franco; De Angelis, Biagio; Caruana, Ignazio

Bevacizumab-mediated tumor vasculature remodelling improves tumor infiltration and antitumor efficacy of gd2-car t cells in a human neuroblastoma preclinical model

2018 - ONCOIMMUNOLOGY

Bocca, P.; Di Carlo, E.; Caruana, I.; Emionite, L.; Cilli, M.; De Angelis, B.; Quintarelli, C.; Pezzolo, A.; Raffaghello, L.; Morandi, F.; Locatelli, F.; Pistoia, V.; Prigione, I.

A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets

2018 - ONCOIMMUNOLOGY

F Almeida, Francisca; Tognarelli, Sara; MarÃ§ais, Antoine; J Kueh, Andrew; E Friede, Miriam; Liao, Yang; N Willis, Simon; Luong, Kylie; Faure, Fabrice; E Mercier, Francois; Galluso, Justine; Firth, Matthew; Narni-Mancinelli, Emilie; Rais, Bushra; T Scadden, David; Spallotta, Francesco; Weil, Sandra; Giannattasio, Ariane; Kalensee, Franziska; ZÃ¶ller, Tobias; D Huntington, Nicholas; Schleicher, Ulrike; G Chiocchetti, Andreas; Ugolini, Sophie; J Herold, Marco; Shi, Wei; Koch, Joachim; Steinle, Alexander; Vivier, Eric; Walzer, Thierry; T Belz, Gabrielle; Ullrich, Evelyn

Eosinophils: The unsung heroes in cancer?

2018 - ONCOIMMUNOLOGY

Varricchi, Gilda; Galdiero, Maria Rosaria; Loffredo, Stefania; Lucarini, Valeria; Marone, Giancarlo; Mattei, Fabrizio; Marone, Gianni; Schiavoni, Giovanna

p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells

2017 - ONCOIMMUNOLOGY

Soriani, Alessandra; Borrelli, Cristiana; Ricci, Biancamaria; Molfetta, Rosa; Zingoni, Alessandra; Fionda, Cinzia; Carnevale, Silvia; Abruzzese, MARIA PIA; Petrucci, MARIA TERESA; Ricciardi, Maria Rosaria; LA REGINA, Giuseppe; Cesare, Erica Di; Lavia, Patrizia; Silvestri, Romano; Paolini, Rossella; Cippitelli, Marco; Santoni, Angela

Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: role of HSP70/TLR2/NF-kB axis

2017 - ONCOIMMUNOLOGY

Vulpis, Elisabetta; Cecere, Francesca; Molfetta, Rosa; Soriani, Alessandra; Fionda, Cinzia; Peruzzi, Giovanna; Caracciolo, Giulio; Palchetti, Sara; Masuelli, Laura; Simonelli, Lucilla; D'Oro, Ugo; Abruzzese, MARIA PIA; Petrucci, MARIA TERESA; Ricciardi, Maria Rosaria; Paolini, Rossella; Cippitelli, Marco; Santoni, Angela; Zingoni, Alessandra

Obinutuzumab-mediated high-affinity ligation of FcÎ³RIIIA/CD16 primes NK cells for IFNÎ³ production

2017 - ONCOIMMUNOLOGY

Capuano, Cristina; Pighi, Chiara; Molfetta, Rosa; Paolini, Rossella; Battella, Simone; Palmieri, Gabriella; Giannini, Giuseppe; Belardinilli, Francesca; Santoni, Angela; Galandrini, Ricciarda

Reconstitution of multifunctional CD56(low)CD16(low) natural killer cell subset in children with acute leukemia given Î±/Î² T cell-depleted HLA-haploidentical haematopoietic stem cell transplantation

2017 - ONCOIMMUNOLOGY

Stabile, MARIA HELENA; Nisti, Paolo; Peruzzi, Giovanna; Fionda, Cinzia; Daria, Pagliara; Letizia, Pomonia Brescia; Pietro, Merli; Locatelli, Franco; Santoni, Angela; Gismondi, Angela

Chloroquine supplementation increases the cytotoxic effect of curcumin against Her2/neu overexpressing breast cancer cells in vitro and in vivo in nude mice while counteracts it in immune competent mice

2017 - ONCOIMMUNOLOGY

Masuelli, L.; Granato, M.; Benvenuto, M.; Mattera, R.; Bernardini, R.; Mattei, M.; d'Amati, G.; D'Orazi, Giulio; Faggioni, A.; Bei, R.; Cirone, M.

PD-L1 and epithelial-mesenchymal transition in circulating tumor cells from non-small cell lung cancer patients: a molecular shield to evade immune system?

2017 - ONCOIMMUNOLOGY

Raimondi, Cristina; Carpino, Guido; Nicolazzo, Chiara; Gradilone, Angela; Gianni, Walter; Gelibter, Alain; Gaudio, Eugenio; Cortesi, Enrico; Gazzaniga, Paola

IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils

2017 - ONCOIMMUNOLOGY

Lucarini, V.; Ziccheddu, G.; Macchia, I.; La Sorsa, V.; Peschiaroli, F.; Buccione, C.; Sistigu, A.; Sanchez, M.; Andreone, S.; D'Urso, M. T.; Spada, M.; Macchia, D.; Afferni, C.; Mattei, F.; Schiavoni, G.

MYCN is an immunosuppressive oncogene dampening the expression of ligands for NK-cell-activating receptors in human high-risk neuroblastoma

2017 - ONCOIMMUNOLOGY

Brandetti, E.; Veneziani, I.; Melaiu, O.; Pezzolo, A.; Castellano, A.; Boldrini, R.; Ferretti, E.; Fruci, D.; Moretta, L.; Pistoia, V.; Locatelli, F.; Cifaldi, L.

Zoledronic acid boosts Î³Î´ T-cell activity in children receiving Î±Î²+ T and CD19+ cell-depleted grafts from an HLA-haplo-identical donor

2017 - ONCOIMMUNOLOGY

Bertaina, A.; Zorzoli, A.; Petretto, A.; Barbarito, G.; Inglese, E.; Merli, P.; Lavarello, C.; Brescia, L. P.; De Angelis, B.; Tripodi, G.; Moretta, L.; Locatelli, F.; Airoldi, I.

IL-18 receptor marks functional CD8 T cells in non-small cell lung cancer

2017 - ONCOIMMUNOLOGY

Timperi, Eleonora; Focaccetti, Chiara; Gallerano, Daniela; Panetta, Mariangela; Spada, Sheila; Gallo, Enzo; Visca, Paolo; Venuta, Federico; Diso, Daniele; Prelaj, Arsela; Longo, Flavia; Facciolo, Francesco; NisticÃ², Paola; Barnaba, Vincenzo

Type-I-interferons in infection and cancer: Unanticipated dynamics with therapeutic implications

2017 - ONCOIMMUNOLOGY

Musella, Martina; Manic, Gwenola; De Maria, Ruggero; Vitale, Ilio; Sistigu, Antonella

Polyfunctional Melan-A-specific tumor-reactive CD8+ T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS

2016 - ONCOIMMUNOLOGY

Ornella, Franzesea; Belinda, Palermobc; Cosmo Di, Donnac; Isabella, Sperdutid; Virginia, Ferraresie; Stabile, MARIA HELENA; Gismondi, Angela; Santoni, Angela

Role of natural killer cell subsets and natural cytotoxicity receptors for the outcome of immunotherapy in acute myeloid leukemia

2016 - ONCOIMMUNOLOGY

Martner, Anna; RydstrÃ¶m, Anna; Riise, Rebecca E.; Aurelius, Johan; Anderson, Harald; Brune, Mats; Foa, Roberto; Hellstrand, Kristoffer; ThorÃ©n, Fredrik B.

Regulatory T cells with multiple suppressive and potentially pro-tumor activities accumulate in human colorectal cancer

2016 - ONCOIMMUNOLOGY

Timperi, Eleonora; Pacella, Ilenia; Schinzari, Valeria; Focaccetti, Chiara; Sacco, Luca; Farelli, Francesco; Caronna, Roberto; Del Bene, Gabriella; Longo, Flavia; Ciardi, Antonio; Morelli, Sergio; Vestri, Anna Rita; Chirletti, Piero; Barnaba, Vincenzo; Piconese, Silvia

Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cells

2016 - ONCOIMMUNOLOGY

Antonangeli, Fabrizio; Soriani, Alessandra; Ricci, B; Ponzetta, A; Benigni, G; Morrone, Stefania; Bernardini, Giovanni; Santoni, Angela

PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance

2016 - ONCOIMMUNOLOGY

Dondero, A.; Pastorino, F.; Della Chiesa, M.; Corrias, M. V.; Morandi, F.; Pistoia, V.; Olive, D.; Bellora, F.; Locatelli, F.; Castellano, A.; Moretta, L.; Moretta, A.; Bottino, C.; Castriconi, R.

Zoledronic acid boosts Î³Î´ t-cell activity in children receiving Î±Î²+ t and cd19+ cell-depleted grafts from an hla-haplo-identical donor

2016 - ONCOIMMUNOLOGY

Bertaina, A.; Zorzoli, A.; Petretto, A.; Barbarito, G.; Inglese, E.; Merli, P.; Lavarello, C.; Brescia, L. P.; De Angelis, B.; Tripodi, G.; Moretta, L.; Locatelli, F.; Airoldi, I.