Pubblicazioni

Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Saccoliti, Francesco; Madia, VALENTINA NOEMI; Tudino, Valeria; DE LEO, Alessandro; Pescatori, Luca; Messore, Antonella; DE VITA, Daniela; Scipione, Luigi; Brun, Reto; Kaiser, Marcel; MÃ¤ser, Pascal; Magalhaes Calvet, Claudia; K Jennings, Gareth; M Podust, Larissa; Costi, Roberta; DI SANTO, Roberto

pH-sensitive niosomes: effects on cytotoxicity and on inflammation and pain in murine models

2017 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Rinaldi, Federica; Del Favero, Elena; Rondelli, Valeria; Pieretti, Stefano; Bogni, Alessia; Ponti, Jessica; Rossi, FranÃ§ois; Di Marzio, Luisa; Paolino, Donatella; Marianecci, Carlotta; Carafa, Maria

Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases

2017 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Evain Bana, Emilie; Schiavo, Lucie; Bour, Christophe; Lanfranchi, Don Antoine; Berardozzi, Simone; Ghirga, Francesca; Bagrel, Denyse; Botta, Bruno; Hanquet, Gilles; Mori, Mattia

Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: evaluation of antimicrobial, cytotoxic and hemolytic activities

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Merlino, Francesco; Carotenuto, Alfonso; Casciaro, Bruno; Martora, Francesca; Loffredo, MARIA ROSA; DI GRAZIA, Antonio; Yousif, Ali M.; Brancaccio, Diego; Palomba, Luciana; Novellino, Ettore; Galdiero, Massimiliano; Iovene, Maria Rosaria; Mangoni, Maria Luisa; Grieco, Paolo

Defective DNA repair mechanisms in prostate cancer: impact of olaparib

2017 - DRUG DESIGN, DEVELOPMENT AND THERAPY

De Felice, Francesca; Tombolini, Vincenzo; Marampon, Francesco; Musella, Angela; Marchetti, Claudia

Effects of curcumin and curcumin analogues on TRP channels

2017 - FITOTERAPIA

Nalli, Marianna; Ortar, Giorgio; Schiano Moriello, Aniello; Di Marzo, Vincenzo; De Petrocellis, Luciano

Targeting endothelin-1 receptor/ÃÂ²-arrestin1 network for the treatment of ovarian cancer

2017 - EXPERT OPINION ON THERAPEUTIC TARGETS

RosanÃ£Â², Laura; Cianfrocca, Roberta; Sestito, Rosanna; Tocci, Piera; Di Castro, Valeriana; Bagnato, Anna

Virtual screening for the development of dual-inhibitors targeting topoisomerase IB and tyrosyl-DNA phosphodiesterase 1

2017 - CURRENT DRUG TARGETS

Cardamone, Francesca; Pizzi, Simone; Iacovelli, Federico; Falconi, Mattia; Desideri, Alessandro

Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the Î±3Î²4 nicotinic acetylcholine receptor subtype

2016 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Matera, Carlo; Quadri, Marta; Sciaccaluga, Miriam; PomÃ¨, Diego Yuri; Fasoli, Francesca; De Amici, Marco; Fucile, Sergio; Gotti, Cecilia; Dallanoce, Clelia; Grazioso, Giovanni

Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions

2016 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Drinkwater, Nyssa; Vinh, Natalie B.; Mistry, Shailesh N.; Bamert, Rebecca S.; Ruggeri, Chiara; Holleran, John P.; Loganathan, Sasdekumar; Paiardini, Alessandro; Charman, Susan A.; Powell, Andrew K.; Avery, Vicky M.; Mcgowan, Sheena; Scammells, Peter J.

Vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors: development and validation of predictive 3-D QSAR models through extensive ligand- and structure-based approaches

2015 - JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Ragno, Rino; Ballante, Flavio; Pirolli, Adele; Wickersham, Richard B; Patsilinakos, Alexandros; Hesse, StÃ©phanie; Perspicace, Enrico; Kirsch, Gilbert

Emerging approaches for histone deacetylase inhibitor drug discovery

2015 - EXPERT OPINION ON DRUG DISCOVERY

Zwergel, Clemens; Valente, Sergio; Jacob, Claus; Mai, Antonello

Differential effects of extracellular vesicles secreted by mesenchymal stem cells from different sources on glioblastoma cells

2015 - EXPERT OPINION ON BIOLOGICAL THERAPY

Del Fattore, Andrea; Luciano, Rosa; Saracino, Rossana; Battafarano, Giulia; Rizzo, Cristiano; Pascucci, Luisa; Alessandri, Giulio; Pessina, Augusto; Perrotta, Antonio; Fierabracci, Alessandra; Muraca, Maurizio

A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach

2015 - JOURNAL OF MEDICINAL CHEMISTRY

Milite, Ciro; Feoli, Alessandra; Sasaki, Kazuki; La Pietra, Valeria; Balzano, Amodio Luca; Marinelli, Luciana; Mai, Antonello; Novellino, Ettore; Castellano, Sabrina; Tosco, Alessandra; Sbardella, Gianluca

Chemistry and pharmacology of a series of unichiral analogues of 2-(2-pyrrolidinyl)-1,4-benzodioxane, prolinol phenyl ether, and prolinol 3-pyridyl ether designed as Î±4Î²2-nicotinic acetylcholine receptor agonists

2015 - JOURNAL OF MEDICINAL CHEMISTRY

Bolchi, Cristiano; Valoti, Ermanno; Gotti, Cecilia; Fasoli, Francesca; Ruggeri, Paola; Fumagalli, Laura; Binda, Matteo; Mucchietto, Vanessa; Sciaccaluga, Miriam; Budriesi, Roberta; Fucile, Sergio; Pallavicini, Marco

Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors

2015 - BIOORGANIC & MEDICINAL CHEMISTRY

Consalvi, Sara; Alfonso, Salvatore; Di Capua, Angela; Poce, Giovanna; Pirolli, Adele; Sabatino, Manuela; Ragno, Rino; Anzini, Maurizio; Sartini, Stefania; La Motta, Concettina; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Biava, Mariangela