Pubblicazioni

Evaluation of the cellular protection by novel spiropyrazole compounds in dopaminergic cell death

2021 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Zaiter, Jamila; Hibot, Achraf; Hafid, Abderrafia; Khouili, Mostafa; Neves, Claudia M. B.; SimÃµes, MÃ¡rio M. Q.; Neves, M. GraÃ§a P. M. S.; Faustino, M. Amparo F.; Dagci, Taner; Saso, Luciano; Armagan, GÃ¼liz

Naturally occurring diels-alder-type adducts from morus nigra as potent inhibitors of mycobacterium tuberculosis protein tyrosine phosphatase B

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Mascarello, Alessandra; Orbem Menegatti, Angela Camila; Calcaterra, Andrea; Martins, Priscila Graziela Alves; Chiaradia-Delatorre, Louise Domeneghini; D'Acquarica, Ilaria; Ferrari, Franco; Pau, Valentina; Sanna, Adriana; De Logu, Alessandro; Botta, Maurizio; Botta, Bruno; Terenzi, HernÃ£Â¡n; Mori, Mattia

In vivo potent BM635 analogue with improved drug-like properties

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Poce, Giovanna; Cocozza, Martina; Alfonso, Salvatore; Consalvi, Sara; Venditti, Giulia; Fernandez-Menendez, Raquel; Bates, Robert H.; Barros Aguirre, David; Ballell, Lluis; De Logu, Alessandro; Vistoli, Giulio; Biava, Mariangela

Efficient synthesis and first regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold and their evaluation in H2O2-induced oxidative stress

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Loubidi, Mohammed; Jouha, Jabrane; Tber, Zahira; Khouili, Mostafa; Suzenet, Franck; Akssira, Mohamed; Erdogan, MÃ¼min Alper; KÃ¶se, Fadime AydÄ±n; DagcÄ±, Taner; Armagan, GÃ¼liz; Saso, Luciano; Guillaumet, GÃ©rald

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Talapatra, Sandeep K.; Tham, Chuin Lean; Guglielmi, Paolo; Cirilli, Roberto; Chandrasekaran, Balakumar; Karpoormath, Rajshekhar; Carradori, Simone; Kozielski, Frank

From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at Î±4Î²2 nicotinic acetylcholine receptor

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Bolchi, Cristiano; Bavo, Francesco; Gotti, Cecilia; Fumagalli, Laura; Fasoli, Francesca; Binda, Matteo; Mucchietto, Vanessa; Sciaccaluga, Miriam; Plutino, Simona; Fucile, Sergio; Pallavicini, Marco

Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Zwergel, Clemens; Czepukojc, Brigitte; Evain Bana, Emilie; Xu, Zhanjie; Stazi, Giulia; Mori, Mattia; Patsilinakos, Alexandros; Mai, Antonello; Botta, Bruno; Ragno, Rino; Bagrel, Denise; Kirsch, Gilbert; Meiser, Peter; Jacob, Claus; Montenarh, Mathias; Valente, Sergio

Enhancing activity and selectivity in a series of pyrrol-1-yl-1-hydroxypyrazole-based aldose reductase inhibitors: the case of trifluoroacetylation

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Papastavrou, Nikolaos; Chatzopoulou, Maria; Ballekova, Jana; Cappiello, Mario; Moschini, Roberta; Balestri, Francesco; Patsilinakos, Alexandros; Ragno, Rino; Stefek, Milan; Nicolaou, Ioannis

Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: evaluation of antimicrobial, cytotoxic and hemolytic activities

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Merlino, Francesco; Carotenuto, Alfonso; Casciaro, Bruno; Martora, Francesca; Loffredo, MARIA ROSA; DI GRAZIA, Antonio; Yousif, Ali M.; Brancaccio, Diego; Palomba, Luciana; Novellino, Ettore; Galdiero, Massimiliano; Iovene, Maria Rosaria; Mangoni, Maria Luisa; Grieco, Paolo

In vitro screening of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives as antiprotozoal agents and docking studies on Trypanosoma cruzi CYP51

2016 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

DE VITA, Daniela; Moraca, Francesca; Zamperini, Claudio; Pandolfi, Fabiana; DI SANTO, Roberto; Matheeussen, An; Maes, Louis; Tortorella, Silvano; Scipione, Luigi

Discovery of N-aryl-naphthylamines as in vitro inhibitors of the interaction between HIV integrase and the cofactor LEDGF/p75

2015 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cuzzucoli Crucitti, G.; Pescatori, Luca; Messore, A. A; Madia, VALENTINA NOEMI; Pupo, Giovanni; Saccoliti, Francesco; Scipione, Luigi; Tortorella, Silvano; Di Leva, F. S; Cosconati, S; Novellino, E; Debyser, Z; Christ, F; Costi, Roberta; DI SANTO, Roberto