Pubblicazioni

Abstract PR010: Linking proliferation rate to the evolution of single-cell primary and metastatic tumor clones

2024 - CANCER RESEARCH

Lucas, Olivia; Ward, Sophia; Zaidi, Rija; Bunkum, Abigail; Frankell, Alexander M.; Moore, David A.; Hill, Mark S.; Liu, Wing Kin; Marinelli, Daniele; Lim, Emilia L.; Hessey, Sonya; Naceur-Lombardelli, Cristina; Rowan, Andrew; Mann, Sukhveer; Zhai, Haoran; Dietzen, Michelle; Ding, Boyue; Royle, Gary; Mcgranahan, Nicholas; Jamal-Hanjani, Mariam; Kanu, Nnennaya; Swanton, Charles; Zaccaria, Simone

Circulating immature neutrophils early detect hyperprogressive disease upon first-line PD-1/PD-L1 inhibitors in non-small cell lung cancer patients selecting best candidates for platinum-based chemotherapy and PD-1/PD-L1 inhibitors combinations

2023 - CANCER RESEARCH

Ferrara, R; Lo Russo, G; Ciniselli, Cm; Piva, A; Bassani, B; Jachetti, E; Calareso, G; Duroni, V; Di Gregorio, S; Proto, C; Prelaj, A; De Toma, A; Occhipinti, M; Brambilla, M; Manglaviti, S; Mazzeo, L; Rinaldi, A; Beninato, T; Ganzinelli, M; De Braud, F; Garassino, Mc; Verderio, P; Colombo, Mp; Sangaletti, S

Targeting chemotherapy to decondensed H3K27me3-marked chromatin of AML Cells enhances Leukemia suppression

2022 - CANCER RESEARCH

Porazzi, P.; Petruk, S.; Pagliaroli, L.; De Dominici, M.; Deming, D.; Puccetti, M. V.; Kushinsky, S.; Kumar, G.; Minieri, V.; Barbieri, E.; Deliard, S.; Grande, A.; Trizzino, M.; Gardini, A.; Canaani, E.; Palmisiano, N.; Porcu, P.; Ertel, A.; Fortina, P.; Eischen, C. M.; Mazo, A.; Calabretta, B.

Abstract 2380: The effect of metabolic alterations on chemo-immunotherapy response in non-small-cell lung cancer model

2022 - CANCER RESEARCH

Ndembe, Gloriana; Marabese, Mirko; Intini, Ilenia; Fabbri, Alessandra; Moro, Massimo; Occhipinti, Mario; Sottotetti, Elisa; Russo, Giuseppe Lo; Ganzinelli, Monica; Broggini, Massimo

Lipid-associated macrophages are induced by cancer-associated fibroblasts and mediate immune suppression in breast cancer

2022 - CANCER RESEARCH

Timperi, Eleonora; Gueguen, Paul; Molgora, Martina; Magagna, Ilaria; Kieffer, Yann; Lopez-Lastra, Silvia; Sirven, Philemon; Baudrin, Laura G; Baulande, Sylvain; Nicolas, Andre; Champenois, Gabriel; Meseure, Dider; Vincent-Salomon, Anne; Tardivon, Anne; Laas, Enora; Soumelis, Vassili; Colonna, Marco; Mechta-Grigoriou, Fatima; Amigorena, Sebastian; Romano, Emanuela

Abstract 6307: The botanical drug PBI-05204, a supercritical CO2 extract of Nerium oleander, augments the antitumor efficacy of radiotherapy in treatment of human glioblastoma

2022 - CANCER RESEARCH

Colapietro, Alessandro; Yang, Peiying; Rosetti, Alessandra; Mancini, Andrea; Vital, Flora; Martellucci, Stefano; Marampon, Francesco; Mattei, Vincenzo; Luca Gravina, Giovanni; Newman, Robert; Festuccia, Claudio

Pan-Cancer Analysis of Canonical and Modified miRNAs Enhances the Resolution of the Functional miRNAome in Cancer

2022 - CANCER RESEARCH

Distefano, Rosario; Tomasello, Luisa; Rampioni Vinciguerra, Gian Luca; Gasparini, Pierluigi; Xiang, Yujia; Bagnoli, Marina; Marceca, Gioacchino P; Fadda, Paolo; LaganÃ , Alessandro; Acunzo, Mario; Ma, Qin; Nigita, Giovanni; Croce, Carlo M

Immunometabolism of circulating neutrophils in hyperprogressive disease (HPD) upon first-line PD-1/PD-L1 inhibitors (ICI) alone or in combination with platinum-based chemotherapy (PCT) in non-small cell lung cancer (NSCLC) patients (pts)

2021 - CANCER RESEARCH

Ferrara, R; Jachetti, E; Calareso, G; Brambilla, M; Lo Russo, G; Proto, C; Prelaj, A; Signorelli, D; Galli, G; De Toma, A; Occhipinti, M; Manglaviti, S; Labianca, A; Ganzinelli, M; Spano, Sm; Molino, G; Martinetti, A; Greco, Fg; Bini, M; Beninato, T; de Braud, F; Colombo, Mp; Garassino, Mc; Sangaletti, S

Downregulation of miR-223 expression is an early event during mammary transformation and confers resistance to CDK4/6 inhibitors in luminal breast cancer

2020 - CANCER RESEARCH

Citron, F.; Segatto, I.; Vinciguerra, G. L. R.; Musco, L.; Russo, F.; Mungo, G.; D'Andrea, S.; Mattevi, M. C.; Perin, T.; Schiappacassi, M.; Massarut, S.; Marchini, C.; Amici, A.; Vecchione, A.; Baldassarre, G.; Belletti, B.

Matched germline and tumor profiling in male breast cancer for the discovery of molecular subtypes with clinical relevance

2020 - CANCER RESEARCHCancer Research

Zelli, V; Silvestri, V; Valentini, V; Bucalo, A; Rizzolo, P; Zanna, I; Cortesi, L; Calistri, D; Tibiletti, Mg; Giannini, G; Fox, Sb; Palli, D; Ottini, L

Design and functional validation of a mutant variant of the lncRNA HOTAIR to counteract Snail function in Epithelial-to-Mesenchymal Transition

2020 - CANCER RESEARCH

Battistelli, Cecilia; Garbo, Sabrina; Riccioni, Veronica; Montaldo, Claudia; Santangelo, Laura; Vandelli, Andrea; Strippoli, Raffaele; Tartaglia, Gian Gaetano; Tripodi, Marco; Cicchini, Carla

Transcription factors involved in tumorigenesis are over-represented in mutated active DNA-binding sites in neuroblastoma A C

2020 - CANCER RESEARCH

Capasso, M.; Lasorsa, V. A.; Cimmino, F.; Avitabile, M.; Cantalupo, S.; Montella, A.; De Angelis, B.; Morini, M.; De Torres, C.; Castellano, A.; Locatelli, F.; Iolascon, A.

Transcription factors involved in tumorigenesis are over-represented in mutated active DNA-binding sites in neuroblastoma A C

2020 - CANCER RESEARCH

Capasso, M.; Lasorsa, V. A.; Cimmino, F.; Avitabile, M.; Cantalupo, S.; Montella, A.; De Angelis, B.; Morini, M.; De Torres, C.; Castellano, A.; Locatelli, F.; Iolascon, A.

Stathmin is required for normal mouse mammary gland development and D16Her2-driven tumorigenesis

2019 - CANCER RESEARCH

Segatto, I.; De Marco Zompit, M.; Citron, F.; D'Andrea, S.; Vinciguerra, G. L. R.; Perin, T.; Berton, S.; Mungo, G.; Schiappacassi, M.; Marchini, C.; Amici, A.; Vecchione, A.; Baldassarre, G.; Belletti, B.

Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains CRC progression and chemoresistance

2019 - CANCER RESEARCH

Pelullo, Maria; Nardozza, Francesca; Zema, Sabrina; Quaranta, Roberta; Nicoletti, Carmine; Besharat, ZEIN MERSINI; Felli, MARIA PIA; Cerbelli, Bruna; DâAmati, Giulia; Palermo, Rocco; Capalbo, Carlo; Talora, Claudio; DI MARCOTULLIO, Lucia; Giannini, Giuseppe; Checquolo, Saula; Screpanti, Isabella; Bellavia, Diana

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

2019 - CANCER RESEARCH

Patel, Vivek L; Busch, Evan L; Friebel, Tara M; Cronin, Angel; Leslie, Goska; Mcguffog, Lesley; Adlard, Julian; Agata, Simona; Agnarsson, Bjarni A; Ahmed, Munaza; AittomÃ¤ki, Kristiina; Alducci, Elisa; Andrulis, Irene L; Arason, Adalgeir; Arnold, Norbert; Artioli, Grazia; Arver, Brita; Auber, Bernd; Azzollini, Jacopo; BalmaÃ±a, Judith; Barkardottir, Rosa B; Barnes, Daniel R; Barroso, Alicia; Barrowdale, Daniel; Belotti, Muriel; Benitez, Javier; Bertelsen, Brigitte; Blok, Marinus J; Bodrogi, Istvan; Bonadona, ValÃ©rie; Bonanni, Bernardo; Bondavalli, Davide; Boonen, Susanne E; Borde, Julika; Borg, Ake; Bradbury, Angela R; Brady, Angela; Brewer, Carole; Brunet, Joan; Buecher, Bruno; Buys, Saundra S; Cabezas-Camarero, Santiago; CaldÃ©s, Trinidad; Caliebe, Almuth; Caligo, Maria A; Calvello, Mariarosaria; Campbell, Ian G; Carnevali, Ileana; Carrasco, Estela; Chan, Tsun L; Chu, Annie T W; Chung, Wendy K; Claes, Kathleen B M; Collaborators, Gemo Study; Collaborators, Embrace; Cook, Jackie; Cortesi, Laura; Couch, Fergus J; Daly, Mary B; Damante, Giuseppe; Darder, Esther; Davidson, Rosemarie; de la Hoya, Miguel; Della Puppa, Lara; Dennis, Joe; DÃez, Orland; Ding, Yuan Chun; Ditsch, Nina; Domchek, Susan M; Donaldson, Alan; Dworniczak, Bernd; Easton, Douglas F; Eccles, Diana M; Eeles, Rosalind A; Ehrencrona, Hans; Ejlertsen, Bent; Engel, Christoph; Evans, D Gareth; Faivre, Laurence; Faust, Ulrike; FeliubadalÃ³, LÃdia; Foretova, Lenka; Fostira, Florentia; Fountzilas, George; Frost, Debra; GarcÃa-BarberÃ¡n, Vanesa; Garre, Pilar; Gauthier-Villars, Marion; GÃ©czi, Lajos; Gehrig, Andrea; Gerdes, Anne-Marie; Gesta, Paul; Giannini, Giuseppe; Glendon, Gord; Godwin, Andrew K; Goldgar, David E; Greene, Mark H; Gutierrez-Barrera, Angelica M; Hahnen, Eric; Hamann, Ute; Hauke, Jan; Herold, Natalie; Hogervorst, Frans B L; Honisch, Ellen; Hopper, John L; Hulick, Peter J; Investigators, Kconfab; Investigators, Hebon; Izatt, Louise; Jager, Agnes; James, Paul; Janavicius, Ramunas; Jensen, Uffe Birk; Jensen, Thomas Dyrso; Johannsson, Oskar Th; John, Esther M; Joseph, Vijai; Kang, Eunyoung; Kast, Karin; Kiiski, Johanna I; Kim, Sung-Won; Kim, Zisun; Ko, Kwang-Pil; Konstantopoulou, Irene; Kramer, Gero; Krogh, Lotte; Kruse, Torben A; Kwong, Ava; Larsen, Mirjam; Lasset, Christine; Lautrup, Charlotte; LÃ¡zaro, Conxi; Lee, Jihyoun; Lee, Jong Won; Lee, Min Hyuk; Lemke, Johannes; Lesueur, Fabienne; Liljegren, Annelie; Lindblom, Annika; Llovet, Patricia; Lopez-FernÃ¡ndez, Adria; Lopez-Perolio, Irene; Lorca, Victor; Loud, Jennifer T; Ma, Edmond S K; Mai, Phuong L; Manoukian, Siranoush; Mari, Veronique; Martin, Lynn; Matricardi, Laura; Mebirouk, Noura; Medici, Veronica; Meijers-Heijboer, Hanne E J; Meindl, Alfons; Mensenkamp, Arjen R; Miller, Clare; Molina Gomes, Denise; Montagna, Marco; Mooij, Thea M; Moserle, Lidia; Mouret-Fourme, Emmanuelle; Mulligan, Anna Marie; Nathanson, Katherine L; Navratilova, Marie; Nevanlinna, Heli; Niederacher, Dieter; Cilius Nielsen, Finn C; Nikitina-Zake, Liene; Offit, Kenneth; Olah, Edith; Olopade, Olufunmilayo I; Ong, Kai-Ren; Osorio, Ana; Ott, Claus-Eric; Palli, Domenico; Park, Sue K; Parsons, Michael T; Pedersen, Inge Sokilde; Peissel, Bernard; Peixoto, Ana; PÃ©rez-Segura, Pedro; Peterlongo, Paolo; HÃ¸gh Petersen, Annabeth; Porteous, Mary E; Pujana, Miguel Angel; Radice, Paolo; Ramser, Juliane; Rantala, Johanna; Rashid, Muhammad U; Rhiem, Kerstin; Rizzolo, Piera; Robson, Mark E; Rookus, Matti A; Rossing, Caroline Maria; Ruddy, Kathryn J; Santos, Catarina; Saule, Claire; Scarpitta, Rosa; Schmutzler, Rita K; Schuster, HÃ©lÃ¨ne; Senter, Leigha; Seynaeve, Caroline M; Shah, Payal D; Sharma, Priyanka; Shin, Vivian Y; Silvestri, Valentina; Simard, Jacques; Singer, Christian F; Skytte, Anne-Bine; Snape, Katie; Solano, Angela R; Soucy, Penny; Southey, Melissa C; Spurdle, Amanda B; Steele, Linda; Steinemann, Doris; Stoppa-Lyonnet, Dominique; Stradella, Agostina; Sunde, Lone; Sutter, Christian; Tan, Yen Y; Te

Long noncoding RNA MIR17HG promotes colorectal cancer progression via miR-17-5p

2019 - CANCER RESEARCH

Xu, J.; Meng, Q.; Li, X.; Yang, H.; Xu, J.; Gao, N.; Sun, H.; Wu, S.; Familiari, G.; Relucenti, M.; Zhu, H.; Wu, J.; Chen, R.

The promoter-associated noncoding RNA PNCCCND1_B assembles a proteinâRNA complex to regulate cyclin D1 transcription in Ewing sarcoma

2019 - CANCER RESEARCH

Palombo, R.; Frisone, P.; Fidaleo, M.; Mercatelli, N.; Sette, C.; Paronetto, M. P.

Targeting the chromosomal passenger complex subunit INCENP induces polyploidization, apoptosis, and senescence in neuroblastoma

2019 - CANCER RESEARCH

Sun, M.; Veschi, V.; Bagchi, S.; Xu, M.; Mendoza, A.; Liu, Z.; Thiele, C. J.

Targeting chromosomal passenger complex by disruption of INCENP function inhibits tumor progression in neuroblastoma

2019 - CANCER RESEARCH

Ming, Sun; Veschi, V; Norris, Lam; Sukriti, Bagchi; Man, Xu; Arnulfo, Mendoza; Zhihui, Liu; Carol, J Thiele

Targeting CDK6 and BCL2 exploits the "MYB addiction" of PhÃ¾acute lymphoblastic leukemia

2018 - CANCER RESEARCH

De Dominici, M; Porazzi, P; Soliera, Ar; Mariani, Sa; Addya, S; Fortina, P; Peterson, Lf; Spinelli, O; Rambaldi, A; Martinelli, G; Ferrari, A; Iacobucci, I; Calabretta, B.

Adoptive immunotherapy using prame-specific t cells in medulloblastoma

2018 - CANCER RESEARCH

Orlando, Domenico; Miele, Evelina; De Angelis, Biagio; Guercio, Marika; Boffa, Iolanda; Sinibaldi, Matilde; Po, Agnese; Caruana, Ignazio; Abballe, Luana; Carai, Andrea; Caruso, Simona; Camera, Antonio; Moseley, Annemarie; Hagedoorn, Renate S.; Heemskerk, Mirjam H. M.; Giangaspero, Felice; Mastronuzzi, Angela; Ferretti, Elisabetta; Locatelli, Franco; Quintarelli, Concetta

Efficacy of anti-EGFR rechallenge in RAS and BRAF wt metastatic colorectal cancer: Clinical and translational results of the phase II CRICKET study by GONO

2018 - CANCER RESEARCH

Rossini, D; Cremolini, C; Del Re, M; Lonardi, S; Busico, A; Rofi, E; Garattini, Sk; Tamburini, E; Dell'Aquila, E; Corsi, D; Bergamo, F; Barone, C; Masi, G; Pucci, F; Cattaneo, M; Pietrantonio, F; Perrone, F; Tonini, G; Santini, D; Falcone, A

Epigenetic siRNA and chemical screens identify SETD8 inhibition as a therapeutic strategy to reactivate p53 in high-risk neuroblastoma

2017 - CANCER RESEARCH

Veschi, V; Zhihui, Liu; Ty, C Voss; Laurent, Ozbun; Berkley, Gryder; Chunhua, Yan; Ying, Hu; Anqi, Ma; Jian, Jin; Sharlyn, J Mazur; Norris, Lam; Barbara, K Souza; Giuseppe, Giannini; Gordon, L Hager; Cheryl, H Arrowsmith; Javed, Khan; Ettore, Appella; Carol, Thiele

Abstract 1437: Relationship of G-CSF related bone pain (BP) with Bv8/PK2 expression in breast cancer (BC) patients (pts) treated with FEC100 adjuvant chemotherapy (CT)

2016 - CANCER RESEARCH

Rossi, Luigi; Papa, Anselmo; Tomao, Federica; Negri, Lucia; Tomao, Silverio