Pubblicazioni

A single buried cysteine acts as a hydrophobic stabilizer of a folding intermediate and transition state in the MATH domain of SPOP

2025 - PROTEIN SCIENCE

Pagano, Livia; Diop, Awa; Pennacchietti, Valeria; Di Felice, Mariana; Ventura, Eduarda S.; Toso, Julian; Toto, Angelo; Gianni, Stefano

Identification of the pyridoxal 5â²âphosphate allosteric site in human pyridox(am)ine 5â²âphosphate oxidase

2024 - PROTEIN SCIENCE

Barile, Anna; Graziani, Claudio; Antonelli, Lorenzo; Parroni, Alessia; Fiorillo, Annarita; di Salvo, Martino Luigi; Ilari, Andrea; Giorgi, Alessandra; Rosignoli, Serena; Paiardini, Alessandro; Contestabile, Roberto; Tramonti, Angela

Ferritin-based disruptor nanoparticles: A novel strategy to enhance LDL cholesterol clearance via multivalent inhibition of PCSK9âLDL receptor interaction

2024 - PROTEIN SCIENCE

Incocciati, A.; Cappelletti, C.; Masciarelli, S.; Liccardo, F.; Piacentini, R.; Giorgi, A.; Bertuccini, L.; De Berardis, B.; Fazi, F.; Boffi, A.; Bonamore, A.; Macone, A.

A PDZ tandem repeat folds and unfolds via different pathways

2024 - PROTEIN SCIENCE

Pennacchietti, Valeria; di Matteo, Sara; Pagano, Livia; Toplek, Fran BaÄiÄ; Stegani, Bruno; Toto, Angelo; Toso, Julian; Puglisi, Elena; Capelli, Riccardo; Di Felice, Mariana; MalagrinÃ², Francesca; Camilloni, Carlo; Gianni, Stefano

The ubiquitous pyridoxal 5'-phosphate-binding protein is also an RNA-binding protein

2024 - PROTEIN SCIENCE

Graziani, Claudio; Barile, Anna; Parroni, Alessia; di Salvo, Martino Luigi; De Cecio, Irene; Colombo, Teresa; Babor, Jill; de CrÃ©cy-Lagard, ValÃ©rie; Contestabile, Roberto; Tramonti, Angela

An intramolecular energetic network regulates ligand recognition in a SH2 domain

2023 - PROTEIN SCIENCE

Nardella, Caterina; Pagano, Livia; Pennacchietti, Valeria; Felice, Mariana Di; Matteo, Sara Di; Diop, Awa; MalagrinÃ², Francesca; Marcocci, Lucia; Pietrangeli, Paola; Gianni, Stefano; Toto, Angelo

Hydrophobicityâenhanced ferritin nanoparticles for efficient encapsulation and targeted delivery of hydrophobic drugs to tumor cells

2023 - PROTEIN SCIENCE

Incocciati, Alessio; KubeÅ¡, Jan; Piacentini, Roberta; Cappelletti, Chiara; Botta, Sofia; Bertuccini, Lucia; Å imÅ¯nek, TomÃ¡Å¡; Boffi, Alberto; Macone, Alberto; Bonamore, Alessandra

Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase

2022 - PROTEIN SCIENCE

Dindo, Mirco; Pascarelli, Stefano; Chiasserini, Davide; Grottelli, Silvia; Costantini, Claudio; Uechi, GenâIchiro; Giardina, Giorgio; Laurino, Paola; Cellini, Barbara

Characterization of early and late transition states of the folding pathway of a SH2 domain

2022 - PROTEIN SCIENCE

Toto, Angelo; MalagrinÃ², Francesca; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Santorelli, Daniele; Diop, Awa; Gianni, Stefano

Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat

2022 - PROTEIN SCIENCE

MalagrinÃ², Francesca; Fusco, Giuliana; Pennacchietti, Valeria; Toto, Angelo; Nardella, Caterina; Pagano, Livia; de Simone, Alfonso; Gianni, Stefano

Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability

2022 - PROTEIN SCIENCE

Tramonti, Angela; Ghatge, Mohini S; Babor, Jill T; Musayev, Faik N; di Salvo, Martino Luigi; Barile, Anna; Colotti, Gianni; Giorgi, Alessandra; Paredes, Steven D; Donkor, Akua K; Al Mughram, Mohammed H; de CrÃ©cy-Lagard, ValÃ©rie; Safo, Martin K; Contestabile, Roberto

From Kuru to Alzheimer: a personal outlook

2021 - PROTEIN SCIENCE

Brunori, Maurizio

Determining folding and binding properties of the C-terminal SH2 domain of SHP2

2021 - PROTEIN SCIENCE

Nardella, Caterina; MalagrinÃ², Francesca; Pagano, Livia; Rinaldo, Serena; Gianni, Stefano; Toto, Angelo

Comparing the binding properties of peptides mimicking the envelope protein of sars-cov and sars-cov-2 to the pdz domain of the tight junction-associated pals1 protein

2020 - PROTEIN SCIENCE

Toto, Angelo; Ma, Sana; MalagrinÃ², Francesca; Visconti, Lorenzo; Pagano, Livia; Stromgaard, Kristian; Gianni, Stefano

Effects of Y361-auto-phosphorylation on structural plasticity of the HIPK2 kinase domain

2018 - PROTEIN SCIENCE

Scaglione, Antonella; Monteonofrio, Laura; Parisi, Giacomo; Cecchetti, Cristina; Siepi, Francesca; Rinaldo, Cinzia; Giorgi, Alessandra; Verzili, Daniela; Zamparelli, Carlotta; Savino, Carmelinda; Soddu, Silvia; Vallone, Beatrice; Montemiglio, Linda Celeste