Pubblicazioni

Human estrogen receptor Î± antagonists, part 2: Synthesis driven by rational design, in vitro antiproliferative, and in vivo anticancer evaluation of innovative coumarin-related antiestrogens as breast cancer suppressants

2022 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Kurtanovic, N.; Tomasevic, N.; Matic, S.; Mitrovic, M. M.; Kostic, D. A.; Sabatino, M.; Antonini, L.; Ragno, R.; Mladenovic, M.

Novel Insights on Human Carbonic Anhydrase Inhibitors Based on Coumalic Acid: Design, Synthesis, Molecular Modeling Investigation, and Biological Studies

2022 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pontecorvi, Virginia; Mori, Mattia; Picarazzi, Francesca; Zara, Susi; Carradori, Simone; Cataldi, Amelia; Angeli, Andrea; Berrino, Emanuela; Chimenti, Paola; Ciogli, Alessia; Secci, Daniela; Guglielmi, Paolo; Supuran, Claudiu T.

New 1 H âindoleâ2,3âdione 3âthiosemicarbazones with 3âsulfamoylphenyl moiety as selective carbonic anhydrase inhibitors

2022 - ARCHIV DER PHARMAZIE

Eraslanâelma, PÄ±nar; Akdemir, Atilla; Berrino, Emanuela; BozdaÄ, Murat; Supuran, Claudiu T.; KaralÄ±, NilgÃ¼n

Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 integrase and reverse transcriptase associated ribonuclease H inhibitors

2020 - ANTIVIRAL RESEARCH

Esposito, F.; Sechi, M.; Pala, N.; Sanna, A.; Koneru, P. C.; Kvaratskhelia, M.; Naesens, L.; Corona, A.; Grandi, N.; di Santo, R.; D'Amore, V. M.; Di Leva, F. S.; Novellino, E.; Cosconati, S.; Tramontano, E.

Catechols: A new class of carbonic anhydrase inhibitors

2020 - CHEMICAL COMMUNICATIONS

D'Ambrosio, K.; Carradori, S.; Cesa, S.; Angeli, A.; Monti, S. M.; Supuran, C. T.; De Simone, G.

Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis

2019 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Di Paolo, V.; Fulci, C.; Rotili, D.; Sciarretta, F.; Lucidi, A.; Morozzo della Rocca, B.; De Luca, A.; Rosato, A.; Quintieri, L.; Caccuri, A. M.

Efficient synthesis and first regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold and their evaluation in H2O2-induced oxidative stress

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Loubidi, Mohammed; Jouha, Jabrane; Tber, Zahira; Khouili, Mostafa; Suzenet, Franck; Akssira, Mohamed; Erdogan, MÃ¼min Alper; KÃ¶se, Fadime AydÄ±n; DagcÄ±, Taner; Armagan, GÃ¼liz; Saso, Luciano; Guillaumet, GÃ©rald

9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-xanthene-3-one is a potentially novel antiplatelet drug which antagonizes the effect of thromboxane A2

2018 - MEDICINAL CHEMISTRY

ApplovÃ¡, Lenka; VeljoviÄ, Elma; MuratoviÄ, Samija; KarlÃÄkovÃ¡, Jana; MacÃ¡kovÃ¡, KateÅina; ZavrÅ¡nik, Davorka; Saso, Luciano; DuriÄ, Kemal; MladÄnka, PÅemysl

Oregonin from Alnus incana bark affects DNA methyltransferases expression and mitochondrial DNA copies in mouse embryonic fibroblasts

2018 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Krasilnikova, Jelena; Lauberte, Liga; Stoyanova, Elena; Abadjieva, Desislava; Chervenkov, Mihail; Mori, Mattia; De Paolis, Elisa; Mladenova, Vanya; Telysheva, Galina; Botta, Bruno; Kistanova, Elena

Leveraging the cruzain S3 subsite to increase affinity for reversible covalent inhibitors

2018 - BIOORGANIC CHEMISTRY

Cianni, Lorenzo; Sartori, Geraldo; Rosini, Fabiana; De Vita, Daniela; Pires, Gabriel; Lopes, Bianca Rebelo; LeitÃ£o, Andrei; Burtoloso, Antonio C B; Montanari, Carlos A

Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae Î±- and Î²-class enzymes

2018 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Bua, Silvia; Berrino, Emanuela; Del Prete, Sonia; Murthy, Vallabhaneni S; Vijayakumar, Vijayaparthasarathi; Tamboli, Yasinalli; Capasso, Clemente; Cerbai, Elisabetta; Mugelli, Alessandro; Carta, Fabrizio; Supuran, Claudiu T

Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: evaluation of antimicrobial, cytotoxic and hemolytic activities

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Merlino, Francesco; Carotenuto, Alfonso; Casciaro, Bruno; Martora, Francesca; Loffredo, MARIA ROSA; DI GRAZIA, Antonio; Yousif, Ali M.; Brancaccio, Diego; Palomba, Luciana; Novellino, Ettore; Galdiero, Massimiliano; Iovene, Maria Rosaria; Mangoni, Maria Luisa; Grieco, Paolo

Enzyme kinetics and inhibition of histone acetyltransferase KAT8

2015 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Wapenaar, Hannah; van der Wouden, Petra E; Groves, Matthew R; Rotili, Dante; Mai, Antonello; Dekker, Frank J.