Pubblicazioni

The binding selectivity of the C-terminal SH3 domain of Grb2, but not its folding pathway, is dictated by its contiguous SH2 domain

2024 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Di Felice, Mariana; Pagano, Livia; Pennacchietti, Valeria; Diop, Awa; Pietrangeli, Paola; Marcocci, Lucia; Di Matteo, Sara; Malagrinò, Francesca; Toto, Angelo; Gianni, Stefano

Understanding the molecular basis of folding cooperativity through a comparative analysis of a multidomain protein and its isolated domains

2023 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Santorelli, Daniele; Marcocci, Lucia; Pennacchietti, Valeria; Nardella, Caterina; Diop, Awa; Pietrangeli, Paola; Pagano, Livia; Toto, Angelo; Malagrino, Francesca; Gianni, Stefano

Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase

2021 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Barile, Anna; Battista, Theo; Fiorillo, Annarita; Luigi di Salvo, Martino; Malatesta, Francesco; Tramonti, Angela; Ilari, Andrea; Contestabile, Roberto

Templated folding of intrinsically disordered proteins

2020 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Toto, Angelo; Malagrinò, Francesca; Visconti, Lorenzo; Troilo, Francesca; Pagano, Livia; Brunori, Maurizio; Jemth, Per; Gianni, Stefano

A soluble derivative of PrPC activates cell-signaling and regulates cell physiology through LRP1 and the NMDA receptor

2020 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Mantuano, Elisabetta; Azmoon, Pardis; Banki, Michael A; Lam, Michael S; Sigurdson, Christina J; Gonias, Steven L

Allosteric feedback inhibition of pyridoxine 5'-phosphate oxidase from escherichia coli

2019 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Barile, A.; Tramonti, A.; Di Salvo, M. L.; Nogues, I.; Nardella, C.; Malatesta, F.; Contestabile, R.

A structurally heterogeneous transition state underlies coupled binding and folding of disordered proteins

2019 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Karlsson, E; Andersson, E; Dogan, J.; Gianni, S.; Jemth, P.; Camilloni, C.

PLK1 targets NOTCH1 during DNA damage and mitotic progression

2019 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
De Blasio, Carlo; Zonfrilli, A.; Franchitto, Matteo; Mariano, G.; Cialfi, S.; Verma, Nagendra; Checquolo, S.; Bellavia, D.; Palermo, R.; Benelli, D.; Screpanti, I.; Talora, C.

Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD

2018 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Del Caño-Ochoa, Francisco; Grande-García, Araceli; Reverte-López, María; D'Abramo, Marco; Ramón-Maiques, Santiago

Functional analyses yield detailed insight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae

2017 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Pirone, Luciano; Ripoll-Rozada, Jorge; Leone, Marilisa; Ronca, Raffaele; Lombardo, Fabrizio; Fiorentino, Gabriella; Andersen, John F.; Pereira, Pedro José Barbosa; Arcà, Bruno; Pedone, Emilia

Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes

2017 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Oka, Shin-Ichi; Hirata, Tsuyoshi; Suzuki, Wataru; Naito, Daichi; Chen, Yanbin; Chin, Adave; Yaginuma, Hiroaki; Saito, Toshiro; Nagarajan, Narayani; Zhai, Peiyong; Bhat, Santosh; Schesing, Kevin; Shao, Dan; Hirabayashi, Yoko; Yodoi, Junji; Sciarretta, Sebastiano; Sadoshima, Junichi

Nuclear Factor of Activated T Cells-dependent Down-regulation of the Transcription Factor Glioma-associated Protein 1 (GLI1) Underlies the Growth Inhibitory Properties of Arachidonic Acid

2016 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Comba, Andrea; Almada Luciana, L; Tolosa Ezequiel, J.; Iguchi, Eriko; Marks David, L.; Vara, Messler Mariangela; Silva, Renata; Fernandez Barrena Maite, G.; Enriquez Hesles, Elisa; Vrabel Anne, L; Botta, Bruno; Di Marcotullio, Lucia; Ellenrieder, Volker; Eynard Aldo, R; Pasqualini Maria, E.; Fernandez Zapico Martin, E.

S-adenosyl-L-methionine modulates CO and NO· binding to the human H2S-generating enzyme cystathionine β-synthase

2016 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Vicente, João B; Colaço, Henrique G.; Sarti, Paolo; Leandro, Paula; Giuffre', Alessandro

Identification and structural characterization of an intermediate in the folding of the measles virus x domain

2016 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Bonetti, Daniela; Camilloni, Carlo; Visconti, Lorenzo; Longhi, Sonia; Brunori, Maurizio; Vendruscolo, Michele; Gianni, Stefano

Structural Characterization of the Extracellular Domain of CASPR2 and Insights into Its Association with the Novel Ligand Contactin1

2016 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Rubio Marrero, Eva N.; Vincelli, Gabriele; Jeffries, Cy M.; Shaikh, Tanvir R.; Pakos, Irene S.; Ranaivoson, Fanomezana M.; Daake, Sventja von; Demeler, Borries; DE JACO, Antonella; Perkins, Guy; Ellisman, Mark H.; Trewhella, Jill; Comoletti, Davide

Transfected poly(I:C) activates different dsRNA receptors leading to apoptosis or immunoadjuvant response in androgen-independent prostate cancer cells

2015 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
PALCHETTI, SARA; STARACE, Donatella; P., De Cesaris; FILIPPINI, Antonio; ZIPARO, Elio; RICCIOLI, ANNA

Engineering a nickase on the homing endonuclease I-DmoI scaffold

2015 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Molina, Rafael; Marcaida, María José; Redondo, Pilar; Marenchino, Marco; Duchateau, Phillippe; D'Abramo, Marco; Montoya, Guillermo; Prieto, Jesús

New insights on the mechanism of quinoline-based DNA methyltransferase inhibitors

2015 - THE JOURNAL OF BIOLOGICAL CHEMISTRY
Gros, Christina; Fleury, Laurence; Nahoum, Virginie; Faux, Céline; Valente, Sergio; Labella, Donatella; Cantagrel, Frédéric; Rilova, Elodie; Bouhlel, Mohamed Amine; David Cordonnier, Marie Hélène; Dufau, Isabelle; Ausseil, Frédéric; Mai, Antonello; Mourey, Lionel; Lacroix, Laurent; Arimondo, Paola B.

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