Pubblicazioni

FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation

2021 - SCIENCE ADVANCES

Birsa, N.; Ule, A. M.; Garone, M. G.; Tsang, B.; Mattedi, F.; Andrew Chong, P.; Humphrey, J.; Jarvis, S.; Pisiren, M.; Wilkins, O. G.; Nosella, M. L.; Devoy, A.; Bodo, C.; De la Fuente, R. F.; Fisher, E. M. C.; Rosa, A.; Viero, G.; Forman-Kay, J. D.; Schiavo, G.; Fratta, P.

Progression of oropharyngeal dysphagia in amyotrophic lateral sclerosis: a retrospective cohort study

2021 - DYSPHAGIA

Mariani, L.; Ruoppolo, G.; Cilfone, A.; Cocchi, C.; Preziosi Standoli, Jacopo; Longo, L.; Ceccanti, Marco; Greco, A.; Inghilleri, M.

PREVALENCE OF AMYOTROPHIC LATERAL SCLEROSIS IN LATIUM REGION (ITALY)

2021 - BRAIN AND BEHAVIOR

Puopolo, Maria; Bacigalupo, Ilaria; Piscopo, Paola; Lacorte, Eleonora; Di Pucchio, Alessandra; Santarelli, Marialaura; Inghilleri, Maurizio; Petrucci, Antonio; Sabatelli, Mario; Vanacore, Nicola; Libonati, Laura; Ceccanti, Marco

The unfolded protein response in amyotrophic later sclerosis. results of a phase 2 trial

2021 - BRAIN

Bella, Eleonora Dalla; Bersano, Enrica; Antonini, Giovanni; Borghero, Giuseppe; Capasso, Margherita; Caponnetto, Claudia; ChiÃ², Adriano; Corbo, Massimo; Filosto, Massimiliano; Giannini, Fabio; Spataro, Rossella; Lunetta, Christian; Mandrioli, Jessica; Messina, Sonia; MonsurrÃ², Maria Rosaria; Mora, Gabriele; Riva, Nilo; Rizzi, Romana; Siciliano, Gabriele; Silani, Vincenzo; Simone, Isabella; SorarÃ¹, Gianni; Tugnoli, Valeria; Verriello, Lorenzo; Volanti, Paolo; Furlan, Roberto; Nolan, John M; Abgueguen, Emmanuelle; Tramacere, Irene; Lauria, Giuseppe

Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition

2021 - STEM CELL REPORTS

Stoklund Dittlau, K.; Krasnow, E. N.; Fumagalli, L.; Vandoorne, T.; Baatsen, P.; Kerstens, A.; Giacomazzi, G.; Pavie, B.; Rossaert, E.; Beckers, J.; Sampaolesi, M.; Van Damme, P.; Van Den Bosch, L.

Drug Repurposing: A Network-based Approach to Amyotrophic Lateral Sclerosis

2021 - NEUROTHERAPEUTICS

Fiscon, G.; Conte, F.; Amadio, S.; Volonte, C.; Paci, P.

Creatine kinase and progression rate in amyotrophic lateral sclerosis

2020 - CELLS

Ceccanti, Marco; Pozzilli, Valeria; Cambieri, Chiara; Libonati, Laura; Onesti, Emanuela; Frasca, Vittorio; Fiorini, Ilenia; Petrucci, Antonio; Garibaldi, Matteo; Palma, Eleonora; Bendotti, Caterina; Fabbrizio, Paola; Chiara Trolese, Maria; Nardo, Giovanni; Inghilleri, Maurizio

RNA as a key factor in driving or preventing self-assembly of the TAR DNA-binding protein 43

2019 - JOURNAL OF MOLECULAR BIOLOGY

Zacco, Elsa; GraÃ±a-Montes, Ricardo; Martin, Stephen R; de Groot, Natalia Sanchez; Alfano, Caterina; Tartaglia, Gian Gaetano; Pastore, Annalisa

Psychodynamic insights from narratives of people with amyotrophic lateral sclerosis: a qualitative phenomenological study

2019 - MEDITERRANEAN JOURNAL OF CLINICAL PSYCHOLOGY

Caputo, A.

Modulation of human corticospinal excitability by paired associative stimulation in patients with amyotrophic lateral sclerosis and effects of Riluzole

2018 - BRAIN STIMULATION

Ceccanti, M; Onesti, E; Rubino, A; Cambieri, C; Tartaglia, Giorgio; Miscioscia, A; Frasca, V; Inghilleri, M.

On the relationship between attention processing and P300-based brain computer interface control in amyotrophic lateral sclerosis

2018 - FRONTIERS IN HUMAN NEUROSCIENCE

Riccio, Angela; Schettini, Francesca; Simione, Luca; Pizzimenti, Alessia; Inghilleri, Maurizio; Olivetti, Marta; Mattia, Donatella; Cincotti, Febo

Direct conversion of human pluripotent stem cells into cranial motor neurons using a piggyBac vector

2018 - STEM CELL RESEARCH

De Santis, Riccardo; Garone, Maria Giovanna; Pagani, Francesca; de Turris, Valeria; Di Angelantonio, Silvia; Rosa, Alessandro

Effects of class II-selective histone deacetylase inhibitor on neuromuscular function and disease progression in SOD1-ALS mice

2018 - NEUROSCIENCE

Buonvicino, Daniela; Felici, Roberta; Ranieri, Giuseppe; Caramelli, Riccardo; Lapucci, Andrea; Cavone, Leonardo; Muzzi, Mirko; Di Pietro, Lorena; Bernardini, Camilla; Zwergel, Clemens; Valente, Sergio; Mai, Antonello; Chiarugi, Alberto

Background-deflection Brillouin microscopy reveals altered biomechanics of intracellular stress granules by ALS protein FUS

2018 - COMMUNICATIONS BIOLOGY

Antonacci, Giuseppe; DE TURRIS, Valeria; Rosa, Alessandro; Ruocco, Giancarlo

Therapeutic strategies under development targeting inflammatory mechanisms in amyotrophic lateral sclerosis

2018 - MOLECULAR NEUROBIOLOGY

Crisafulli, Sebastiano Giuseppe; Brajkovic, Simona; Cipolat Mis, Maria Sara; Parente, Valeria; Corti, Stefania

Differential toxicity of TAR DNA-binding protein 43 isoforms depends on their submitochondrial localization in neuronal cells

2018 - JOURNAL OF NEUROCHEMISTRY

Salvatori, I.; Ferri, A.; Scaricamazza, S.; Giovannelli, I.; Serrano, A.; Rossi, S.; D'Ambrosi, N.; Cozzolino, M.; Giulio, A. D.; Moreno, S.; Valle, C.; Carri, M. T.

Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice (vol 7, 2033, 2017)

2018 - SCIENTIFIC REPORTS

Mirra, A; Rossi, S; Scaricamazza, S; Di Salvio, M; Salvatori, I; Valle, C; Rusmini, P; Poletti, A; Cestra, G; Carri, Mt; Cozzolino, M

Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of Alzheimer disease and other selected age-related neurodegenerative disorders

2017 - FREE RADICAL BIOLOGY & MEDICINE

Di Domenico, Fabio; Tramutola, Antonella; Butterfield, D. Allan

Dysphagia in amyotrophic lateral sclerosis: impact on patient behavior, diet adaptation, and riluzole management

2017 - FRONTIERS IN NEUROLOGY

ONESTI, EMANUELA; SCHETTINO, ILENIA; Gori, Mc; FRASCA, VITTORIO; CECCANTI, MARCO; CAMBIERI, CHIARA; RUOPPOLO, Giovanni; INGHILLERI, Maurizio

FUS mutant human motoneurons display altered transcriptome and microRNA pathways with implications for ALS pathogenesis

2017 - STEM CELL REPORTS

DE SANTIS, Riccardo; Santini, Laura; Colantoni, Alessio; Peruzzi, Giovanna; DE TURRIS, Valeria; Alfano, Vincenzo; Bozzoni, Irene; Rosa, Alessandro

Protein misfolding, amyotrophic lateral sclerosis and guanabenz. Protocol for a phase II RCT with futility design (ProMISe trial)

2017 - BMJ OPEN

Bella, Eleonora Dalla; Tramacere, Irene; Antonini, Giovanni; Borghero, Giuseppe; Capasso, Margherita; Caponnetto, Claudia; ChiÃ², Adriano; Corbo, Massimo; Eleopra, Roberto; Filosto, Massimiliano; Giannini, Fabio; Granieri, Enrico; Bella, Vincenzo La; Lunetta, Christian; Mandrioli, Jessica; Mazzini, Letizia; Messina, Sonia; MonsurrÃ², Maria Rosaria; Mora, Gabriele; Riva, Nilo; Rizzi, Romana; Siciliano, Gabriele; Silani, Vincenzo; Simone, Isabella; SorarÃ¹, Gianni; Volanti, Paolo; Lauria, Giuseppe

Imaging techniques in ALS

2017 - ARCHIVES ITALIENNES DE BIOLOGIE

Zaccagna, F.; Lucignani, G.; Colonnese, C.

Motor neuron degeneration in spastic paraplegia 11 mimics amyotrophic lateral sclerosis lesions

2016 - BRAIN

Denora, Paola S.; Smets, Katrien; Zolfanelli, Federica; Groote, Chantal Ceuterick De; Casali, Carlo; Deconinck, Tine; Sieben, Anne; Gonzales, Michael; Zuchner, Stephan; Darios, Frederic; Peeters, Dirk; Brice, Alexis; Malandrini, Alessandro; De Jonghe, Peter; Santorelli, Filippo M.; Stevanin, Giovanni; Martin, Jean Jacques; El Hachimi, Khalid H.

Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis

2016 - SKELETAL MUSCLE

Beqollari, Donald; Romberg, Christin F.; Dobrowolny, Gabriella; Martini, Martina; Voss, Andrew A.; MusarÃ², Antonio; Bannister, Roger A.

Nuclear accumulation of mrnas underlies g4c2 repeat-induced translational repression in a cellular model of c9orf72 als

2015 - JOURNAL OF CELL SCIENCE

S., Rossi; A., Serrano; V., Gerbino; Giorgi, Alessandra; Di Francesco, Laura; M., Nencini; F., Bozzo; Schinina', Maria Eugenia; C., Bagni; G., Cestra; M. T., CarrÃ¬; T., Achsel; M., Cozzolino