Pubblicazioni

AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway

2024 - BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE

Naso, Francesco Davide; Polverino, Federica; Cilluffo, Danilo; Latini, Linda; Stagni, Venturina; Asteriti, Italia Anna; Rosa, Alessandro; Soddu, Silvia; Guarguaglini, Giulia

P53: A key player in diverse cellular processes including nuclear stress and ribosome biogenesis, highlighting potential therapeutic compounds

2024 - BIOCHEMICAL PHARMACOLOGY

Temaj, Gazmend; Chichiarelli, Silvia; Telkoparan-Akillilar, Pelin; Saha, Sarmistha; Nuhii, Nexhibe; Hadziselimovic, Rifat; Saso, Luciano

NRF2 activation in BONâ1 neuroendocrine cancerÂ cells reduces the cytotoxic effects of a novel Ruthenium(II)âcurcumin compound: A pilot study

2024 - ONCOLOGY REPORTS

Garufi, Alessia; Pettinari, Riccardo; Monteonofrio, Laura; Puliani, Giulia; Virdia, Ilaria; Appetecchia, Marialuisa; Marchetti, Fabio; Cirone, Mara; Soddu, Silvia; D'Orazi, Gabriella

EZH2 Inhibition by DS3201 triggers the kaposiâs sarcoma-associated herpesvirus lytic cycle and potentiates the effects induced by SAHA in primary effusion lymphoma cells

2024 - VIRUSES

Gonnella, Roberta; Collura, Flavia; Corrado, Vincenzo; Di Crosta, Michele; Santarelli, Roberta; Cirone, Mara

Resection of supratentorial high-grade gliomas availing of neuronavigation matched intraoperative ultrasound and Fluorescein: How far is it safe to push the resection?

2024 - WORLD NEUROSURGERY. X

Pesce, Alessandro; Palmieri, Mauro; Pietrantonio, Andrea; Ciarlo, Silvia; Salvati, Maurizio; Pompucci, Angelo

The Sweet Side of HIPK2

2023 - CANCERS

Garufi, Alessia; D'Orazi, Valerio; Pistritto, Giuseppa; Cirone, Mara; DâOrazi, Gabriella

The Multiple Faces of the MRN Complex: Roles in Medulloblastoma and Beyond

2023 - CANCERS

Petroni, Marialaura; LA MONICA, Veronica; Fabretti, Francesca; Augusto, Mariaconcetta; Battaglini, Damiana; Polonara, Francesca; DI GIULIO, Stefano; Giannini, Giuseppe

Interpretation of missense variants found in association with cancer

2023 - Encyclopedia of life science

Chiaraluce, Roberta; Consalvi, Valerio

HIPK2 in Angiogenesis: A Promising Biomarker in Cancer Progression and in Angiogenic Diseases

2023 - CANCERS

Garufi, Alessia; D'Orazi, Valerio; Pistritto, Giuseppa; Cirone, Mara; D'Orazi, Gabriella

DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication

2022 - BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Arena, A.; Gilardini Montani, M. S.; Romeo, M. A.; Benedetti, R.; Gaeta, A.; Cirone, M.

Functional Domains of the Early Proteins and Experimental and Epidemiological Studies Suggest a Role for the Novel Human Polyomaviruses in Cancer.

2022 - FRONTIERS IN MICROBIOLOGY

Moens, Ugo; Prezioso, Carla; Pietropaolo, Valeria Antonietta

Zinc Supplementation Enhances the Pro-Death Function of UPR in Lymphoma Cells Exposed to Radiation

2022 - BIOLOGY

Gonnella, Roberta; Guttieri, Luisa; Gilardini Montani, Maria Saveria; Santarelli, Roberta; Bassetti, Erica; D'Orazi, Gabriella; Cirone, Mara

NRF2 in Cancer: Cross-Talk with Oncogenic Pathways and Involvement in Gammaherpesvirus-Driven Carcinogenesis

2022 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cirone, Mara; D'Orazi, Gabriella

A homogeneous treatment for non-DIPG diffuse midline glioma

2022 - TUMORI

Schiavello, Elisabetta; Biassoni, Veronica; Gattuso, Giovanna; Podda, Marta; Chiaravalli, Stefano; Barretta, Francesco; Antonelli, Manila; De Cecco, Loris; Pecori, Emilia; Gandola, Lorenza; Massimino, Maura

Role of upr sensor activation in cell deathâsurvival decision of colon cancer cells stressed by dpe treatment

2021 - BIOMEDICINES

Benedetti, R.; Gilardini Montani, M. S.; Romeo, M. A.; Arena, A.; Santarelli, R.; D'orazi, G.; Cirone, M.

p53 Activation Effect in the Balance of T Regulatory and Effector Cell Subsets in Patients With Thyroid Cancer and Autoimmunity

2021 - FRONTIERS IN IMMUNOLOGY

Arena, A.; Stigliano, A.; Belcastro, E.; Giorda, E.; Rosado, M. M.; Grossi, A.; Assenza, M. R.; Moretti, F.; Fierabracci, A.

Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53

2021 - EXPERIMENTAL CELL RESEARCH

Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Arena, A.; Maretto, M.; Bassetti, E.; Caiazzo, R.; D'Orazi, G.; Cirone, M.

IDH wild-type glioblastoma presenting with seizure: clinical specificity, and oncologic and surgical outcomes

2021 - JOURNAL OF NEUROLOGICAL SURGERY. PART A, CENTRAL EUROPEAN NEUROSURGERY

Pesce, A.; Armocida, D.; Paglia, F.; Palmieri, M.; Frati, A.; D'Andrea, G.; Salvati, M.; Santoro, A.

CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme

2021 - EUROPEAN JOURNAL OF PHARMACOLOGY

Daniele, S.; La Pietra, V.; Piccarducci, R.; Pietrobono, D.; Cavallini, C.; D'Amore, V. M.; Cerofolini, L.; Giuntini, S.; Russomanno, P.; Puxeddu, M.; Nalli, M.; Pedrini, M.; Fragai, M.; Luchinat, C.; Novellino, E.; Taliani, S.; La Regina, G.; Silvestri, R.; Martini, C.; Marinelli, L.

Lovastatin reduces PEL cell survival by phosphorylating ERK1/2 that blocks the autophagic flux and engages a cross-talk with p53 to activate p21

2021 - IUBMB LIFE

Santarelli, R.; Pompili, C.; Gilardini Montani, M. S.; Romeo, M. A.; Gonnella, R.; D'Orazi, G.; Cirone, M.

P62/sqstm1/keap1/nrf2 axis reduces cancer cells death-sensitivity in response to zn(Ii)âcurcumin complex

2021 - BIOMOLECULES

Garufi, A.; Giorno, E.; Gilardini Montani, M. S.; Pistritto, G.; Crispini, A.; Cirone, M.; D'orazi, G.

Specific Protein 1 and p53 Interplay Modulates the Expression of the KCTD-Containing Cullin3 Adaptor Suppressor of Hedgehog 2

2021 - FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Angrisani, A.; Di Fiore, A.; Di Trani, C. A.; Fonte, S.; Petroni, M.; Lospinoso Severini, L.; Bordin, F.; Belloni, L.; Ferretti, E.; Canettieri, G.; Moretti, M.; De Smaele, E.

Interplay between endoplasmic reticulum (ER) stress and autophagy induces mutant p53H273 degradation

2020 - BIOMOLECULES

Garufi, Alessia; Federici, Giulia; Gilardini Montani, Maria Saveria; Crispini, Alessandra; Cirone, Mara; D'Orazi, Gabriella

A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status

2020 - JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Garufi, Alessia; Baldari, Silvia; Pettinari, Riccardo; Gilardini Montani, Maria Saveria; D'Orazi, Valerio; Pistritto, Giuseppa; Crispini, Alessandra; Giorno, Eugenia; Toietta, Gabriele; Marchetti, Fabio; Cirone, Mara; D'Orazi, Gabriella

Inhibition of Eukaryotic Translation Initiation Factor 5A (eIF5A) Hypusination Suppress p53 Translation and Alters the Association of eIF5A to the Ribosomes

2020 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Martella, Marianna; Catalanotto, Caterina; Talora, Claudio; La Teana, Anna; Londei, Paola; Benelli, Dario