Pubblicazioni

Computational evidences of a misfolding event in an aggregationâprone light chain preceding the formation of the nonânative pathogenic dimer

2024 - PROTEINS

Desantis, Fausta; Miotto, Mattia; Milanetti, Edoardo; Ruocco, Giancarlo; DI RIENZO, Lorenzo

RNA sequestration driven by amyloid formation: the alpha synuclein case

2023 - NUCLEIC ACIDS RESEARCH

Rupert, Jakob; Monti, Michele; Zacco, Elsa; Tartaglia, GIAN GAETANO

Mitochondria inter-organelle relationships in cancer protein aggregation

2022 - FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Genovese, Ilaria; Fornetti, Ersilia; Ruocco, Giancarlo

Serpin neuropathology in the P497S UBQLN2 mouse model of ALS/FTD

2021 - BRAIN PATHOLOGY

Higgins, N. R.; Greenslade, J. E.; J. J., Wu; Miranda, E.; Galliciotti, G.; Monteiro, M. J.

The Importance of N186 in the Alpha-1-Antitrypsin Shutter Region Is Revealed by the Novel Bologna Deficiency Variant

2021 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ronzoni, Riccardo; Ferrarotti, Ilaria; D'Acunto, Emanuela; Balderacchi, Alice M; Ottaviani, Stefania; Lomas, David A; Irving, James A; Miranda, Elena; Fra, Annamaria

Protein aggregation landscape in neurodegenerative diseases: clinical relevance and future applications

2021 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Candelise, N.; Scaricamazza, S.; Salvatori, I.; Ferri, A.; Valle, C.; Manganelli, V.; Garofalo, T.; Sorice, M.; Misasi, R.

Neuroserpin Inclusion Bodies in a FENIB Yeast Model

2021 - MICROORGANISMS

Vapore, Valentina; Mazzaglia, Corrado; Sibilia, Diego; Del Vecchio, Mara; Fruhmann, Gernot; Valenti, Marta; Miranda, Elena; Rinaldi, Teresa; Winderickx, Joris; Mazzoni, Cristina

The C-terminal region of yeast Ubiquitin-protein ligase Not4 mediates its cellular localization and stress response

2021 - FEMS MICROBIOLOGY LETTERS

Palermo, Vanessa; Stirpe, Mariarita; Bianchi, Michele Maria; Rinaldi, Teresa; Cirigliano, Angela; Ragnini-Wilson, Antonella; Falcone, Claudio; Mazzoni, Cristina

A computational approach to investigate tdp-43 rna-recognition motif 2 c-terminal fragments aggregation in amyotrophic lateral sclerosis

2021 - BIOMOLECULES

Grassmann, G.; Miotto, M.; Di Rienzo, L.; Salaris, F.; Silvestri, B.; Zacco, E.; Rosa, A.; Tartaglia, G. G.; Ruocco, G.; Milanetti, E.

mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder

2021 - FREE RADICAL BIOLOGY & MEDICINE

Perluigi, M.; Di Domenico, F.; Barone, E.; Butterfield, D. A.

RNA as the stone guest of protein aggregation

2020 - NUCLEIC ACIDS RESEARCH

Louka, Alexandra; Zacco, Elsa; Temussi, Piero Andrea; Tartaglia, Gian Gaetano; Pastore, Annalisa

RNA as a key factor in driving or preventing self-assembly of the TAR DNA-binding protein 43

2019 - JOURNAL OF MOLECULAR BIOLOGY

Zacco, Elsa; GraÃ±a-Montes, Ricardo; Martin, Stephen R; de Groot, Natalia Sanchez; Alfano, Caterina; Tartaglia, Gian Gaetano; Pastore, Annalisa

Homage to Chris Dobson

2019 - FRONTIERS IN MOLECULAR BIOSCIENCES

Baum, J.; Chiti, F.; De Simone, A.; Knowles, T. P. J.; Kumita, J. R.; Radford, S. E.; Robinson, C. V.; Salvatella, X.; Valelli, K.; Vendruscolo, M.; Pastore, A.; Tartaglia, G. G.

Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS

2017 - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ciryam, Prajwal; Lambert-Smith, Isabella A.; Bean, Daniel M.; Freer, Rosie; Cid, Fernando; Tartaglia, Gian Gaetano; Saunders, Darren N.; Wilson, Mark R.; Oliver, Stephen G.; Morimoto, Richard I.; Dobson, Christopher M.; Vendruscolo, Michele; Favrin, Giorgio; Yerbury, Justin J.

From redox proteomics to clinical practice: Search for therapeutic targets

2017 - JOURNAL OF GERONTOLOGY AND GERIATRICS

Di Domenico, F.; Cini, C.; Perluigi, M.

Toward a multilevel representation of protein molecules. Comparative approaches to the aggregation/folding propensity problem

2016 - INFORMATION SCIENCES

Livi, Lorenzo; Giuliani, Alessandro; Rizzi, Antonello

An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behavior

2016 - BIOCHEMICAL JOURNAL

Motamedi Shad, Neda; Jagger, Alistair M.; Liedtke, Maximilian; Faull, Sarah V.; Nanda, Arjun Scott; Salvadori, Enrico; Wort, Joshua L.; Kay, Christopher W. M.; Heyer Chauhan, Narinder; MIRANDA BANOS, MARIA ELENA; Perez, Juan; OrdÃ³Ã±ez, Adriana; Haq, Imran; Irving, James A.; Lomas, David A.

Structural insights into the multi-determinant aggregation of TDP-43 in motor neuron-like cells

2016 - NEUROBIOLOGY OF DISEASE

Bozzo, F.; Salvatori, I.; Iacovelli, F.; Mirra, A.; Rossi, S.; Cozzolino, M.; Falconi, M.; Valle, C.; Carri, M. T.

Interactions between N-linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum

2015 - THE FEBS JOURNAL

Moriconi, Claudia; OrdoÃ±ez, Adriana; Lupo, Giuseppe; Gooptu, Bibek; Irving, James A; Noto, Rosina; Martorana, Vincenzo; Manno, Mauro; Timpano, Valentina; Guadagno, NOEMI ANTONELLA; Dalton, Lucy; Marciniak, Stefan J; Lomas, David A; MIRANDA BANOS, MARIA ELENA