Pubblicazioni

UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response

2016 - ONCOTARGET

Signore, Michele; Buccarelli, Mariachiara; Pilozzi, Emanuela; De Luca, Gabriele; Cappellari, Marianna; Fanciulli, Maurizio; Goeman, Frauke; Melucci, Elisa; Biffoni, Mauro; Ricci Vitiani, Lucia

Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner

2016 - ONCOTARGET

Amantini, C; Morelli, MARIA BEATRICE; Nabissi, M; Cardinali, Claudio; Santoni, M; Gismondi, Angela; Santoni, G.

Cell surgery and growth factors in dry age-related macular degeneration: visual prognosis and morphological study

2016 - ONCOTARGET

Limoli, Paolo Giuseppe; Limoli, Celeste; Vingolo, Enzo Maria; Scalinci, Sergio Zaccaria; Nebbioso, Marcella

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells

2016 - ONCOTARGET

DI MARTILE, Marta; Desideri, Marianna; DE LUCA, Teresa; Gabellini, Chiara; Buglioni, Simonetta; Eramo, Adriana; Sette, Giovanni; Milella, MICHELE STANISLAW; Rotili, Dante; Mai, Antonello; Carradori, Simone; Secci, Daniela; De Maria, Ruggero; Del Bufalo, Donatella; Trisciuoglio, Daniela

Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition

2016 - ONCOTARGET

Lobello, N; Biamonte, Federica; Pisanu, Maria Elena; Faniello, Mc; Jakopin, Å½; Chiarella, E; Giovannone, Ed; Mancini, Rita; Ciliberto, G; Cuda, G; Costanzo, F.

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression

2016 - ONCOTARGET

Ciardiello, Chiara; Roca, Maria Serena; Noto, Alessia; Bruzzese, Francesca; Moccia, Tania; Vitagliano, Carlo; Di Gennaro, Elena; Ciliberto, Gennaro; Roscilli, Giuseppe; Aurisicchio, Luigi; Marra, Emaluele; Mancini, Rita; Budillon, Alfredo; Leone, Alessandra

Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease

2016 - ONCOTARGET

Simile, Maria M.; Latte, Gavinella; Demartis, Maria I.; Brozzetti, Stefania; Calvisi, Diego F.; Porcu, Alberto; Feo, Claudio F.; Seddaiu, Maria A.; Daino, Lucia; Berasain, Carmen; Tomasi, Maria L.; Avila, Matias A.; Feo, Francesco; Pascale, Rosa M.

Visceral fat adipocytes from obese and colorectal cancer subjects exhibit distinct secretory and Ï6 polyunsaturated fatty acid profiles and deliver immunosuppressive signals to innate immunity cells

2016 - ONCOTARGET

Del CornÃ², Manuela; D'Archivio, Massimo; Conti, Lucia; Scazzocchio, Beatrice; VarÃ¬, Rosaria; Donninelli, Gloria; Varano, Barbara; Giammarioli, Stefania; DE MEO, Simone; Silecchia, Gianfranco; PennestrÃ¬, Francesco; Persiani, Roberto; Masella, Roberta; Gessani, Sandra

Pre-treatment assay of 5-fluorouracil degradation rate (5-FUDR) to improve prediction of 5-fluorouracil toxicity in gastro-esophageal cancer

2016 - ONCOTARGET

Borro, Marina; Botticelli, Andrea; Mazzuca, Federica; Onesti, Elisa Concetta; Gentile, Giovanna; Romiti, Adriana; Cerbelli, Bruna; Mazzotti, Eva; Marchetti, Luca; Lionetto, Luana; Simmaco, Maurizio; Marchetti, Paolo

DNMT3B in vitro knocking-down is able to reverse embryonal rhabdomyosarcoma cell phenotype through inhibition of proliferation and induction of myogenic differentiation

2016 - ONCOTARGET

Megiorni, Francesca; Camero, Simona; Ceccarelli, Simona; Mcdowell, Heather P; Mannarino, Olga; Marampon, Francesco; Pizer, Barry; Shukla, Rajeev; Pizzuti, Antonio; Marchese, Cinzia; Clerico, Anna; Dominici, Carlo

The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA

2016 - ONCOTARGET

Mangiavacchi, Arianna; Sorci, Melissa; Masciarelli, Silvia; Larivera, Simone; Legnini, Ivano; Iosue', Ilaria; Bozzoni, Irene; Fazi, Francesco; Fatica, Alessandro

Functional single nucleotide polymorphisms within the cyclin-dependent kinase inhibitor 2A/2B region affect pancreatic cancer risk

2016 - ONCOTARGET

Campa D1, 2; Pastore, M; Gentiluomo, M; Talar Wojnarowska, R; Kupcinskas, J; Malecka Panas, E; Neoptolemos, Jp; Niesen, W; Vodicka, P; DELLE FAVE, Gianfranco; Bas Bueno de Mesquita, H; Gazouli, M; Pacetti, P; Di Leo, M; Ito, H; KlÃ¼ter, H; Soucek, P; Corbo, V; Yamao, K; Hosono, S; Kaaks, R; Vashist, Y; Gioffreda, D; Strobel, O; Shimizu, Y; Dijk, F; Andriulli, A; Ivanauskas, A; Bugert, P; Tavano, F; Vodickova, L; Federico Zambon, C; Lovecek, M; Landi, S; Key, Tj; Boggi, U; Pezzilli, R; Jamroziak, K; Mohelnikova Duchonova, B; Mambrini, A; Bambi, F; Busch, O; Pazienza, V; Valente, Roberto; Theodoropoulos, Ge; Hackert, T; Capurso, G; Martina Cavestro, G; Pasquali, C; Basso, D; Sperti, C; Matsuo, K; BÃ¼chler, M; Khaw, Kt; Izbicki, J; Costello, E; Katzke, V; Michalski, C; Stepien, A; Rizzato, C.

Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration.

2016 - ONCOTARGET

Nabissi, M; Morelli, MARIA BEATRICE; Offidani, M; Amantini, C; Gentili, S; Soriani, Alessandra; Cardinali, Claudio; Leoni, P; Santoni, G.

Somatic alterations of targetable oncogenes are frequently observed in BRCA1/2 mutation negative male breast cancers

2016 - ONCOTARGET

Rizzolo, Piera; Navazio, ANNA SARA; Silvestri, Valentina; Valentini, Virginia; Zelli, Veronica; Zanna, Ines; Masala, Giovanna; Bianchi, Simonetta; ScarnÃ², Marco; Tommasi, Stefania; Palli, Domenico; Ottini, Laura

Post-transcriptional regulation of 5'-untranslated regions of human Transient Receptor Potential Vanilloid type-1 (TRPV-1) channels: role in the survival of glioma patients.

2016 - ONCOTARGET

Nabissi, Massimo; Morelli, MARIA BEATRICE; Arcella, Antonietta; Cardinali, Claudio; Santoni, Matteo; Bernardini, Giovanni; Santoni, Angela; Santoni, Giorgio; Amantini, Consuelo

Hyperglycemia triggers HIPK2 protein degradation

2016 - ONCOTARGET

Baldari, Silvia; Garufi, Alessia; Granato, Marisa; Cuomo, Laura; Pistritto, Giuseppa; Cirone, Mara; D'Orazi, Gabriella

PML/RARa inhibits PTEN expression in hematopoietic cells by competing with PU.1 transcriptional activity

2016 - ONCOTARGET

Noguera, NÃ©lida InÃ©s; Piredda, Maria Liliana; Taulli, Riccardo; Catalano, Gianfranco; Angelini, Giulia; Gaur, Girish; Nervi, Clara; Voso, Maria Teresa; Lunardi, Andrea; Pandolfi, Pier Paolo; Lo Coco, Francesco

Age-related increase of thromboxane B2 and risk of cardiovascular disease in atrial fibrillation

2016 - ONCOTARGET

Pastori, Daniele; Pignatelli, Pasquale; Farcomeni, Alessio; Nocella, Cristina; Bartimoccia, Simona; Carnevale, Roberto; Violi, Francesco

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds.

2016 - ONCOTARGET

Carrella, D; Manni, I; Tumaini, B; Dattilo, R; Papaccio, Federica; Mutarelli, M; Sirci, F; Amoreo, Ca; Mottolese, Maurizio; Iezzi, Grazia Maria; Ciolli, Ludovico; Aria, V; Bosotti, R; Isacchi, A; Loreni, F; Bardelli, A; Avvedimento, Ve; DI BERNARDO, Diego; Cardone, L. 2.

IFN-Î± potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer

2016 - ONCOTARGET

Buoncervello, Maria; Romagnoli, Giulia; Buccarelli, Mariachiara; Fragale, Alessandra; Toschi, Elena; Parlato, Stefania; Lucchetti, Donatella; Macchia, Daniele; Spada, Massimo; Canini, Irene; Sanchez, Massimo; Falchi, Mario; Biffoni, Mauro; Belardelli, Filippo; Capone, Imerio; Sgambato, Alessandro; Vitiani, Lucia Ricci; Gabriele, Lucia; Musella, Martina

Nuclear Î²-arrestin1 is a critical cofactor of hypoxia-inducible factor-1Î± signaling in endothelin-1-induced ovarian tumor progression

2016 - ONCOTARGET

Cianfrocca, Roberta; Tocci, Piera; RosanÃ², Laura; Caprara, Valentina; Sestito, Rosanna; Di Castro, Valeriana; Bagnato, Anna

miR-30a inhibits endothelin A receptor and chemoresistance in ovarian carcinoma

2016 - ONCOTARGET

Sestito, Rosanna; Cianfrocca, Roberta; RosanÃ², Laura; Tocci, Piera; Semprucci, Elisa; Di Castro, Valeriana; Caprara, Valentina; Ferrandina, Gabriella; Sacconi, Andrea; Blandino, Giovanni; Bagnato, Anna

Low serum total testosterone level as a predictor of upstaging and upgrading in low-risk prostate cancer patients meeting the inclusion criteria for active surveillance

2016 - ONCOTARGET

Ferro, M; Lucarelli, G; Bruzzese, D; Di Lorenzo, G; PerdonÃ , S; Autorino, R; Cantiello, F; La Rocca, R; Busetto, GIAN MARIA; Cimmino, A; Buonerba, C; Battaglia, M; Damiano, R; De Cobelli, O; Mirone, V; Terracciano, D.

Identification of the zinc finger 216 (ZNF216) in human carcinoma cells. A potential regulator of EGFR activity

2016 - ONCOTARGET

Mincione, Gabriella; Di Marcantonio, Maria Carmela; Tarantelli, Chiara; Savino, Luca; Ponti, Donatella; Marchisio, Marco; Lanuti, Paola; Sancilio, Silvia; Calogero, Antonella; Di Pietro, Roberta; Muraro, Raffaella

Small heterodimer partner 1 directly interacts with NS5A viral protein and has a key role in HCV related liver cell transformation

2016 - ONCOTARGET

Conti, Beatrice; Porcu, Cristiana; Viscomi, Carmela; Minutolo, Antonella; Costantini, Susan; Corazzari, Marco; Iannucci, Gino; Barbaro, Barbara; Balsano, Clara