Pubblicazioni

Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2âEED Interaction

2021 - JOURNAL OF MEDICINAL CHEMISTRY

Du, Daohai; Xu, Dandan; Zhu, Licheng; Stazi, Giulia; Zwergel, Clemens; Liu, Yanli; Luo, Zhongyuan; Li, Yuanqing; Zhang, Yuanyuan; Zhu, Kongkai; Ding, Yiluan; Liu, Jingqiu; Fan, Shijie; Zhao, Kaiyan; Zhang, Naixia; Kong, Xiangqian; Jiang, Hualiang; Chen, Kaixian; Zhao, Kehao; Valente, Sergio; Min, Jinrong; Duan, Wenhu; Luo, Cheng

Downregulation of miR-326 and its host gene Î²-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth

2020 - MOLECULAR ONCOLOGY

Miele, Evelina; Po, Agnese; Mastronuzzi, Angela; Carai, Andrea; Besharat, Zein Mersini; Pediconi, Natalia; Abballe, Luana; Catanzaro, Giuseppina; Sabato, Claudia; De Smaele, Enrico; Canettieri, Gianluca; Di Marcotullio, Lucia; Vacca, Alessandra; Mai, Antonello; Levrero, Massimo; Pfister, Stefan M; Kool, Marcel; Giangaspero, Felice; Locatelli, Franco; Ferretti, Elisabetta

EZH2, JMJD3 and UTX epigenetically regulate hepatic plasticity inducing retro-differentiation and proliferation of liver cells

2019 - CELL DEATH & DISEASE

Pediconi, Natalia; Lupacchini, Leonardo; Salerno, Debora; Angrisani, Annapaola; Peruzzi, Giovanna; DE SMAELE, Enrico; Levrero, Massimo; Belloni, Laura

Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype

2019 - CLINICAL EPIGENETICS

Stazi, G.; Taglieri, L.; Nicolai, Alice; Romanelli, A.; Fioravanti, R.; Morrone, S.; Sabatino, M.; Ragno, R.; Taurone, S.; Nebbioso, M.; Carletti, R.; Artico, M.; Valente, S.; Scarpa, S.; Mai, A.

The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter

2018 - ONCOTARGET

Fazi, Barbara; Garbo, Sabrina; Toschi, Nicola; Mangiola, Annunziato; Lombari, Malinska; Sicari, Daria; Battistelli, Cecilia; Galardi, Silvia; Michienzi, Alessandro; Trevisi, Gianluca; Harari-Steinfeld, Rona; Cicchini, Carla; CiafrÃ¨, Silvia Anna

EZH2, HIF-1, and their inhibitors: An overview on pediatric cancers

2018 - FRONTIERS IN PEDIATRICS

Papale, Marco; Ferretti, Elisabetta; Battaglia, Giuseppe; Bellavia, Diana; Mai, Antonello; Tafani, Marco

Targeting of polycombs to DNA in EMT

2017 - ONCOTARGET

Battistelli, Cecilia; Tripodi, Marco; Cicchini, Carla

EZH2 and ZFX oncogenes in malignant behaviour of parathyroid neoplasms

2016 - ENDOCRINE

Sanpaolo, E.; Miroballo, M.; Corbetta, S.; Verdelli, C.; Baorda, F.; Balsamo, T.; Graziano, P.; Fabrizio, F. P.; Cinque, L.; Scillitani, A.; Muscarella, L. A.; Guarnieri, V.