Pubblicazioni

Human estrogen receptor α antagonists, part 2: Synthesis driven by rational design, in vitro antiproliferative, and in vivo anticancer evaluation of innovative coumarin-related antiestrogens as breast cancer suppressants

2022 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Kurtanovic, N.; Tomasevic, N.; Matic, S.; Mitrovic, M. M.; Kostic, D. A.; Sabatino, M.; Antonini, L.; Ragno, R.; Mladenovic, M.

Novel Insights on Human Carbonic Anhydrase Inhibitors Based on Coumalic Acid: Design, Synthesis, Molecular Modeling Investigation, and Biological Studies

2022 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Pontecorvi, Virginia; Mori, Mattia; Picarazzi, Francesca; Zara, Susi; Carradori, Simone; Cataldi, Amelia; Angeli, Andrea; Berrino, Emanuela; Chimenti, Paola; Ciogli, Alessia; Secci, Daniela; Guglielmi, Paolo; Supuran, Claudiu T.

New 1 H ‐indole‐2,3‐dione 3‐thiosemicarbazones with 3‐sulfamoylphenyl moiety as selective carbonic anhydrase inhibitors

2022 - ARCHIV DER PHARMAZIE
Eraslan‐elma, Pınar; Akdemir, Atilla; Berrino, Emanuela; Bozdağ, Murat; Supuran, Claudiu T.; Karalı, Nilgün

Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5

2022 - JOURNAL OF MEDICINAL CHEMISTRY
Fiorentino, F.; Castiello, C.; Mai, A.; Rotili, D.

An updated patent review on monoamine oxidase (MAO) inhibitors

2022 - EXPERT OPINION ON THERAPEUTIC PATENTS
Guglielmi, Paolo; Carradori, Simone; D'Agostino, Ilaria; Campestre, Cristina; Petzer, Jacobus P

New aspects of monoamine oxidase b inhibitors: The key role of halogens to open the golden door

2021 - CURRENT MEDICINAL CHEMISTRY
Mathew, B.; Carradori, S.; Guglielmi, P.; Uddin, M. D.; Kim, H.

Emerging Therapeutic Potential of SIRT6 Modulators

2021 - JOURNAL OF MEDICINAL CHEMISTRY
Fiorentino, F.; Mai, A.; Rotili, D.

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold

2019 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Rotondi, G.; Guglielmi, P.; Carradori, S.; Secci, D.; De Monte, C.; De Filippis, B.; Maccallini, C.; Amoroso, R.; Cirilli, R.; Akdemir, A.; Angeli, A.; Supuran, C. T.

Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis

2019 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Di Paolo, V.; Fulci, C.; Rotili, D.; Sciarretta, F.; Lucidi, A.; Morozzo della Rocca, B.; De Luca, A.; Rosato, A.; Quintieri, L.; Caccuri, A. M.

MAO inhibitors and their wider applications: a patent review

2018 - EXPERT OPINION ON THERAPEUTIC PATENTS
Carradori, Simone; Secci, Daniela; Petzer, Jacques P.

Efficient synthesis and first regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold and their evaluation in H2O2-induced oxidative stress

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Loubidi, Mohammed; Jouha, Jabrane; Tber, Zahira; Khouili, Mostafa; Suzenet, Franck; Akssira, Mohamed; Erdogan, Mümin Alper; Köse, Fadime Aydın; Dagcı, Taner; Armagan, Güliz; Saso, Luciano; Guillaumet, Gérald

9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-xanthene-3-one is a potentially novel antiplatelet drug which antagonizes the effect of thromboxane A2

2018 - MEDICINAL CHEMISTRY
Applová, Lenka; Veljović, Elma; Muratović, Samija; Karlíčková, Jana; Macáková, Kateřina; Završnik, Davorka; Saso, Luciano; Durić, Kemal; Mladĕnka, Přemysl

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Talapatra, Sandeep K.; Tham, Chuin Lean; Guglielmi, Paolo; Cirilli, Roberto; Chandrasekaran, Balakumar; Karpoormath, Rajshekhar; Carradori, Simone; Kozielski, Frank

Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes

2018 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Bua, Silvia; Berrino, Emanuela; Del Prete, Sonia; Murthy, Vallabhaneni S; Vijayakumar, Vijayaparthasarathi; Tamboli, Yasinalli; Capasso, Clemente; Cerbai, Elisabetta; Mugelli, Alessandro; Carta, Fabrizio; Supuran, Claudiu T

Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: evaluation of antimicrobial, cytotoxic and hemolytic activities

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Merlino, Francesco; Carotenuto, Alfonso; Casciaro, Bruno; Martora, Francesca; Loffredo, MARIA ROSA; DI GRAZIA, Antonio; Yousif, Ali M.; Brancaccio, Diego; Palomba, Luciana; Novellino, Ettore; Galdiero, Massimiliano; Iovene, Maria Rosaria; Mangoni, Maria Luisa; Grieco, Paolo

Natural modulators of nonalcoholic fatty liver disease: mode of action analysis and in silico ADME-Tox prediction

2017 - TOXICOLOGY AND APPLIED PHARMACOLOGY
Al Sharif, Merilin; Alov, Petko; Vitcheva, Vessela; Diukendjieva, Antonia; Mori, Mattia; Botta, Bruno; Tsakovska, Ivanka; Pajeva, Ilza

Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

2016 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Matera, Carlo; Quadri, Marta; Sciaccaluga, Miriam; Pomè, Diego Yuri; Fasoli, Francesca; De Amici, Marco; Fucile, Sergio; Gotti, Cecilia; Dallanoce, Clelia; Grazioso, Giovanni

Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions

2016 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Drinkwater, Nyssa; Vinh, Natalie B.; Mistry, Shailesh N.; Bamert, Rebecca S.; Ruggeri, Chiara; Holleran, John P.; Loganathan, Sasdekumar; Paiardini, Alessandro; Charman, Susan A.; Powell, Andrew K.; Avery, Vicky M.; Mcgowan, Sheena; Scammells, Peter J.

Inhibition of human monoamine oxidase: biological and molecular modeling studies on selected natural flavonoids

2016 - JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Carradori, Simone; Gidaro, Maria Concetta; Petzer, Anél; Costa, Giosuè; Guglielmi, Paolo; Chimenti, Paola; Alcaro, Stefano; Petzer, Jacobus P.

Recreational use, analysis and toxicity of tryptamines

2015 - CURRENT NEUROPHARMACOLOGY
Tittarelli, Roberta; Mannocchi, Giulio; Pantano, Flaminia; Romolo, Francesco Saverio

Enzyme kinetics and inhibition of histone acetyltransferase KAT8

2015 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Wapenaar, Hannah; van der Wouden, Petra E; Groves, Matthew R; Rotili, Dante; Mai, Antonello; Dekker, Frank J.

Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF

2015 - CHEMMEDCHEM
Castellano, Sabrina; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Mai, Antonello; Novellino, Ettore; Tosco, Alessandra; Sbardella, Gianluca

Green-synthesized silver nanoparticles as a novel control tool against dengue virus (DEN-2) and its primary vector Aedes aegypti

2015 - PARASITOLOGY RESEARCH
Sujitha, Vasu; Murugan, Kadarkarai; Paulpandi, Manickam; Panneerselvam, Chellasamy; Suresh, Udaiyan; Roni, Mathath; Nicoletti, Marcello; Higuchi, Akon; Madhiyazhagan, Pari; Subramaniam, Jayapal; Dinesh, Devakumar; Vadivalagan, Chithravel; Chandramohan, Balamurugan; Alarfaj, Abdullah A.; Munusamy, Murugan A.; Barnard, Donald R.; Benelli, Giovanni

Chemistry and pharmacology of a series of unichiral analogues of 2-(2-pyrrolidinyl)-1,4-benzodioxane, prolinol phenyl ether, and prolinol 3-pyridyl ether designed as α4β2-nicotinic acetylcholine receptor agonists

2015 - JOURNAL OF MEDICINAL CHEMISTRY
Bolchi, Cristiano; Valoti, Ermanno; Gotti, Cecilia; Fasoli, Francesca; Ruggeri, Paola; Fumagalli, Laura; Binda, Matteo; Mucchietto, Vanessa; Sciaccaluga, Miriam; Budriesi, Roberta; Fucile, Sergio; Pallavicini, Marco

Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors

2015 - BIOORGANIC & MEDICINAL CHEMISTRY
Consalvi, Sara; Alfonso, Salvatore; Di Capua, Angela; Poce, Giovanna; Pirolli, Adele; Sabatino, Manuela; Ragno, Rino; Anzini, Maurizio; Sartini, Stefania; La Motta, Concettina; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Biava, Mariangela

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