Pubblicazioni

Analysis of Punicalin and Punicalagin Interaction with PDIA3 and PDIA1

2024 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Meschiari, Giorgia; Minacori, Marco; Fiorini, Sara; Tedesco, Mariassunta; Eufemi, Margherita; Altieri, Fabio

Protein Disulfide Isomerase A3 (PDIA3): A Pharmacological Target in Glioblastoma?

2023 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Paglia, Giuliano; Minacori, Marco; Meschiari, Giorgia; Fiorini, Sara; Chichiarelli, Silvia; Eufemi, Margherita; Altieri, Fabio

Stabilization of the Dimeric State of SARS-CoV-2 Main Protease by GC376 and Nirmatrelvir

2023 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Paciaroni, A.; Libera, V.; Ripanti, F.; Orecchini, A.; Petrillo, C.; Francisci, D.; Schiaroli, E.; Sabbatini, S.; Gidari, A.; Bianconi, E.; Macchiarulo, A.; Hussain, R.; Silvestrini, L.; Moretti, P.; Belhaj, N.; Vercelli, M.; Roque, Y.; Mariani, P.; Comez, L.; Spinozzi, F.

Effects of 26âweeks of treatment with empagliflozin versus glimepiride on the myocardial glucose metabolic rate in patients with type 2 diabetes: The randomized, open-label, crossover, active-comparator FIORE trial

2022 - DIABETES, OBESITY AND METABOLISM

Succurro, Elena; Vizza, Patrizia; Papa, Annalisa; Miceli, Sofia; Cicone, Francesco; Fiorentino, Teresa Vanessa; Sciacqua, Angela; Andreozzi, Francesco; Veltri, Pierangelo; Cascini, Giuseppe Lucio; Sesti, Giorgio

Emerging Direct Targeting Î²-Catenin Agents

2022 - MOLECULES

Nalli, M.; Masci, D.; Urbani, A.; La Regina, G.; Silvestri, R.

A comparative analysis of punicalagin interaction with PDIA1 and PDIA3 by biochemical and computational approaches

2021 - BIOMEDICINES

Paglia, G.; Antonini, L.; Cervoni, L.; Ragno, R.; Sabatino, M.; Minacori, M.; Rubini, E.; Altieri, F.

Discovery of new 1,1'-biphenyl-4-sulfonamides as selective subnanomolar human carbonic anhydrase II inhibitors

2020 - ACS MEDICINAL CHEMISTRY LETTERS

La Regina, G.; Puxeddu, M.; Nalli, M.; Vullo, D.; Gratteri, P.; Supuran, C. T.; Nocentini, A.; Silvestri, R.

Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies

2020 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Puxeddu, M.; Shen, H.; Bai, R.; Coluccia, A.; Nalli, M.; Mazzoccoli, C.; Da Pozzo, E.; Cavallini, C.; Martini, C.; Orlando, V.; Biagioni, S.; Mazzoni, C.; Coluccia, A. M. L.; Hamel, E.; Liu, T.; Silvestri, R.; La Regina, G.

Reduced lysosomal acid lipase activity in blood and platelets is associated with nonalcoholic fatty liver disease

2020 - CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY

Ferri, Flaminia; Mischitelli, Monica; Tozzi, Giulia; Messina, Emanuele; Mignini, Irene; Mazzuca, Sergio; Pellone, Monica; Parisse, Simona; Marrapodi, Ramona; Visentini, Marcella; Baratta, Francesco; Del Ben, Maria; Pastori, Daniele; Perciballi, Roberta; Attilia, Maria Luisa; Carbone, Martina; De Santis, Adriano; Violi, Francesco; Angelico, Francesco; Ginanni Corradini, Stefano

Alvaxanthone, a thymidylate synthase inhibitor with nematocidal and tumoricidal activities

2020 - MOLECULES

Maj, P.; Mori, M.; Sobich, J.; Markowicz, J.; Uram, L.; Zielinski, Z.; Quaglio, D.; Calcaterra, A.; Cau, Y.; Botta, B.; Rode, W.

Azidothymidine "clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors

2020 - JOURNAL OF MEDICINAL CHEMISTRY

Berrino, E.; Angeli, A.; Zhdanov, D. D.; Kiryukhina, A. P.; Milaneschi, A.; De Luca, A.; Bozdag, M.; Carradori, S.; Selleri, S.; Bartolucci, G.; Peat, T. S.; Ferraroni, M.; Supuran, C. T.; Carta, F.

Screening pyridine derivatives against human hydrogen sulfide-synthesizing enzymes by orthogonal methods

2019 - SCIENTIFIC REPORTS

Zuhra, Karim; Sousa, Pedro M F; Paulini, Giulia; Lemos, Ana Rita; Kalme, Zenta; Bisenieks, Imants; Bisenieks, Egils; Vigante, Brigita; Duburs, Gunars; Bandeiras, Tiago M; Saso, Luciano; GiuffrÃ¨, Alessandro; Vicente, JoÃ£o B

4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis

2019 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Secci, Daniela; Carradori, Simone; Petzer, AnÃ©l; Guglielmi, Paolo; DâAscenzio, Melissa; Chimenti, Paola; Bagetta, Donatella; Alcaro, Stefano; Zengin, Gokhan; Petzer, Jacobus P.; Ortuso, Francesco

Synthesis and carbonic anhydrase inhibitory properties of novel 4-(2-aminoethyl)benzenesulfonamide-dipeptide conjugates

2019 - BIOORGANIC CHEMISTRY

KÃ¼Ã§Ã¼kbay, Hasan; BuÄday, Nesrin; KÃ¼Ã§Ã¼kbay, F. Zehra; Berrino, Emanuela; Bartolucci, Gian Luca; Del Prete, Sonia; Capasso, Clemente; Supuran, Claudiu T.

What's new in the treatment of atopic dermatitis

2019 - DERMATOLOGIC THERAPY

Dattola, A; Bennardo, L; Silvestri, M; Nistico', S

Correction to: The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma

2018 - JOURNAL OF HEMATOLOGY & ONCOLOGY

Festuccia, C; Mancini, A; Colapietro, A; Gravina, G L; Vitale, F; Marampon, F; Delle Monache, S; Pompili, S; Cristiano, L; Vetuschi, A; Tombolini, V; Chen, Y; Mehrling, T

The relevance of Ki calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor.

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Wapenaar, H; van den Bosch, T; Leus, Ngj; van der Wouden, Pe; Eleftheriadis, N; Hermans, J; Hailu, Gs; Rotili, D; Mai, A; DÃ¶mling, A; Bischoff, R; Haisma, Hj; Dekker, F. J.

Histone demethylating agents as potential S-adenosyl-l-methionine-competitors

2016 - MEDCHEMCOMM

NavakauskienÄ, R.; Mori, Mattia; Christodoulou, M. S.; ZentelytÄ, A.; Botta, Bruno; Via, L. Dalla; Ricci, F.; Damia, G.; Passarella, D.; Zilio, C.; Martinet, N.

Inhibition of Alzheimer's BACE-1 by 2,6-dialkyl-4-chromon-3-yl-1,4-dihydropyridine-3,5-dicarboxylates

2015 - MEDICINAL CHEMISTRY RESEARCH

Razzaghi-Asl, N.; Aggarwal, N.; Srivastava, S.; Parmar, V. S.; Prasad, A. K.; Miri, R.; Saso, L.; Firuzi, O.