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Studio prospettico sulla chirurgia bariatrica di revisione per recupero del peso e reflusso gastro-esofageo: confronto tra Bypass Duodeno-Ileale associato a Sleeve Gastrectomy (SADI-S) e Roux-en-Y By-pass gastrico per via laparoscopica |
Alessandro Maria Paganini |
bariatric surgery, weight regain, Gastroesophageal reflux disease |
Scopo del presente studio prospettico osservazionale è di valutare, in pazienti con weight regain e/o MRGE dopo chirurgia bariatrica primaria, l'outcome dopo re-intervento di SADI-S e confrontarlo con i pazienti sottoposti a re-intervento di RYBG |
DIPARTIMENTO DI CHIRURGIA GENERALE E SPECIALISTICA "PARIDE STEFANINI" |
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Routine near infra‑red indocyanine green fluorescent cholangiography versus intraoperative cholangiography during laparoscopic cholecystectomy |
Alessandro Maria Paganini |
laparoscopic cholecystectomy, Intraoperative cholangiography (IOC), Near infrared (NIR) fluorescence, Indocyanine green (ICG) |
The authors evaluate safety and efficacy of near infra-red ICG fluorescence imaging during laparoscopic cholecystectomy (LC) and compare perioperative data with a series of patients who underwent LC with routine traditional intraoperative cholangiography |
DIPARTIMENTO DI CHIRURGIA GENERALE E SPECIALISTICA "PARIDE STEFANINI" |
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Esofagectomia sec. McKeown mininvasiva versus ibrida per cancro: risultati perioperatori. |
Alessandro Maria Paganini |
Esophageal cancer, mini invasive esophagectomy |
L’esofagectomia totalmente mininvasiva (TMIE) per il trattamento del cancro dell’esofago viene eseguita più di frequente, tuttavia la sua superiorità rispetto all’esofagectomia ibrida mininvasiva e open (HMIE) non è ancora accertata. |
DIPARTIMENTO DI CHIRURGIA GENERALE E SPECIALISTICA "PARIDE STEFANINI" |
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Results after laparoscopic left anterior transperitoneal submesocolic adrenalectomy for the treatment of adrenal benign and malignant disease |
Alessandro Maria Paganini |
Laparoscopic transperitoneal anterior adrenalectomy, Laparoscopic transperitoneal anterior submesocolic left adrenalectomy, Adrenal lesions, Adrenal pheochromocytoma |
The aim of this study is to evaluate the feasibility, safety, advantages and surgical outcomes of laparoscopic adrenalectomy by an anterior transperitoneal approach in benign and malignant disease |
DIPARTIMENTO DI CHIRURGIA GENERALE E SPECIALISTICA "PARIDE STEFANINI" |
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Indocyanine Green Fluorescence Angiography During Laparoscopic Bariatric Surgery |
Alessandro Maria Paganini |
indocyanine green fluorescence angiography, laparoscopic sleeve gastrectomy (LSG), bypass surgery, bariatric surgery, anastomotic leakage |
ICG-fluorescence angiography is used for several purposes in general surgery, but in bariatric surgery is debated. The objective of this study is to evaluate the intraoperative use of ICG-FA during bariatric surgery to reduce the postoperative leak rate. |
DIPARTIMENTO DI CHIRURGIA GENERALE E SPECIALISTICA "PARIDE STEFANINI" |
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Does Sleeve Gastrectomy Worsen Gastroesophageal Reflux Disease in Obese Patients? A Prospective Study |
Alessandro Maria Paganini |
gastroesophageal reflux disease (GERD), laparoscopic sleeve gastrectomy (LSG), gastric bypass, High-resolution manometry, pHmanometry, 24h-pH-impedance, bariatric surgery |
To evaluate the impact of laparoscopic sleeve gastrectomy (LSG) and gastric bypass (LGB) on gastroesophageal reflux disease (GERD). |
DIPARTIMENTO DI CHIRURGIA GENERALE E SPECIALISTICA "PARIDE STEFANINI" |
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Does Sleeve Gastrectomy Worsen Gastroesophageal Reflux Disease in Obese Patients? A Prospective Study |
Alessandro Maria Paganini |
gastroesophageal reflux disease (GERD), laparoscopic sleeve gastrectomy (LSG), gastric bypass, High-resolution manometry, pHmanometry, 24h-pH-impedance, bariatric surgery |
To evaluate the impact of laparoscopic sleeve gastrectomy (LSG) and gastric bypass (LGB) on gastroesophageal reflux disease (GERD). |
DIPARTIMENTO DI CHIRURGIA GENERALE E SPECIALISTICA "PARIDE STEFANINI" |
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Circadian Regulation of Immune cells |
Mary Anna Venneri |
clock genes, Circadian Clocks, circadian rhythms, circadian gene, peripheral blood mononuclear cells (PBMCs), NK cell, monocytes, monocyte subsets |
The group study the role of the circadian clock to coordinate functions of the immune system both at steady-state and in response to glucocorticoids excess |
DIPARTIMENTO DI MEDICINA SPERIMENTALE |
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Botta Lab |
Bruno Botta |
natural product chemistry, macrocycles, Bioconjugates, Anticancer drugs, antibacterial agents |
L’ambito scientifico della ricerca che caratterizza il “Botta lab” è quello della chimica organica, con particolare attenzione per la chimica dei macrocicli e dei composti naturali. |
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO |
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Adipose tissue remodeling |
Mary Anna Venneri |
diabetes and metabolism, diabetes complications, adipose tissue inflammation, adipocyte differentiation, Adipose tissue dysfunction, genetic mouse models, C57 wild-type (WT) mice, M2 polarized macrophage, browning, angiogenic mediators, Thermogenesis |
In vitro and in vivo induced models to identify innovative drug/therapy target molecules involved in adipose tissue remodeling |
DIPARTIMENTO DI MEDICINA SPERIMENTALE |
