Pubblicazioni

SAHA/5-AZA Enhances Acetylation and Degradation of mutp53, Upregulates p21 and Downregulates c-Myc and BRCA-1 in Pancreatic Cancer Cells

2024 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Di Crosta, Michele; Ragone, Francesca Chiara; Benedetti, Rossella; D'Orazi, Gabriella; Gilardini Montani, Maria Saveria; Cirone, Mara

Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells

2023 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Negri, Aide; Marozzi, Marina; Trisciuoglio, Daniela; Rotili, Dante; Mai, Antonello; Rizzi, Federica

Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent

2023 - ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE
Nalli, Marianna; Di Magno, Laura; Wen, Yichao; Liu, Xin; D’Ambrosio, Michele; Puxeddu, Michela; Parisi, Anastasia; Sebastiani, Jessica; Sorato, Andrea; Coluccia, Antonio; Ripa, Silvia; Di Pastena, Fiorella; Capelli, Davide; Montanari, Roberta; Masci, Domiziana; Urbani, Andrea; Naro, Chiara; Sette, Claudio; Orlando, Viviana; D’Angelo, Sara; Biagioni, Stefano; Bigogno, Chiara; Dondio, Giulio; Pastore, Arianna; Stornaiuolo, Mariano; Canettieri, Gianluca; Liu, Te; Silvestri, Romano; La Regina, Giuseppe

NFE2L2 and STAT3 Converge on Common Targets to Promote Survival of Primary Lymphoma Cells

2023 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Arena, Andrea; DI CROSTA, Michele; Gonnella, Roberta; Zarrella, Roberta; Romeo, Maria Anele; Benedetti, Rossella; GILARDINI MONTANI, MARIA SAVERIA; Santarelli, Roberta; D’Orazi, Gabriella; Cirone, Mara

JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanisms

2023 - EXPERIMENTAL HEMATOLOGY
Arena, Andrea; Romeo, Maria Anele; Benedetti, Rossella; Gilardini Montani, Maria Saveria; Cirone, Mara

DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication

2022 - BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Arena, A.; Gilardini Montani, M. S.; Romeo, M. A.; Benedetti, R.; Gaeta, A.; Cirone, M.

Targeting an MDM2/MYC Axis to Overcome Drug Resistance in Multiple Myeloma

2022 - CANCERS
Faruq, Omar; Zhao, Davidson; Shrestha, Mariusz; Vecchione, Andrea; Zacksenhaus, Eldad; Chang, Hong

Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells

2022 - BIOMEDICINES
Arena, A.; Romeo, M. A.; Benedetti, R.; Gilardini Montani, M. S.; Cirone, M.

c-MYC Protein Stability Is Sustained by MAPKs in Colorectal Cancer

2022 - CANCERS
Lepore Signorile, Martina; Grossi, Valentina; Fasano, Candida; Forte, Giovanna; Disciglio, Vittoria; Sanese, Paola; De Marco, Katia; La Rocca, Francesca; Armentano, Raffaele; Valentini, Anna Maria; Giannelli, Gianluigi; Simone, Cristiano

METTL3-dependent MALAT1 delocalization drives c-Myc induction in thymic epithelial tumors

2021 - CLINICAL EPIGENETICS
Iaiza, A.; Tito, C.; Ianniello, Z.; Ganci, F.; Laquintana, V.; Gallo, E.; Sacconi, A.; Masciarelli, S.; De Angelis, L.; Aversa, S.; Diso, D.; Anile, M.; Petrozza, V.; Facciolo, F.; Melis, E.; Pescarmona, E.; Venuta, F.; Marino, M.; Blandino, G.; Fontemaggi, G.; Fatica, A.; Fazi, F.

Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in multiple myeloma

2020 - BLOOD ADVANCES
Ricciardi, Maria Rosaria; Petrucci, Maria Teresa; Pierluigi Spugnini, Enrico; Baldi, Alfonso; Cioce, Mario; Cortese, Giancarlo; Mattei, Elisabetta; Merola, Roberta; Gianelli, Umberto; Baldini, Luca; Pisani, Francesco; Gumenyuk, Svitlana; Mengarelli, Andrea; Höpker, Katja; Benzing, Thomas; Vincenzi, Bruno; Floridi, Aristide; Passananti, Claudio; Blandino, Giovanni; Iezzi, Simona; Fanciulli, Maurizio

Disruption of MEK/ERK/c-Myc signaling radiosensitizes prostate cancer cells in vitro and in vivo

2018 - JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
Ciccarelli, Carmela; Di Rocco, Agnese; Gravina, Giovanni Luca; Mauro, Annunziata; Festuccia, Claudio; Del Fattore, Andrea; Berardinelli, Paolo; De Felice, Francesca; Musio, Daniela; Bouché, Marina; Tombolini, Vincenzo; Zani, Bianca Maria; Marampon, Francesco

Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt's lymphoma

2016 - THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Granato, Marisa; Rizzello, Celeste; Romeo, Maria Anele; Yadav, Shivangi; Santarelli, Roberta; D'Orazi, Gabriella; Faggioni, Alberto; Cirone, Mara

C-MYC modulation induces responsiveness to paclitaxel in adrenocortical cancer cell lines

2015 - INTERNATIONAL JOURNAL OF ONCOLOGY
Cerquetti, Lidia; Sampaoli, Camilla; De Salvo, M; Bucci, B; Argese, N; Chimento, A; Vottari, S; Marchese, R; Pezzi, V; Toscano, Vincenzo; Stigliano, Antonio

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