Pubblicazioni

SAR Analysis of Novel Coxsackie virus A9 Capsid Binders

2024 - JOURNAL OF MEDICINAL CHEMISTRY

Tammaro, Chiara; Plavec, Zlatka; MyllymÃ¤ki, Laura; Mitchell, Cristopher; Consalvi, Sara; Biava, Mariangela; Ciogli, Alessia; Domanska, AuÅ¡ra; Leppilampi, Valtteri; Buckner, Cienna; Manetto, Simone; SciÃ², Pietro; Coluccia, Antonio; Laajala, Mira; Dondio, Giulio M; Bigogno, Chiara; MarjomÃ¤ki, Varpu; Butcher, Sarah J; Poce, Giovanna

5-Oxohexahydroquinolines bearing 4-pyridyl methyl carboxylate as P-glycoprotein inhibitors and multidrug resistance reversal agents in cancer cells

2023 - JOURNAL OF MOLECULAR STRUCTURE

Ranjbar, Sara; Faramin Lashkarian, Faramak; Khoshneviszadeh, Mehdi; Moosavi, Fatemeh; Sakhteman, Amirhossein; Zargari, Farshid; Saso, Luciano; Firuzi, Omidreza; Edraki, Najmeh

Novel spiroindoline quinazolinedione derivatives as anticancer agents and potential FLT3 kinase inhibitors

2023 - BIOORGANIC & MEDICINAL CHEMISTRY

Divar, Masoumeh; Edraki, Najmeh; Damghani, Tahereh; Moosavi, Fatemeh; Mohabbati, Maryam; Alipour, Alireza; Pirhadi, Somayeh; Saso, Luciano; Khabnadideh, Soghra; Firuzi, Omidreza

Human estrogen receptor Î± antagonists, part 2: Synthesis driven by rational design, in vitro antiproliferative, and in vivo anticancer evaluation of innovative coumarin-related antiestrogens as breast cancer suppressants

2022 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Kurtanovic, N.; Tomasevic, N.; Matic, S.; Mitrovic, M. M.; Kostic, D. A.; Sabatino, M.; Antonini, L.; Ragno, R.; Mladenovic, M.

Small-molecule inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H function. Challenges and recent developments

2021 - CURRENT MEDICINAL CHEMISTRY

Madia, Valentina Noemi; Messore, Antonella; De Leo, Alessandro; Tudino, Valeria; Pindinello, Ivano; Saccoliti, Francesco; De Vita, Daniela; Scipione, Luigi; Costi, Roberta; Di Santo, Roberto

Embelin as lead compound for new neuroserpin polymerization inhibitors

2020 - LIFE

Visentin, C.; Musso, L.; Broggini, L.; Bonato, F.; Russo, R.; Moriconi, C.; Bolognesi, M.; Miranda, E.; Dallavalle, S.; Passarella, D.; Ricagno, S.

Drug design and synthesis of first in class PDZ1 targeting NHERF1 inhibitors as anticancer agents

2019 - ACS MEDICINAL CHEMISTRY LETTERS

Coluccia, A.; La Regina, G.; Naccarato, V.; Nalli, M.; Orlando, V.; Biagioni, S.; De Angelis, M. L.; Baiocchi, M.; Gautier, C.; Gianni, S.; Di Pastena, F.; Di Magno, L.; Canettieri, G.; Coluccia, A. M. L.; Silvestri, R.

5-Oxo-hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters to overcome multidrug resistance in cancer cells

2019 - TOXICOLOGY AND APPLIED PHARMACOLOGY

Ranjbar, S.; Khonkarn, R.; Moreno, A.; Baubichon-Cortay, H; Miri, R.; Khoshneviszadeh, M.; Saso, L.; Edraki, N.; Falson, P.; Firuzi, O.

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold

2019 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Rotondi, G.; Guglielmi, P.; Carradori, S.; Secci, D.; De Monte, C.; De Filippis, B.; Maccallini, C.; Amoroso, R.; Cirilli, R.; Akdemir, A.; Angeli, A.; Supuran, C. T.

MAO inhibitors and their wider applications: a patent review

2018 - EXPERT OPINION ON THERAPEUTIC PATENTS

Carradori, Simone; Secci, Daniela; Petzer, Jacques P.

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Talapatra, Sandeep K.; Tham, Chuin Lean; Guglielmi, Paolo; Cirilli, Roberto; Chandrasekaran, Balakumar; Karpoormath, Rajshekhar; Carradori, Simone; Kozielski, Frank

The pharmacological management of NAFLD in children and adolescents

2017 - EXPERT REVIEW OF CLINICAL PHARMACOLOGY

Liyanagedera, S; Williams, Rp; Veraldi, S; Nobili, V; Mann, Jp.

A comparative study of warheads for design of cysteine protease inhibitors

2017 - BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Silva, Daniel G; Ribeiro, Jean F R; De Vita, Daniela; Cianni, Lorenzo; Franco, Caio Haddad; Freitas-Junior, Lucio H; Moraes, Carolina Borsoi; Rocha, Josmar R; Burtoloso, Antonio C B; Kenny, Peter W; LeitÃ£o, Andrei; Montanari, Carlos A

Targeting endothelin-1 receptor/ÃÂ²-arrestin1 network for the treatment of ovarian cancer

2017 - EXPERT OPINION ON THERAPEUTIC TARGETS

RosanÃ£Â², Laura; Cianfrocca, Roberta; Sestito, Rosanna; Tocci, Piera; Di Castro, Valeriana; Bagnato, Anna

Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes

2017 - BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Musumeci, Domenica; Amato, Jussara; Zizza, Pasquale; Platella, Chiara; Cosconati, Sandro; Cingolani, Chiara; Biroccio, Annamaria; Novellino, Ettore; Randazzo, Antonio; Giancola, Concetta; Pagano, Bruno; Montesarchio, Daniela

Molecular medicine - to be or not to be

2016 - BIOPHYSICAL CHEMISTRY

Brunori, Maurizio; Gianni, Stefano

Epigenetics in medullary thyroid cancer: from pathogenesis to targeted therapy

2016 - RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY

Vitale, Giovanni; Dicitore, Alessandra; Messina, Erika; Sciammarella, Concetta; Faggiano, Antongiulio; Colao, Annamaria

Tecnologie Farmaceutiche - Progettazione e allestimento dei medicinali

2015 - Tecnologie Farmaceutiche, Progettazione e allestimento dei medicinali

Coviello, Tommasina

Discovery of 1,1'-biiphenyl-4-sulfonamides as a new class of potent and selective carbonic anhydrase XIV inhibitors

2015 - JOURNAL OF MEDICINAL CHEMISTRY

LA REGINA, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; Pelliccia, Sveva; Monti, Ludovica; Vullo, Daniela; Nuti, Elisa; Alterio, Vincenzo; De Simone, Giuseppina; Monti, Simona Maria; Pan, Peiwen; Parkkila, Seppo; Supuran, Claudiu T.; Rossello, Armando; Silvestri, Romano

Emerging approaches for histone deacetylase inhibitor drug discovery

2015 - EXPERT OPINION ON DRUG DISCOVERY

Zwergel, Clemens; Valente, Sergio; Jacob, Claus; Mai, Antonello

Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors

2015 - BIOORGANIC & MEDICINAL CHEMISTRY

Consalvi, Sara; Alfonso, Salvatore; Di Capua, Angela; Poce, Giovanna; Pirolli, Adele; Sabatino, Manuela; Ragno, Rino; Anzini, Maurizio; Sartini, Stefania; La Motta, Concettina; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Biava, Mariangela

An overview of early investigational therapies for chemoresistant ovarian cancer

2015 - EXPERT OPINION ON INVESTIGATIONAL DRUGS

Marchetti, Claudia; Ledermann, Jonathan A.; BENEDETTI PANICI, Pierluigi