Pubblicazioni

Nutrient restriction-activated Fra-2 promotes tumor progression via IGF1R in miR-15a downmodulated pancreatic ductal adenocarcinoma

2024 - SIGNAL TRANSDUCTION AND TARGETED THERAPY

Rampioni Vinciguerra, Gian Luca; Capece, Marina; Reggiani Bonetti, Luca; Nigita, Giovanni; Calore, Federica; Rentsch, Sydney; Magistri, Paolo; Ballarin, Roberto; Di Benedetto, Fabrizio; Distefano, Rosario; Cirombella, Roberto; Vecchione, Andrea; Belletti, Barbara; Baldassarre, Gustavo; Lovat, Francesca; Croce, Carlo M.

Autophagy Activation Associates with Suppression of Prion protein and Improved Mitochondrial Status in Glioblastoma Cells

2023 - CELLS

Lenzi, Paola; Busceti, Carla; Lazzeri, Gloria; Ferese, Rosangela; Biagioni, Francesca; Salvetti, Alessandra; Pompili, Elena; DE FRANCHIS, Valerio; Puglisi-Allegra, Stefano; Frati, Alessandro; Ferrucci, Michela; Fornai, Francesco

The Exosome-Mediated PI3K/Akt/mTOR Signaling Pathway in Neurological Diseases

2023 - PHARMACEUTICS

Iranpanah, Amin; Kooshki, Leila; Zachariah Moradi, Seyed; Saso, Luciano; Fakhri, Sajad; Khan, Haroon

SMYD3 Modulates AMPK-mTOR Signaling Balance in Cancer Cell Response to DNA Damage

2023 - CELLS

Lepore Signorile, Martina; Sanese, Paola; Di Nicola, Elisabetta; Fasano, Candida; Forte, Giovanna; De Marco, Katia; Disciglio, Vittoria; Latrofa, Marialaura; Pantaleo, Antonino; Varchi, Greta; Del Rio, Alberto; Grossi, Valentina; Simone, Cristiano

3,4-Dihydroxyphenylethanol (DPE or Hydroxytyrosol) Counteracts ERK1/2 and mTOR Activation, Pro-Inflammatory Cytokine Release, Autophagy and Mitophagy Reduction Mediated by Benzo[a]pyrene in Primary Human Colonic Epithelial Cells

2022 - PHARMACEUTICS

Santarelli, R.; Pompili, C.; Gilardini Montani, M. S.; Evangelista, L.; Gonnella, R.; Cirone, M.

NRF2 in Cancer: Cross-Talk with Oncogenic Pathways and Involvement in Gammaherpesvirus-Driven Carcinogenesis

2022 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cirone, Mara; D'Orazi, Gabriella

The complex network of mTOR signalling in the heart

2022 - CARDIOVASCULAR RESEARCH

Sciarretta, S.; Forte, M.; Frati, G.; Sadoshima, J.

Treatment with the bacterial toxin CNF1 selectively rescues cognitive and brain mitochondrial deficits in a female mouse model of Rett syndrome carrying a MeCP2-null mutation

2021 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Urbinati, C.; Cosentino, L.; Germinario, E. A. P.; Valenti, D.; Vigli, D.; Ricceri, L.; Laviola, G.; Fiorentini, C.; Vacca, R. A.; Fabbri, A.; De Filippis, B.

Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles

2021 - ALZHEIMER'S & DEMENTIA

Perluigi, M.; Picca, A.; Montanari, E.; Calvani, R.; Marini, F.; Matassa, R.; Tramutola, A.; Villani, A.; Familiari, G.; Domenico, F. D.; Butterfield, D. A.; Oh, K. J.; Marzetti, E.; Valentini, D.; Barone, E.

Autophagy and the lysosomal system in cancer

2021 - CELLS

Kumar, Suresh; SÃ¡nchez-Ãlvarez, Miguel; Lolo, Fidel-NicolÃ¡s; Trionfetti, Flavia; Strippoli, Raffaele; Marco, Cordani

mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder

2021 - FREE RADICAL BIOLOGY & MEDICINE

Perluigi, M.; Di Domenico, F.; Barone, E.; Butterfield, D. A.

Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties

2021 - CELL DEATH & DISEASE

Luca, R.; Assenza, M. R.; Maiullari, F.; Pieroni, L.; Maiullari, S.; Federici, G.; Marini, F.; Rizzi, R.; Urbani, A.; Soddu, S.; Moretti, F.

Oxidative stress and mTOR in Down syndrome brain: Link to Alzheimerâs dysmetabolism, neuropathology, and possible therapies

2021 - FREE RADICAL BIOLOGY & MEDICINE

Perluigi, M.; Di Domenico, F.; Butterfield, D. A.

Upfront treatment with mTOR inhibitor everolimus in pediatric low-grade gliomas: A single-center experience

2021 - INTERNATIONAL JOURNAL OF CANCER

Cacchione, Antonella; Lodi, Mariachiara; Carai, Andrea; Miele, Evelina; Tartaglia, Marco; Megaro, Giacomina; Del Baldo, Giada; Alessi, Iside; Colafati, Giovanna Stefania; Carboni, Alessia; Boccuto, Luigi; Diomedi Camassei, Francesca; Catanzaro, Giuseppina; Po, Agnese; Ferretti, Elisabetta; Pedace, Lucia; Pizzi, Simone; Folgiero, Valentina; Pezzullo, Marco; Corsetti, Tiziana; Secco, Domitilla Elena; Cefalo, Maria Giuseppina; Locatelli, Franco; Mastronuzzi, Angela

BVR-A deficiency leads to autophagy impairment through the dysregulation of AMPK/mTOR axis in the brainâImplications for neurodegeneration

2020 - ANTIOXIDANTS

Lanzillotta, C.; Zuliani, I.; Vasavda, C.; Snyder, S.; Paul, B.; Perluigi, M.; Di Domenico, F.; Barone, E.

mTOR regulation of metabolism in hematologic malignancies

2020 - CELLS

Mirabilii, Simone; Ricciardi, Maria Rosaria; Tafuri, Agostino

Inhibition of phosphoinositide 3-kinase/protein kinase B signaling hampers the vasopressin-dependent stimulation of myogenic differentiation

2019 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sorrentino, S.; Barbiera, A.; Proietti, G.; Sica, G.; Adamo, S.; Scicchitano, B. M.

Ricerc@Sapienza

Pubblicazioni

Nutrient restriction-activated Fra-2 promotes tumor progression via IGF1R in miR-15a downmodulated pancreatic ductal adenocarcinoma

Autophagy Activation Associates with Suppression of Prion protein and Improved Mitochondrial Status in Glioblastoma Cells

The Exosome-Mediated PI3K/Akt/mTOR Signaling Pathway in Neurological Diseases

SMYD3 Modulates AMPK-mTOR Signaling Balance in Cancer Cell Response to DNA Damage

3,4-Dihydroxyphenylethanol (DPE or Hydroxytyrosol) Counteracts ERK1/2 and mTOR Activation, Pro-Inflammatory Cytokine Release, Autophagy and Mitophagy Reduction Mediated by Benzo[a]pyrene in Primary Human Colonic Epithelial Cells

NRF2 in Cancer: Cross-Talk with Oncogenic Pathways and Involvement in Gammaherpesvirus-Driven Carcinogenesis

The complex network of mTOR signalling in the heart

Treatment with the bacterial toxin CNF1 selectively rescues cognitive and brain mitochondrial deficits in a female mouse model of Rett syndrome carrying a MeCP2-null mutation

Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles

Autophagy and the lysosomal system in cancer

mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder

Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties

Oxidative stress and mTOR in Down syndrome brain: Link to Alzheimerâs dysmetabolism, neuropathology, and possible therapies

Upfront treatment with mTOR inhibitor everolimus in pediatric low-grade gliomas: A single-center experience

BVR-A deficiency leads to autophagy impairment through the dysregulation of AMPK/mTOR axis in the brainâImplications for neurodegeneration

mTOR regulation of metabolism in hematologic malignancies

Inhibition of phosphoinositide 3-kinase/protein kinase B signaling hampers the vasopressin-dependent stimulation of myogenic differentiation

Comparison of the effects of synthetic and plant-derived mTOR regulators on healthy human ovarian cells

The autophagy status of cancer stem cells in gliobastoma multiforme: from cancer promotion to therapeutic strategies

Targeting mTOR with MLN0128 Overcomes Rapamycin and Chemoresistant Primary Effusion Lymphoma

Role of mTOR signaling in tumor microenvironment. An overview

Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome

Oleuropein induces AMPK-dependent autophagy in NAFLD mice, regardless of the gender

mTOR in Down syndrome: Role in AÃ and tau neuropathology and transition to Alzheimer disease-like dementia

Targeting mTOR to reduce Alzheimer-related cognitive decline: from current hits to future therapies