Pubblicazioni

Human estrogen receptor α antagonists, part 2: Synthesis driven by rational design, in vitro antiproliferative, and in vivo anticancer evaluation of innovative coumarin-related antiestrogens as breast cancer suppressants

2022 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Kurtanovic, N.; Tomasevic, N.; Matic, S.; Mitrovic, M. M.; Kostic, D. A.; Sabatino, M.; Antonini, L.; Ragno, R.; Mladenovic, M.

Novel Insights on Human Carbonic Anhydrase Inhibitors Based on Coumalic Acid: Design, Synthesis, Molecular Modeling Investigation, and Biological Studies

2022 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Pontecorvi, Virginia; Mori, Mattia; Picarazzi, Francesca; Zara, Susi; Carradori, Simone; Cataldi, Amelia; Angeli, Andrea; Berrino, Emanuela; Chimenti, Paola; Ciogli, Alessia; Secci, Daniela; Guglielmi, Paolo; Supuran, Claudiu T.

New 1 H ‐indole‐2,3‐dione 3‐thiosemicarbazones with 3‐sulfamoylphenyl moiety as selective carbonic anhydrase inhibitors

2022 - ARCHIV DER PHARMAZIE
Eraslan‐elma, Pınar; Akdemir, Atilla; Berrino, Emanuela; Bozdağ, Murat; Supuran, Claudiu T.; Karalı, Nilgün

Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5

2022 - JOURNAL OF MEDICINAL CHEMISTRY
Fiorentino, F.; Castiello, C.; Mai, A.; Rotili, D.

An updated patent review on monoamine oxidase (MAO) inhibitors

2022 - EXPERT OPINION ON THERAPEUTIC PATENTS
Guglielmi, Paolo; Carradori, Simone; D'Agostino, Ilaria; Campestre, Cristina; Petzer, Jacobus P

Active components from Cassia abbreviata prevent hiv-1 entry by distinct mechanisms of action

2021 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Zheng, Y.; Yang, X. -W.; Schols, D.; Mori, M.; Botta, B.; Chevigne, A.; Mulinge, M.; Steinmetz, A.; Schmit, J. -C.; Seguin-Devaux, C.

6-Fluorophenylbenzohydrazides inhibit Mycobacterium tuberculosis growth through alteration of tryptophan biosynthesis

2021 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Consalvi, S.; Venditti, G.; Zhu, J.; Boshoff, H. I.; Arora, K.; De Logu, A.; Ioerger, T. R.; Rubin, E. J.; Biava, M.; Poce, G.

New aspects of monoamine oxidase b inhibitors: The key role of halogens to open the golden door

2021 - CURRENT MEDICINAL CHEMISTRY
Mathew, B.; Carradori, S.; Guglielmi, P.; Uddin, M. D.; Kim, H.

Emerging Therapeutic Potential of SIRT6 Modulators

2021 - JOURNAL OF MEDICINAL CHEMISTRY
Fiorentino, F.; Mai, A.; Rotili, D.

In silico and in vitro analysis of major cannabis-derived compounds as fatty acid amide hydrolase inhibitors

2021 - MOLECULES
Criscuolo, E.; De Sciscio, M. L.; Fezza, F.; Maccarrone, M.

Oligosaccharides derived from tramesan. Their structure and activity on mycotoxin inhibition in aspergillus flavus and Aspergillus carbonarius

2021 - BIOMOLECULES
Loncar, J.; Bellich, B.; Parroni, A.; Reverberi, M.; Rizzo, R.; Zjalic, S.; Cescutti, P.

Tetrahydroquinazole-based secondary sulphonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IV, and IX, and computational studies

2021 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Baglini, E; Ravichandran, R; Berrino, E; Salerno, S; Barresi, E; Marini, Am; Viviano, M; Castellano, S; Da Settimo, F; Supuran, Ct; Cosconati, S; Taliani, S.

Catechols: A new class of carbonic anhydrase inhibitors

2020 - CHEMICAL COMMUNICATIONS
D'Ambrosio, K.; Carradori, S.; Cesa, S.; Angeli, A.; Monti, S. M.; Supuran, C. T.; De Simone, G.

Interaction of 2,6,7-Trihydroxy-Xanthene-3-Ones with Iron and Copper, and Biological Effect of the Most Active Derivative on Breast Cancer Cells and Erythrocytes

2020 - APPLIED SCIENCES
(r))emysl Mlad( (e))nka, P(; Karl('(i))( (c))kov('(a)), Jana; Hrub( (s))a, Marcel; Veljovi('(c)), Elma; Muratovi('(c)), Samija; Carazo, Alejandro; Shivling Mali, Akash; ( (S))pirtovi('(c))-Halilovi('(c)), Selma; Saso, Luciano; Pour, Milan; Duri('(c)), Kemal

Naturally-occurring alkaloids of plant origin as potential antimicrobials against antibiotic-resistant infections

2020 - MOLECULES
Casciaro, B.; Mangiardi, L.; Cappiello, F.; Romeo, I.; Loffredo, M. R.; Iazzetti, A.; Calcaterra, A.; Goggiamani, A.; Ghirga, F.; Mangoni, M. L.; Botta, B.; Quaglio, D.

Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 integrase and reverse transcriptase associated ribonuclease H inhibitors

2020 - ANTIVIRAL RESEARCH
Esposito, F.; Sechi, M.; Pala, N.; Sanna, A.; Koneru, P. C.; Kvaratskhelia, M.; Naesens, L.; Corona, A.; Grandi, N.; di Santo, R.; D'Amore, V. M.; Di Leva, F. S.; Novellino, E.; Cosconati, S.; Tramontano, E.

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-7

2020 - MOLECULES
Gutschow, M.; Eynde, J. J. V.; Jampilek, J.; Kang, C.; Mangoni, A. A.; Fossa, P.; Karaman, R.; Trabocchi, A.; Scott, P. J. H.; Reynisson, J.; Rapposelli, S.; Galdier, S.; Winum, J. -Y.; Brullo, C.; Prokai-Tatrai, K.; Sharma, A. K.; Schapira, M.; Azuma, Y. -T.; Cerchia, L.; Spete, M.; Torri, G.; Collina, S.; Geronikaki, A.; Garcia-Sosa, A. T.; Helena Vasconcelos, M.; Sousa, M. E.; Kosalec, I.; Tuccinardi, T.; Duarte, I. F.; Salvador, J. A. R.; Bertinaria, M.; Pellecchia, M.; Amato, J.; Rastelli, G.; Gomes, P. A. C.; Guedes, R. C.; Sabatier, J. -M.; Estevez-Braun, A.; Pagano, B.; Mangani, S.; Ragno, R.; Kokotos, G.; Brindisi, M.; Gonzalez, F. V.; Borges, F.; Miloso, M.; Rautio, J.; Munoz-Torrero, D.

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold

2019 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Rotondi, G.; Guglielmi, P.; Carradori, S.; Secci, D.; De Monte, C.; De Filippis, B.; Maccallini, C.; Amoroso, R.; Cirilli, R.; Akdemir, A.; Angeli, A.; Supuran, C. T.

Small molecules with anti prion activity

2019 - CURRENT MEDICINAL CHEMISTRY
Mustazza, C; Sbriccoli, M; Minosi, P; Raggia, C.

Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis

2019 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Di Paolo, V.; Fulci, C.; Rotili, D.; Sciarretta, F.; Lucidi, A.; Morozzo della Rocca, B.; De Luca, A.; Rosato, A.; Quintieri, L.; Caccuri, A. M.

Synthesis and structure-activity relationship of nitrile-based cruzain inhibitors incorporating a trifluoroethylamine-based P2 amide replacement

2019 - BIOORGANIC & MEDICINAL CHEMISTRY
Gomes, Juliana C; Cianni, Lorenzo; Ribeiro, Jean; Dos Reis Rocho, Fernanda; da Costa Martins Silva, Samelyn; Batista, Pedro Henrique Jatai; Moraes, Carolina Borsoi; Franco, Caio Haddad; Freitas-Junior, Lucio H G; Kenny, Peter W; Leitão, Andrei; Burtoloso, Antonio C B; de Vita, Daniela; Montanari, Carlos A

Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes

2018 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Bua, Silvia; Berrino, Emanuela; Del Prete, Sonia; Murthy, Vallabhaneni S; Vijayakumar, Vijayaparthasarathi; Tamboli, Yasinalli; Capasso, Clemente; Cerbai, Elisabetta; Mugelli, Alessandro; Carta, Fabrizio; Supuran, Claudiu T

MAO inhibitors and their wider applications: a patent review

2018 - EXPERT OPINION ON THERAPEUTIC PATENTS
Carradori, Simone; Secci, Daniela; Petzer, Jacques P.

Efficient synthesis and first regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold and their evaluation in H2O2-induced oxidative stress

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Loubidi, Mohammed; Jouha, Jabrane; Tber, Zahira; Khouili, Mostafa; Suzenet, Franck; Akssira, Mohamed; Erdogan, Mümin Alper; Köse, Fadime Aydın; Dagcı, Taner; Armagan, Güliz; Saso, Luciano; Guillaumet, Gérald

9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-xanthene-3-one is a potentially novel antiplatelet drug which antagonizes the effect of thromboxane A2

2018 - MEDICINAL CHEMISTRY
Applová, Lenka; Veljović, Elma; Muratović, Samija; Karlíčková, Jana; Macáková, Kateřina; Završnik, Davorka; Saso, Luciano; Durić, Kemal; Mladĕnka, Přemysl

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