Pubblicazioni

Belimumab decreases autophagy and citrullination in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

2022 - CELLS

Colasanti, T.; Spinelli, F. R.; Barbati, C.; Ceccarelli, F.; Scarpa, S.; Vomero, M.; Alessandri, C.; Valesini, G.; Conti, F.

The impact of autophagy modulation on phenotype and survival of cardiac stromal cells under metabolic stress

2022 - CELL DEATH DISCOVERY

Chimenti, Isotta; Picchio, Vittorio; Pagano, Francesca; Schirone, Leonardo; Schiavon, Sonia; D'Ambrosio, Luca; Valenti, Valentina; Forte, Maurizio; di Nonno, Flavio; Rubattu, Speranza Donatella; Peruzzi, Mariangela; Versaci, Francesco; Greco, Ernesto; Calogero, Antonella; De Falco, Elena; Frati, Giacomo; Sciarretta, Sebastiano

Targeting the anti-apoptotic Bcl-2 family proteins: Machine learning virtual screening and biological evaluation of new small molecules

2022 - THERANOSTICS

Valentini, E.; D'Aguanno, S.; Di Martile, M.; Montesano, C.; Ferraresi, V.; Patsilinakos, A.; Sabatino, M.; Antonini, L.; Chiacchiarini, M.; Valente, S.; Mai, A.; Colotti, G.; Ragno, R.; Trisciuoglio, D.; Del Bufalo, D.

The dysregulation of autophagy and ER stress induced by HHV-6A infection activates pro-inflammatory pathways and promotes the release of inflammatory cytokines and cathepsin S by CNS cells

2022 - VIRUS RESEARCH

Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Arena, A.; Gaeta, A.; Cirone, M.

Aging-Related Decline of Autophagy in Patients with Atrial FibrillationâA Post Hoc Analysis of the ATHERO-AF Study

2022 - ANTIOXIDANTS

Versaci, F.; Valenti, V.; Forte, M.; Cammisotto, V.; Nocella, C.; Bartimoccia, S.; Schirone, L.; Schiavon, S.; Vecchio, D.; D'ambrosio, L.; Spinosa, G.; D'amico, A.; Chimenti, I.; Violi, F.; Frati, G.; Pignatelli, P.; Sciarretta, S.; Pastori, D.; Carnevale, R.

3,4-Dihydroxyphenylethanol (DPE or Hydroxytyrosol) Counteracts ERK1/2 and mTOR Activation, Pro-Inflammatory Cytokine Release, Autophagy and Mitophagy Reduction Mediated by Benzo[a]pyrene in Primary Human Colonic Epithelial Cells

2022 - PHARMACEUTICS

Santarelli, R.; Pompili, C.; Gilardini Montani, M. S.; Evangelista, L.; Gonnella, R.; Cirone, M.

The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells

2022 - BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Arena, A.; Romeo, M. A.; Benedetti, R.; Gilardini Montani, M. S.; Cirone, M.

Restoration of ER proteostasis attenuates remote apoptotic cell death after spinal cord injury by reducing autophagosome overload

2022 - CELL DEATH & DISEASE

Bisicchia, E.; Mastrantonio, R.; Nobili, A.; Palazzo, C.; La Barbera, L.; Latini, L.; Millozzi, F.; Sasso, V.; Palacios, D.; D'Amelio, M.; Viscomi, M. T.

Tofacitinib Decreases Autophagy of Fibroblast-Like Synoviocytes From Rheumatoid Arthritis Patients

2022 - FRONTIERS IN PHARMACOLOGY

Progressive stages of dysmetabolism are associated with impaired biological features of human cardiac stromal cells mediated by the oxidative state and autophagy

2022 - JOURNAL OF PATHOLOGY

Pagano, Francesca; Picchio, Vittorio; Bordin, Antonella; Cavarretta, Elena; Nocella, Cristina; Cozzolino, Claudia; Floris, Erica; Angelini, Francesco; Sordano, Alessia; Peruzzi, Mariangela; Miraldi, Fabio; Biondi-Zoccai, Giuseppe; De Falco, Elena; Carnevale, Roberto; Sciarretta, Sebastiano; Frati, Giacomo; Chimenti, Isotta

Autophagy Hijacking in PBMC From COVID-19 Patients Results in Lymphopenia

2022 - FRONTIERS IN IMMUNOLOGY

Barbati, Cristiana; Celia, Alessandra Ida; Colasanti, Tania; Vomero, Marta; Speziali, Mariangela; Putro, Erisa; Buoncuore, Giorgia; Savino, Flavia; Colafrancesco, Serena; Ucci, Federica Maria; Ciancarella, Claudia; Balbinot, Eugenia; Scarpa, Susanna; Natalucci, Francesco; Pellegrino, Greta; Ceccarelli, Fulvia; Spinelli, Francesca Romana; Mastroianni, Claudio Maria; Conti, Fabrizio; Alessandri, Cristiano

Î²-Caryophyllene Counteracts Chemoresistance Induced by Cigarette Smoke in Triple-Negative Breast Cancer MDA-MB-468 Cells

2022 - BIOMEDICINES

Di Sotto, Antonella; Gulli, Marco; Minacori, Marco; Mancinelli, Romina; Garzoli, Stefania; Percaccio, Ester; Incocciati, Alessio; Romaniello, Donatella; Mazzanti, Gabriela; Eufemi, Margherita; Di Giacomo, Silvia

The TLR4/NFÎºB-Dependent Inflammatory Response Activated by LPS Is Inhibited in Human Macrophages Pre-Exposed to Amorphous Silica Nanoparticles

2022 - NANOMATERIALS

Bianchi, M. G.; Chiu, M.; Taurino, G.; Bergamaschi, E.; Cubadda, F.; Macaluso, G. M.; Bussolati, O.

Cross-talk between autophagy and apoptosis in an experimental in vitro model of cholangiocarcinoma

2022 - ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGYItalian Journal of Anatomy and Embryology

Giampietri, Claudia; Petrungaro, Simonetta; DE FRANCHIS, Valerio; Filippini, Antonio; Gaudio, Eugenio

Natural Activators of Autophagy Increase Maximal Walking Distance and Reduce Oxidative Stress in Patients with Peripheral Artery Disease: A Pilot Study

2022 - ANTIOXIDANTS

Martinelli, Ombretta; Peruzzi, Mariangela; Bartimoccia, Simona; D'Amico, Alessandra; Marchitti, Simona; Rubattu, Speranza; Chiariello, Giovanni Alfonso; D'Ambrosio, Luca; Schiavon, Sonia; Miraldi, Fabio; Saade, Wael; D'Abramo, Mizar; Pingitore, Annachiara; Loffredo, Lorenzo; Nocella, Cristina; Forte, Maurizio; Pignatelli, Pasquale

Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells

2022 - CANCER GENE THERAPY

Ansari, Mohammad Salik Zeya; Stagni, Venturina; Iuzzolino, Angela; Rotili, Dante; Mai, Antonello; Del Bufalo, Donatella; Lavia, Patrizia; Degrassi, Francesca; Trisciuoglio, Daniela

Neuropeptide Y promotes human M2 macrophage polarization and enhances p62/SQSTM1-dependent autophagy and NRF2 activation

2022 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Profumo, Elisabetta; Maggi, Elisa; Arese, Marzia; Di Cristofano, Claudio; Salvati, Bruno; Saso, Luciano; Businaro, Rita; Buttari, Brigitta

Interconnected Adaptive Responses: A Way Out for Cancer Cells to Avoid Cellular Demise

2022 - CANCERS

D'Orazi, Gabriella; Cirone, Mara

Mechanisms of Sensitivity and Resistance of Primary Effusion Lymphoma to Dimethyl Fumarate (DMF)

2022 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gonnella, Roberta; Zarrella, Roberta; Santarelli, Roberta; Germano, Concetta Anna; Gilardini Montani, Maria Saveria; Cirone, Mara

NRF2 in Cancer: Cross-Talk with Oncogenic Pathways and Involvement in Gammaherpesvirus-Driven Carcinogenesis

2022 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cirone, Mara; D'Orazi, Gabriella

Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy

2022 - SCIENCE ADVANCES

Di Lorenzo, G.; Iavarone, F.; Maddaluno, M.; Plata-Gomez, A. B.; Aureli, S.; Meza, C. P. Q.; Cinque, L.; Palma, A.; Reggio, A.; Cirillo, C.; Sacco, F.; Stolz, A.; Napolitano, G.; Marin, O.; Pinna, L. A.; Ruzzene, M.; Limongelli, V.; Efeyan, A.; Grumati, P.; Settembre, C.

Autophagy in Rheumatic Diseases: Role in the Pathogenesis and Therapeutic Approaches

2022 - CELLS

Celia, A. I.; Colafrancesco, S.; Barbati, C.; Alessandri, C.; Conti, F.

Allethrin Promotes Apoptosis and Autophagy Associated with the Oxidative Stress-Related PI3K/AKT/mTOR Signaling Pathway in Developing Rat Ovaries

2022 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Jalouli, Maroua; Mofti, Afoua; Elnakady, Yasser A; Nahdi, Saber; Feriani, Anouar; Alrezaki, Abdelkarem; Sebei, Khaled; Bizzarri, Mariano; Alwasel, Saleh; Harrath, Abdel Halim

Regulation of calcium handling by autophagy: a novel mechanism limiting cardiac hypertrophy and dysfunction?

2022 - CARDIOVASCULAR RESEARCH

Forte, M.; Frati, G.; Sciarretta, S.

Tofacitinib decreases autophagy of fibroblast-like synoviocytes from rheumatoid arthritis patients

2022 - FRONTIERS IN PHARMACOLOGY

Vomero, M.; Caliste, M.; Barbati, C.; Speziali, M.; Celia, A. I.; Ucci, F.; Ciancarella, C.; Putro, E.; Colasanti, T.; Buoncuore, G.; Corsiero, E.; Bombardieri, M.; Spinelli, F. R.; Ceccarelli, F.; Conti, F.; Alessandri, C.