Pubblicazioni

Synthesis and carbonic anhydrase inhibitory properties of novel 4-(2-aminoethyl)benzenesulfonamide-dipeptide conjugates

2019 - BIOORGANIC CHEMISTRY

KÃ¼Ã§Ã¼kbay, Hasan; BuÄday, Nesrin; KÃ¼Ã§Ã¼kbay, F. Zehra; Berrino, Emanuela; Bartolucci, Gian Luca; Del Prete, Sonia; Capasso, Clemente; Supuran, Claudiu T.

Targeting metabotropic glutamate receptors in the treatment of primary brain tumors

2018 - CURRENT OPINION IN PHARMACOLOGY

Iacovelli, Luisa; Orlando, Rosamaria; Rossi, Alessandro; Spinsanti, Paola; Melchiorri, Daniela; Nicoletti, Ferdinando

Metabotropic glutamate receptors: the potential for therapeutic applications in Alzheimer's disease

2018 - CURRENT OPINION IN PHARMACOLOGY

Caraci, Filippo; Nicoletti, Ferdinando; Copani, Agata

Fluorometric detection of protein-ligand engagement: The case of phosphodiesterase5

2018 - JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Di Rocco, Giulia; Martinelli, Ilaria; Pacifico, Salvatore; Guerrini, Remo; Cichero, Elena; Fossa, Paola; Franchini, Silvia; Cardarelli, Silvia; Giorgi, Mauro; Sola, Marco; Ponterini, Glauco

Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Berardozzi, Simone; Bernardi, Flavia; Infante, Paola; Ingallina, Cinzia; Toscano, Sara; De Paolis, Elisa; Alfonsi, Romina; Caimano, Miriam; Botta, Bruno; Mori, Mattia; Di Marcotullio, Lucia; Ghirga, Francesca

Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors

2018 - MOLECULAR PHARMACEUTICS

Ilari, Andrea; Genovese, Ilaria; Fabiana, Fiorillo; Battista, Theo; Ilenia De Ionna, ; Fiorillo, Annarita; Colotti, Gianni

Identification of chalcone-based antileishmanial agents targeting trypanothione reductase

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Ortalli, M; Ilari, Andrea; Colotti, G; De Ionna, I; Battista, Theo; Bisi, A; Gobbi, S; Rampa, A; Di Martino RMC, ; Gentilomi, Ga; Varani, S; Belluti, F.

Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents

2018 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Saccoliti, Francesco; Madia, VALENTINA NOEMI; Tudino, Valeria; DE LEO, Alessandro; Pescatori, Luca; Messore, Antonella; DE VITA, Daniela; Scipione, Luigi; Brun, Reto; Kaiser, Marcel; MÃ¤ser, Pascal; Magalhaes Calvet, Claudia; K Jennings, Gareth; M Podust, Larissa; Costi, Roberta; DI SANTO, Roberto

Kinetics of lycopene degradation in sunflower and grape seed oils

2018 - ORIENTAL JOURNAL OF CHEMISTRY

Zuorro, Antonio; Lavecchia, Roberto; GonzÃ¡lez, Erenio; Kafarov, Viatcheslav

From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at Î±4Î²2 nicotinic acetylcholine receptor

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Bolchi, Cristiano; Bavo, Francesco; Gotti, Cecilia; Fumagalli, Laura; Fasoli, Francesca; Binda, Matteo; Mucchietto, Vanessa; Sciaccaluga, Miriam; Plutino, Simona; Fucile, Sergio; Pallavicini, Marco

3-Phenylalkyl-2H-chromenes and -chromans as novel rhinovirus infection inhibitors

2017 - BIOORGANIC & MEDICINAL CHEMISTRY

Conti, Cinzia; PROIETTI MONACO, Luca; Desideri, Nicoletta

Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal grafting

2017 - DRUG DESIGN, DEVELOPMENT AND THERAPY

Marianecci, Carlotta; Rinaldi, Federica; Hanieh, PATRIZIA NADIA; Di Marzio, Luisa; Paolino, Donatella; Carafa, Maria

pH-sensitive niosomes: effects on cytotoxicity and on inflammation and pain in murine models

2017 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Rinaldi, Federica; Del Favero, Elena; Rondelli, Valeria; Pieretti, Stefano; Bogni, Alessia; Ponti, Jessica; Rossi, FranÃ§ois; Di Marzio, Luisa; Paolino, Donatella; Marianecci, Carlotta; Carafa, Maria

Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Zwergel, Clemens; Czepukojc, Brigitte; Evain Bana, Emilie; Xu, Zhanjie; Stazi, Giulia; Mori, Mattia; Patsilinakos, Alexandros; Mai, Antonello; Botta, Bruno; Ragno, Rino; Bagrel, Denise; Kirsch, Gilbert; Meiser, Peter; Jacob, Claus; Montenarh, Mathias; Valente, Sergio

Enhancing activity and selectivity in a series of pyrrol-1-yl-1-hydroxypyrazole-based aldose reductase inhibitors: the case of trifluoroacetylation

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Papastavrou, Nikolaos; Chatzopoulou, Maria; Ballekova, Jana; Cappiello, Mario; Moschini, Roberta; Balestri, Francesco; Patsilinakos, Alexandros; Ragno, Rino; Stefek, Milan; Nicolaou, Ioannis

Enantiomers of triclabendazole sulfoxide: analytical and semipreparative HPLC separation, absolute configuration assignment, and transformation into sodium salt

2017 - JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Ferretti, Rosella; Carradori, Simone; Guglielmi, Paolo; Pierini, Marco; Casulli, Adriano; Cirilli, Roberto

Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases

2017 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Evain Bana, Emilie; Schiavo, Lucie; Bour, Christophe; Lanfranchi, Don Antoine; Berardozzi, Simone; Ghirga, Francesca; Bagrel, Denyse; Botta, Bruno; Hanquet, Gilles; Mori, Mattia

SOS response in bacteria. Inhibitory activity of lichen secondary metabolites against Escherichia coli RecA protein

2017 - PHYTOMEDICINE

Bellio, Pierangelo; DI PIETRO, Letizia; Mancini, Alisia; Piovano, Marisa; Nicoletti, Marcello; Brisdelli, Fabrizia; Tondi, Donatella; Cendron, Laura; Franceschini, Nicola; Amicosante, Gianfranco; Perilli, Mariagrazia; Celenza, Giuseppe

Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: evaluation of antimicrobial, cytotoxic and hemolytic activities

2017 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Merlino, Francesco; Carotenuto, Alfonso; Casciaro, Bruno; Martora, Francesca; Loffredo, MARIA ROSA; DI GRAZIA, Antonio; Yousif, Ali M.; Brancaccio, Diego; Palomba, Luciana; Novellino, Ettore; Galdiero, Massimiliano; Iovene, Maria Rosaria; Mangoni, Maria Luisa; Grieco, Paolo

Effects of curcumin and curcumin analogues on TRP channels

2017 - FITOTERAPIA

Nalli, Marianna; Ortar, Giorgio; Schiano Moriello, Aniello; Di Marzo, Vincenzo; De Petrocellis, Luciano

The sodium salt of the enantiomers of ricobendazole: preparation, solubility and chiroptical properties

2017 - JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Cirilli, Roberto; Guglielmi, Paolo; Formica, Francesca Romana; Casulli, Adriano; Carradori, Simone

Analysis of imidazoles and triazoles in biological samples after MicroExtraction by packed sorbent

2017 - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Campestre, Cristina; Locatelli, Marcello; Guglielmi, Paolo; De Luca, Elisa; Bellagamba, Giuseppe; Menta, Sergio; Zengin, Gokhan; Celia, Christian; Di Marzio, Luisa; Carradori, Simone

New perspectives in glioblastoma: Nanoparticles-based approaches

2017 - CURRENT CANCER DRUG TARGETS

Luciano, Rosa; Battafarano, Giulia; Saracino, Rossana; Rossi, Michela; Perrotta, Antonio; Manco, Melania; Muraca, Maurizio; Del Fattore, Andrea

Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group

2017 - ACS MEDICINAL CHEMISTRY LETTERS

Lassalas, Pierrik; Oukoloff, Killian; Makani, Vishruti; James, Michael; Tran, Van; Yao, Yuemang; Huang, Longchuan; Vijayendran, Krishna; Monti, Ludovica; Trojanowski, John Q.; Lee, Virginia M. -. Y.; Kozlowski, Marisa C.; Smith, Amos B.; Brunden, Kurt R.; Ballatore, Carlo

Anti-catabolic neurohormonal blockade to improve skeletal muscle during disease

2017 - EXPERT OPINION ON BIOLOGICAL THERAPY

Molfino, Alessio; Amabile, Maria Ida; Muscaritoli, Maurizio