Pubblicazioni

Addition to “The death of the strategy of classical chiral switches Is an exaggeration”

2025 - ACS MEDICINAL CHEMISTRY LETTERS
Agranat, Israel; D'Acquarica, Ilaria

Chiral Switches of Tramadol Hydrochloride, a Potential Psychedelic Drug─Past and Future

2024 - ACS MEDICINAL CHEMISTRY LETTERS
Agranat, Israel; D'Acquarica, Ilaria

Quinolinonyl Derivatives as Dual Inhibitors of the HIV-1 Integrase Catalytic Site and Integrase-RNA interactions

2024 - ACS MEDICINAL CHEMISTRY LETTERS
Patacchini, E.; Madia, V. N.; Albano, A.; Ruggieri, G.; Messore, A.; Ialongo, D.; Saccoliti, F.; Scipione, L.; Cosconati, S.; Koneru, P. C.; Haney, R.; Kvaratskhelia, M.; Di Santo, R.; Costi, R.

The Death of the Strategy of Classical Chiral Switches Is an Exaggeration

2024 - ACS MEDICINAL CHEMISTRY LETTERS
Agranat, Israel; D'Acquarica, Ilaria

Rimonabant-Based Compounds Bearing Hydrophobic Amino Acid Derivatives as Cannabinoid Receptor Subtype 1 Ligands

2023 - ACS MEDICINAL CHEMISTRY LETTERS
Dvorácskó, Szabolcs; Dimmito, Marilisa Pia; Sebastiani, Jessica; La Regina, Giuseppe; Silvestri, Romano; Pieretti, Stefano; Stefanucci, Azzurra; Tömböly, Csaba; Mollica, Adriano

An innovation 10 years in the making: the stories in the pages of ACS Medicinal Chemistry Letters

2022 - ACS MEDICINAL CHEMISTRY LETTERS
Altman, R. A.; Brai, A.; Golden, J.; La Regina, G.; Li, Z.; Moore, T. W.; Pomerantz, W. C. K.; Rajapaksa, N. S.; Adams, A. M.

Structural Rigidification of N-Aryl-pyrroles into Indoles Active against Intracellular and Drug-Resistant Mycobacteria

2021 - ACS MEDICINAL CHEMISTRY LETTERS
Semenya, Dorothy; Touitou, Meir; Ribeiro, Camila Maringolo; Pavan, Fernando Rogerio; Pisano, Luca; Singh, Vinayak; Chibale, Kelly; Bano, Georg; Toscani, Anita; Manetti, Fabrizio; Gianibbi, Beatrice; Castagnolo, Daniele

Discovery of new 1,1'-biphenyl-4-sulfonamides as selective subnanomolar human carbonic anhydrase II inhibitors

2020 - ACS MEDICINAL CHEMISTRY LETTERS
La Regina, G.; Puxeddu, M.; Nalli, M.; Vullo, D.; Gratteri, P.; Supuran, C. T.; Nocentini, A.; Silvestri, R.

From parp1 to tnks2 Inhibition: a structure-based approach

2020 - ACS MEDICINAL CHEMISTRY LETTERS
Tomassi, Stefano; Pfahler, Julian; Mautone, Nicola; Rovere, Annarita; Esposito, Chiara; Passeri, Daniela; Pellicciari, Roberto; Novellino, Ettore; Pannek, Martin; Steegborn, Clemens; Paiardini, Alessandro; Mai, Antonello; Rotili, Dante

Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells

2020 - ACS MEDICINAL CHEMISTRY LETTERS
Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio

Artemisinin derivatives with antimelanoma activity show inhibitory effect against human dna topoisomerase 1

2020 - ACS MEDICINAL CHEMISTRY LETTERS
Botta, Lorenzo; Filippi, Silvia; Zippilli, Claudio; Cesarini, Silvia; Bizzarri, Bruno Mattia; Cirigliano, Angela; Rinaldi, Teresa; Paiardini, Alessandro; Fiorucci, Diego; Saladino, Raffaele; Negri, Rodolfo; Benedetti, Pietro

Structural elucidation and antimicrobial characterization of novel diterpenoids from fabiana densa var. ramulosa

2020 - ACS MEDICINAL CHEMISTRY LETTERS
Quaglio, Deborah; Corradi, Silvia; Erazo, Silvia; Vergine, Valeria; Berardozzi, Simone; Sciubba, Fabio; Cappiello, Floriana; Crestoni, Maria Elisa; Ascenzioni, Fiorentina; Imperi, Francesco; Delle Monache, Franco; Mori, Mattia; Loffredo, Maria Rosa; Ghirga, Francesca; Casciaro, Bruno; Botta, Bruno; Mangoni, Maria Luisa

Pyrrolyl pyrazoles as non-diketo acid inhibitors of the HIV-1 ribonuclease H function of reverse transcriptase

2020 - ACS MEDICINAL CHEMISTRY LETTERS
Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Di Maro, Salvatore; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Valenti, Piera; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto

Discovery of Zika virus NS2B/NS3 inhibitors that prevent mice from fife-threatening infection and brain damage

2020 - ACS MEDICINAL CHEMISTRY LETTERS
Coluccia, A.; Puxeddu, M.; Nalli, M.; Wei, C. K.; Wu, Y. H.; Mastrangelo, E.; Elamin, T.; Tarantino, D.; Bugert, J. J.; Schreiner, B.; Nolte, J.; Schwarze, F.; La Regina, G.; Lee, J. C.; Silvestri, R.

In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae.

2020 - ACS MEDICINAL CHEMISTRY LETTERS
Mancuso, F; De Luca, L; Angeli, A; Berrino, E; Del Prete, S; Capasso, C; Supuran, Ct; Gitto, R.

Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction

2020 - ACS MEDICINAL CHEMISTRY LETTERS
Ontoria, Jesus M; Biancofiore, Ilaria; Fezzardi, Paola; Ferrigno, Federica; Torrente, Esther; Colarusso, Stefania; Bianchi, Elisabetta; Andreini, Matteo; Patsilinakos, Alexandros; Kempf, Georg; Augustin, Martin; Steinbacher, Stefan; Summa, Vincenzo; Pacifici, Robert; Muñoz-Sanjuan, Ignacio; Park, Larry; Bresciani, Alberto; Dominguez, Celia; Sherman, Leticia Toledo; Harper, Steven

Drug design and synthesis of first in class PDZ1 targeting NHERF1 inhibitors as anticancer agents

2019 - ACS MEDICINAL CHEMISTRY LETTERS
Coluccia, A.; La Regina, G.; Naccarato, V.; Nalli, M.; Orlando, V.; Biagioni, S.; De Angelis, M. L.; Baiocchi, M.; Gautier, C.; Gianni, S.; Di Pastena, F.; Di Magno, L.; Canettieri, G.; Coluccia, A. M. L.; Silvestri, R.

Chalcones and chalcone-mimetic derivatives as Notch inhibitors in a model of T-cell Acute Lymphoblastic Leukemia

2019 - ACS MEDICINAL CHEMISTRY LETTERS
Quaglio, Deborah; Zhdanovskaya, Nadezda; Tobajas, Gloria; Cuartas, Viviana; Balducci, Silvia; Christodoulou, Michael S.; Fabrizi, Giancarlo; Gargantilla, Marta; Priego, Eva-María; CARMONA PESTAñA, Alvaro; Passarella, Daniele; Screpanti, Isabella; Botta, Bruno; Palermo, Rocco; Mori, Mattia; Ghirga, Francesca; Pérez-Pérez, María-Jesús

Novel pyrazole-containing compounds active against mycobacterium tuberculosis

2019 - ACS MEDICINAL CHEMISTRY LETTERS
Poce, Giovanna; Consalvi, Sara; Venditti, Giulia; Alfonso, Salvatore; Desideri, Nicoletta; Fernandez-Menendez, Raquel; Bates, Robert H.; Ballell, Lluis; Barros Aguirre, David; Rullas, Joaquin; De Logu, Alessandro; Gardner, Michelle; Ioerger, Thomas R.; Rubin, Eric J.; Biava, Mariangela

α,γ-Diketocarboxylic acids and their esters act as carbonic anhydrase IX and XII selective inhibitors

2019 - ACS MEDICINAL CHEMISTRY LETTERS
Nocentini, Alessio; Lucidi, Alessia; Perut, Francesca; Massa, Annamaria; TOMASELLI, DANIELA; Gratteri, Paola; Baldini, Nicola; ROTILI, Dante; MAI, Antonello; Supuran, Claudiu T.

3-Aroyl-1,4-diarylpyrroles inhibit chronic myeloid leukemia cell growth through an interaction with tubulin

2017 - ACS MEDICINAL CHEMISTRY LETTERS
LA REGINA, Giuseppe; Bai, R.; Coluccia, Antonio; Famiglini, Valeria; Passacantilli, Sara; Naccarato, Valentina; Ortar, Giorgio; Mazzoccoli, Carmela; Ruggieri, V.; Agriesti, F.; Piccoli, C.; Tataranni, T.; Nalli, Marianna; Brancale, A.; Vultaggio, S.; Mercurio, C.; Varasi, M.; Saponaro, C.; Sergio, S.; Maffia, M.; Coluccia, A. M. L.; Hamel, E.; Silvestri, Romano

Opioid receptor activity and analgesic potency of DPDPE peptide analogues containing a xylene bridge.

2017 - ACS MEDICINAL CHEMISTRY LETTERS
Stefanucci, A; Novellino, E; Mirzaie, S; Macedonio, G; Pieretti, S; Minosi, P; Szűcs, E; Erdei, Ai; Zádor, F; Benyhe, S; Mollica, A.

Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group

2017 - ACS MEDICINAL CHEMISTRY LETTERS
Lassalas, Pierrik; Oukoloff, Killian; Makani, Vishruti; James, Michael; Tran, Van; Yao, Yuemang; Huang, Longchuan; Vijayendran, Krishna; Monti, Ludovica; Trojanowski, John Q.; Lee, Virginia M. -. Y.; Kozlowski, Marisa C.; Smith, Amos B.; Brunden, Kurt R.; Ballatore, Carlo

Pure diastereomers of a tranylcypromine-based LSD1 inhibitor: enzyme selectivity and in-cell studies

2015 - ACS MEDICINAL CHEMISTRY LETTERS
VALENTE, Sergio; Veronica, Rodriguez; Ciro, Mercurio; Paola, Vianello; Bruna, Saponara; Roberto, Cirilli; Giuseppe, Ciossani; LABELLA, DONATELLA; MARROCCO, BIAGINA; RUOPPOLO, Giovanni; Oronza A., Botrugno; Paola, Dessanti; Saverio, Minucci; Andrea, Mattevi; Mario, Varasi; MAI, Antonello

Exploring oxidovanadium(IV) complexes as YopH inhibitors: mechanism of action and modeling studies

2015 - ACS MEDICINAL CHEMISTRY LETTERS
Martins, Priscila G. A; Mori, Mattia; Chiaradia Delatorre, Louise D; Menegatti, Angela C. O; Mascarello, Alessandra; Botta, Bruno; Benítez, Julio; Gambino, Dinorah; Terenzi, Hernán

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