Pubblicazioni

Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgenindependent prostate cancer cells to DNA damage

2016 - ONCOTARGET

F. Marampon1, 2; Gravina, G. L.; Ju, X.; Vetuschi, A.; Sferra, R.; Casimiro, M. C.; Pompili, S.; Festuccia, C.; Colapietro, A.; Gaudio, Eugenio; Di Cesare, E.; Tombolini, Vincenzo

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic hydroxymethyltransferase and induces cell death in lung cancer cells

2016 - ONCOTARGET

Marani, Marina; Paone, Alessio; Fiascarelli, Alessio; Macone, Alberto; Gargano, Maurizio; Rinaldo, Serena; Giardina, Giorgio; Pontecorvi, Valentino; Koes, David; Mcdermott, Lee; Yang, Tianyi; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola', Francesca

In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.

2016 - ONCOTARGET

Benvenuto, M; Masuelli, Laura; DE SMAELE, Enrico; Fantini, M; Mattera, Rosanna; Cucchi, Danilo; Bonanno, E; DI STEFANO, Enrica; Frajese, Gv; Orlandi, A; Screpanti, Isabella; Gulino, Alberto; Modesti, A; Bei, R.

Expression of the FGFR2 mesenchymal splicing variant in epithelial cells drives epithelial-mesenchymal transition

2016 - ONCOTARGET

Ranieri, Danilo; Rosato, Benedetta; Nanni, Monica; Magenta, Alessandra; Belleudi, Francesca; Torrisi, Maria Rosaria

In normal aging ventricular system never attains pathological values of Evans' index

2016 - ONCOTARGET

Missori, Paolo; Rughetti, Aurelia; Peschillo, Simone; Gualdi, Gianfranco; Biasi, Claudio Di; Nofroni, Italo; Marinelli, Lucio; Fattapposta, Francesco; Curra', Antonio

Dynamics of cytotoxic T cell subsets during immunotherapy predicts outcome in acute myeloid leukemia

2016 - ONCOTARGET

Sander, Frida Ewald; RydstrÃ¶m, Anna; Bernson, Elin; Kiffin, Roberta; Riise, Rebecca; Aurelius, Johan; Anderson, Harald; Brune, Mats; Foa, Roberto; Hellstrand, Kristoffer; ThorÃ©n, Fredrik B; Martner, Anna

Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes

2016 - ONCOTARGET

Messina, Monica; Chiaretti, Sabina; Wang, Jiguang; Fedullo, Anna Lucia; Peragine, Nadia; Gianfelici, Valentina; Piciocchi, Alfonso; Brugnoletti, Fulvia; Di Giacomo, Filomena; Pauselli, Simona; Holmes, Antony B; Puzzolo, Maria Cristina; Ceglie, Giulia; Apicella, Valerio; Mancini, Marco; Te Kronnie, Geertruy; Testi, Anna Maria; Vitale, Antonella; Vignetti, Marco; Guarini, Anna; Rabadan, Raul; Foa, Roberto

The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint

2016 - ONCOTARGET

Di Magno, Laura; Basile, Alessio; Coni, Sonia; Manni, Simona; Sdruscia, Giulia; D'Amico, Davide; Antonucci, Laura; Infante, Paola; De Smaele, Enrico; Cucchi, Danilo; Ferretti, Elisabetta; Di Marcotullio, Lucia; Screpanti, Isabella; Canettieri, Gianluca

Extracorporeal Shock Wave Treatment (ESWT) enhances the in vitro-induced differentiation of human tendon-derived stem/progenitor cells (hTSPCs)

2016 - ONCOTARGET

Leone, Laura; Raffa, Salvatore; Vetrano, Mario; Ranieri, Danilo; Malisan, Florence; Scrofani, Cristina; Vulpiani, MARIA CHIARA; Ferretti, Andrea; Torrisi, Maria Rosaria; Visco, Vincenzo

KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment

2016 - ONCOTARGET

D'Alessandro, Giuseppina; Grimaldi, Alfonso; Chece, Giuseppina; Porzia, Alessandra; Esposito, Vincenzo; Santoro, Antonio; Salvati, Maurizio; Mainiero, Fabrizio; Ragozzino, Davide Antonio; DI ANGELANTONIO, Silvia; Wulff, Heike; Catalano, Myriam; Limatola, Cristina

Molecules that target nucleophosmin for cancer treatment: an update

2016 - ONCOTARGET

Di Matteo, Adele; Franceschini, M; Chiarella, Sara; Rocchio, Serena; Travaglini Allocatelli, Carlo; Federici, L.

Concomitant KIT/BRAF and PDGFRA/BRAF mutations are rare events in gastrointestinal stromal tumors

2016 - ONCOTARGET

Rossi, Sabrina; Sbaraglia, Marta; Dell'Orto, Marta Campo; Gasparotto, Daniela; Cacciatore, Matilde; Boscato, Elena; Carraro, Valentina; Toffolatti, Luisa; Gallina, Giovanna; Niero, Monia; Pilozzi, Emanuela; Mandolesi, Alessandra; Sessa, Fausto; Sonzogni, Aurelio; Mancini, Cristina; Mazzoleni, Guido; Romeo, Salvatore; Maestro, Roberta; Dei Tos, Angelo P.

Pre-treatment evaluation of 5-fluorouracil degradation rate. association of poor and ultra-rapid metabolism with severe toxicity in a colorectal cancer patients cohort

2016 - ONCOTARGET

Mazzuca, Federica; Borro, Marina; Botticelli, Andrea; Mazzotti, Eva; Marchetti, Luca; Gentile, Giovanna; La Torre, Marco; Lionetto, Luana; Simmaco, Maurizio; Marchetti, Paolo

Immunoglobulin gene rearrangements in Chinese and Italian patients with chronic lymphocytic leukemia

2016 - ONCOTARGET

Marinelli, Marilisa; Ilari, Caterina; Xia, Yi; Del Giudice, Ilaria; Cafforio, Luciana; Della Starza, Irene; Raponi, Sara; Mariglia, Paola; Bonina, Silvia; Yu, Zhen; Yang, Wenjuan; Qiu, Lugui; Chan, Thomas; Piciocchi, Alfonso; Kwong, Yok Lam; Tse, Eric; Li, Jianyong; Guarini, Anna; Xu, Wei; Foa, Roberto

IDO1 involvement in mTOR pathway: A molecular mechanism of resistance to mTOR targeting in medulloblastoma

2016 - ONCOTARGET

Folgiero, Valentina; Miele, Evelina; Carai, Andrea; Ferretti, Elisabetta; Alfano, Vincenzo; Po, Agnese; Bertaina, Valentina; Goffredo, Bianca Maria; Benedetti, Maria Chiara; Camassei, Francesca Diomedi; Cacchione, Antonella; Locatelli, Franco; Mastronuzzi, Angela

Efficacy and toxicity of bevacizumab in recurrent ovarian disease: an update meta-analysis on phase III trials

2016 - ONCOTARGET

Marchetti, C; De Felice, Francesca; Palaia, Innocenza; Musella, Angela; Di Donato, Violante; Gasparri, Marialuisa; Musio, D; Muzii, Ludovico; Tombolini, Vincenzo; Benedetti Panici, Pierluigi

Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression.

2016 - ONCOTARGET

Morelli, MARIA BEATRICE; Nabissi, M; Amantini, C; Tomassoni, D; Rossi, F; Cardinali, Claudio; Santoni, M; Arcella, Antonietta; Oliva, Ma; Santoni, Angela; Polidori, C; Mariani, Mp; Santoni, G.

UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response

2016 - ONCOTARGET

Signore, Michele; Buccarelli, Mariachiara; Pilozzi, Emanuela; De Luca, Gabriele; Cappellari, Marianna; Fanciulli, Maurizio; Goeman, Frauke; Melucci, Elisa; Biffoni, Mauro; Ricci Vitiani, Lucia

Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner

2016 - ONCOTARGET

Amantini, C; Morelli, MARIA BEATRICE; Nabissi, M; Cardinali, Claudio; Santoni, M; Gismondi, Angela; Santoni, G.

Cell surgery and growth factors in dry age-related macular degeneration: visual prognosis and morphological study

2016 - ONCOTARGET

Limoli, Paolo Giuseppe; Limoli, Celeste; Vingolo, Enzo Maria; Scalinci, Sergio Zaccaria; Nebbioso, Marcella

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells

2016 - ONCOTARGET

DI MARTILE, Marta; Desideri, Marianna; DE LUCA, Teresa; Gabellini, Chiara; Buglioni, Simonetta; Eramo, Adriana; Sette, Giovanni; Milella, MICHELE STANISLAW; Rotili, Dante; Mai, Antonello; Carradori, Simone; Secci, Daniela; De Maria, Ruggero; Del Bufalo, Donatella; Trisciuoglio, Daniela

Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition

2016 - ONCOTARGET

Lobello, N; Biamonte, Federica; Pisanu, Maria Elena; Faniello, Mc; Jakopin, Å½; Chiarella, E; Giovannone, Ed; Mancini, Rita; Ciliberto, G; Cuda, G; Costanzo, F.

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression

2016 - ONCOTARGET

Ciardiello, Chiara; Roca, Maria Serena; Noto, Alessia; Bruzzese, Francesca; Moccia, Tania; Vitagliano, Carlo; Di Gennaro, Elena; Ciliberto, Gennaro; Roscilli, Giuseppe; Aurisicchio, Luigi; Marra, Emaluele; Mancini, Rita; Budillon, Alfredo; Leone, Alessandra

Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease

2016 - ONCOTARGET

Simile, Maria M.; Latte, Gavinella; Demartis, Maria I.; Brozzetti, Stefania; Calvisi, Diego F.; Porcu, Alberto; Feo, Claudio F.; Seddaiu, Maria A.; Daino, Lucia; Berasain, Carmen; Tomasi, Maria L.; Avila, Matias A.; Feo, Francesco; Pascale, Rosa M.

Visceral fat adipocytes from obese and colorectal cancer subjects exhibit distinct secretory and Ï6 polyunsaturated fatty acid profiles and deliver immunosuppressive signals to innate immunity cells

2016 - ONCOTARGET

Del CornÃ², Manuela; D'Archivio, Massimo; Conti, Lucia; Scazzocchio, Beatrice; VarÃ¬, Rosaria; Donninelli, Gloria; Varano, Barbara; Giammarioli, Stefania; DE MEO, Simone; Silecchia, Gianfranco; PennestrÃ¬, Francesco; Persiani, Roberto; Masella, Roberta; Gessani, Sandra